The normal physiological functions of the brain also rely on good blood circulation. If the cerebral blood vessels are partially blocked, it may cause blood circulation disorders, which may lead to stroke.

2024/11/0423:49:33 regimen 1324

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Only by continuous flow of blood in the human body can the normal operation of various tissues and organs be maintained. The normal physiological functions of the brain also rely on good blood circulation. If the cerebral blood vessels are partially blocked, it may cause blood circulation disorders, which may lead to stroke . So what drugs can help improve cerebral blood circulation and restore brain function?

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Early restoration of blood circulation in the ischemic area of the brain is the most effective and important measure in the treatment of stroke1. There are many methods for improving cerebral blood circulation, such as using thrombolytic drugs , drugs to improve cerebral collateral circulation, antiplatelet drugs, anticoagulants, etc.2,3,4.

Thrombolytic drugs

Thrombolytic therapy can quickly restore the blood supply to the ischemic area of the brain. Methods of thrombolysis include intravenous thrombolysis and arterial thrombolysis. Intravenous thrombolysis is to inject a thrombolytic drug into the vein to dissolve the thrombus blocked in the blood vessel; arterial thrombolysis requires insertion into the femoral artery in the thigh. A thin catheter delivers the drug directly to the thrombus through the arterial catheter to dissolve the thrombus. Thrombolytic drugs include alteplase , tenecteplase and urokinase etc.

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Drugs to improve cerebral collateral circulation

Cerebral collateral circulation means that when the "main road" blood vessels of the brain are blocked, the blood flow can reach the cerebral ischemia through other "auxiliary road" blood vessels, saving the damaged brain tissue, thereby promoting the recovery of brain neurological function. Commonly used drugs of this type include , butylphthalide, , etc.

Antiplatelet drugs

Antiplatelet drugs mainly reduce platelet aggregation or inhibit platelet activation through various ways to combat the formation of thrombus, thereby improving cerebral blood circulation and reducing the recurrence of stroke. Commonly used drugs include aspirin, clopidogrel, ticagrelor, etc.

Anticoagulant drugs

Anticoagulant therapy mainly inhibits certain coagulation factors in the blood coagulation process and prevents the blood coagulation process to achieve the purpose of preventing and treating thrombosis. Commonly used anticoagulant drugs such as unfractionated heparin, low molecular weight heparin, warfarin, etc.

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Other

include antifiber drugs, volume expansion drugs and vasodilators etc. For some patients with hyperfibrinogenemia, the use of fibrinogen drugs can reduce fibrinogen and prevent thrombosis from forming and expanding. Commonly used anti-fibrosis drugs include defiberase , batroxobin , etc. For some stroke patients with insufficient blood volume, cerebral blood volume can be increased by infusing some volume-expanding drugs, such drugs include dextran, hydroxyethyl starch, etc.

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Summary

It should be noted that the type, cause, and incidence of stroke are different. There are many drugs to improve cerebral blood circulation, and the indications and contraindications of the drugs are also different. Therefore, drug treatment must be carried out under the guidance of a doctor. .

References:

1. Chinese Medical Innovation, 2019,16(18):164-167.

2. Miao Zhongrong, Stroke Comics[M], People's Medical Publishing House.

3. Stroke Prevention and Treatment Guidelines (2021 Edition).

Note: Original article, please do not reprint without authorization! Cover/text image source: Photo Network. The images in this article belong to the copyright owner. If you need to use them, please contact the copyright owner directly.

Warm reminder: Popular science articles do not provide professional diagnosis and treatment opinions. Specific diagnosis and treatment should be carried out under the guidance of professional doctors.

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