Qianjiang Evening News·Hours News Correspondent Zhu Yaoling Reporter Zhang Bingqing
Will the bones of humans dissolve? A 13-year-old girl actually has osteoporosis ?
Recently, experts from Zhejiang University’s pediatric hospital have encountered very rare cases. A 13-year-old Henan girl Xiuxiu (pseudonym), had multiple fractures on her body and was pushed to the hospital by her mother. After examination, the child found that the osteoporosis was severe. In layman's terms, the bones all over the body began to dissolve, and the cause was finally locked into parathyroid tumor.
"Serious abnormal bone density caused by parathyroid tumors is very rare in clinical practice. After years of experience, I have encountered less than 10 cases." Wang Jinhu, deputy director of pediatric surgery and deputy director of oncology surgery at Zhejiang University Kennel, revealed.
Deputy Director of Orthopedics Chen Wenhao said that fractures, leg deformities, and hip varus are sometimes not just bone problems, but are caused by other diseases.

Associate Chief Physician Chen Wenhao understands Xiuxiu's postoperative situation
What both experts are pleased that under the relay diagnosis and treatment of the two disciplines, the disease that may deprive the child of his life has been cured and the bone density has also begun to recover. The first hip correction surgery has been performed, and after another operation, he is expected to live like a normal child.
A broken bone was broken when he fell. It was not easy to check the problem when he went to the hospital.
Xiuxiu looked pretty and generous, and she smiled sweetly, sunny and friendly. She is usually very confident, but is not satisfied with her leg shape. She is the O-shaped legs in everyone's eyes. Since last summer vacation, her legs have been painful from time to time. In October, she accidentally fell and went to a nearby hospital for examination and found that she had multiple fractures and muscle strains . After treatment, I thought I could recover after a while of rest, but the pain from my legs from time to time told Xiuxiu's family that something was wrong.
In order to find out the cause, in March this year, Xiuxiu and her parents went to a large hospital closer to their home for treatment. After femoral biopsy, the doctor diagnosed Xiuxiu with bone fiber structure . Can I return to normal after surgery? Things didn't go that smoothly.
"Later, when I was in the hospital for color ultrasound examination, I found that my parathyroid had a tumor. My parents used to work in Hangzhou, and they thought Zhejiang University Children's Hospital was relatively strong, so they took me from my hometown." Xiuxiu, who has a lively personality, told her experience in an orderly manner.
In late March, Xiuxiu and her family went to the outpatient clinic of Chief Physician Wang Jinhu, oncology surgery. Seeing Xiuxiu sitting on the cart and being pushed into the clinic by her mother, Director Wang Jinhu, who has rich clinical experience, suspected that the problem was not simple.
Xiuxiu was soon admitted to the oncology surgery ward. X-rays found that in addition to parathyroid tumors and double hip deformities, Xiuxiu, who is only 13 years old, has osteoporosis throughout her body and the bone density of the bones throughout her body is abnormal. Xiuxiu is 13 years old. Why is she osteoporosis at a young age and is so severe that her bones dissolve?
The expert of the school in the ward has stripped the cocoon to determine the cause, and the "culprit" was removed by one-size-fits-all
Chief physician Wang Jinhu launched solid tumor MDT for her, and asked the radiology, pathology, pediatric gynecology, orthopedics, endocrinology and other disciplines to hold a multi-disciplinary discussion on Xiuxiu's condition.
Xiuxiu's situation is obviously not a simple poor bone fiber structure. Is her systemic bone problems caused by parathyroid adenoma? Her age is the age of multiple endocrine diseases. Is it MAS syndrome (peripheral precocious puberty accompanied by multiple bone cystic fibrosis and flaky brown pigmentation of the skin)? After discussion, the experts finally ruled out the possibility of MAS syndrome because her symptoms are still very different from the disease.
As the discussion deepened further, experts finally unanimously identified the cause as parathyroid tumor. "This child has multiple fractures throughout the body, and the bone density of the whole body is severely abnormal, causing the whole person to break as soon as he touches it like glass. We must consider the endocrine abnormalities caused by the tumor, which leads to abnormal bone density. In addition, this child found a parathyroid tumor on the neck, and we must highly suspect that the whole body bone problems were caused by parathyroid tumors." Chief physician Wang Jinhu analyzed.
"Usually, the human body has 4 parathyroid glands that secrete parathyroid hormone .Parathyroid hormone is actually very important. Secreting moderate amounts is beneficial to bone formation, but if it is secreted too much, it will harm the bone. It will promote bone calcium to dissolve into the blood and cause bone decalcification. The symptoms are mainly manifested as bone pain , prone to pathological fractures, leading to bone deformities, etc. "Associate Chief Physician Chen Wenhao added. After full discussion, the expert team locked in the "culprit": parathyroid tumor in the neck. After clarifying the cause, the oncology surgery and orthopedic team began to relay, and prescribed the right medicine to Xiuxiu in stages and steps.
In early April, Wang Jinhu, chief physician of Oncology Surgery, took the lead in surgery to remove the parathyroid tumor for Xiuxiu, and the operation went very smoothly. Postoperative examination showed that Xiuxiu's indicators gradually normal and blood calcium decreased significantly. After a period of supplementation of calcium and vitamin D, her bones The quality has also improved, close to the level of ordinary people.
distressing hip deformity has also been treated with orthopedic experts' osteotomy treatment
0 The tumor was removed. The bones were normal and the legs were no longer hurt. However, the leg deformity problem that made Xiuxiu distressed still exists.
"After the parathyroid tumor is removed, the bones will gradually recover, but the deformity caused by the early stage, namely, severe O-shaped legs caused by hip vocalization , can only be corrected through surgery and cannot be improved or recovered by itself. "Associate Chief Physician Chen Wenhao said.
Xiuxiu's double hip valgus is relatively serious. The hip of ordinary people is about 125 degrees, but Xiuxiu's hip valgus is more than 70 degrees, which greatly affects her daily life. This means that Xiuxiu will have to undergo two major surgeries.
"Considering that Xiuxiu is young, if both sides of the surgery are corrected at the same time, the surgery will be too trauma for her. Therefore, we decided to do the left first and then correct the right next time she came over. "Deputy Director Chen Wenhao said.
The surgery was performed by Deputy Chief Physician Chen Wenhao of Orthopedics, which was very smooth. Shortly after the operation, Xiuxiu returned to her former liveliness.
Mother breathed a sigh of relief: "We ran over thousands of miles to treat the disease. Now her tumor has been cut off and her legs have been corrected. This trip is worth it! "
Doctor reminds: Severe deformities in the legs or abnormal bone density, it is recommended to go to the hospital as soon as possible to check
" Early identification of parathyroid tumors is very important. If early diagnosis and effective treatment can be carried out, not only can the tumor be removed early, but the fractures and skeletal deformities will not be so serious, and may be immune to the pain of two osteotomy treatments. "
Chief Physician Wang Jinhu reminds: If the child is diagnosed with osteoporosis, bone fiber structure, or is particularly prone to fracture at a young age, "the whole person will break when touched". It is recommended to check blood calcium and do neck ultrasound.
Deputy Chief Physician Chen Wenhao reminds: For different degrees of hip deformities, exercise, massage correction, gypsum or stent fixation, surgical surgery and other methods can be adopted. It is crucial to detect problems early. If the child is found to have serious deformities in his legs, he should still go to the hospital as soon as possible to clarify the cause.
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