[Source: Changde First People's Hospital]
The process of a pair of sperm and eggs, from cultivation to gestation into a new life in a small glass vessel, is the testimony of Huang Kaishu's exploration in the field of assisted reproductive medicine.
From the establishment of the Reproductive Medicine Center of Changde First People's Hospital in 2002 to the maturity of IVF technology today, Huang Kaishu leads a 26-person reproductive medicine team to bring good pregnancies to thousands of families and help thousands of parents give birth to new lives.
"As long as there is 1% hope, you have to put in 100% effort." As the director of the Reproductive Medicine Center of Changde First People's Hospital, Huang Kaishu devotes all her efforts to allowing infertile couples to have a good "pregnancy" companion and enjoy pregnancy. The beauty of life.
A "pioneer" who fills the gap in assisted reproduction
She was originally in the obstetrics and gynecology department, and the work was at her fingertips, but she suddenly turned to the unknown field of assisted reproduction. No one expected that Huang Kaishu's highly questionable decision 22 years ago would open the door to leadership in the field of assisted reproductive medicine in hospitals and open the window for "happy pregnancies" for thousands of families in northwest Hunan.
Huang Kaishu, director of the Reproductive Medicine Center, discusses the condition with colleagues in the department
Huang Kaishu graduated from Xiangya Medical College of Central South University in 1987 and has been working in the Obstetrics and Gynecology Department of Changde First People's Hospital since graduation. In 2000, few hospitals across the country carried out assisted reproduction. Out of curiosity about the new technology, Huang Kaishu went south to Guangdong to study at the Affiliated Hospital of Sun Yat-sen University. Facing the professor's English questions, Huang Kaishu secretly made up her mind to master the IVF technology.
has only three months of study time, and Huang Kaishu is thirsty for knowledge. "When the professors were working, I carried a small notebook with me to record knowledge points at any time; during the lunch break, I spent time in the archives room looking through cases, analyzing and comparing the massive cases, and finding out doubts; when I returned to the dormitory in the evening, I continued to organize them. Notes." Recalling that learning experience, Huang Kaishu gained a lot. After 3 months, she brought back 4 notebooks and read the technical operation procedures of test tube baby .
Returning to the hospital, Huang Kaishu was busy opening an infertility clinic, planning to build a reproductive center, and establishing an animal laboratory. In the early stage, a large number of mouse embryo tests and sperm survival tests needed to be done. She visited the clinic during the day and spent time in the laboratory at night, dealing with mice. She gave the mice ovulation induction injections, observed ovulation and fertilization, took out the fertilized eggs, and carried out the experiments in the laboratory. Doing mouse embryo culture…often overnight. "After people came out of the laboratory, they smelled like mice." Huang Kaishu recalled.
The hard work pays off. In February 2002, the Reproductive Medicine Center of Changde First People's Hospital was established. In August of that year, the second test-tube baby was successfully conceived. The hospital has filled a gap in the field of assisted reproductive medicine in northern Hunan, and Huang Kaishu has become a "pioneer" in filling this gap.
The 100-day-old dragon and phoenix test tube babies returned "home". Director of the Reproductive Medicine Center Huang Kaishu (left) and head nurse Gong Yuhua (right) held the twins.
From the establishment of the Reproductive Medicine Center, in 2008, the "test tube baby" technology was officially approved. In 2010, the center successfully passed the review by the Ministry of Health at that time, and Changde First People's Hospital became the only professional institution in northwestern Hunan that passed the acceptance by the Ministry of Health expert group and was approved to implement in vitro fertilization-embryo transfer (test tube baby) technology. Submit a dazzling report card to the whole society -
In May 2003, the first test-tube baby was born in northwestern Hunan;
In February 2004, the first artificial insemination baby with husband's sperm was born;
In January 2005, the first test-tube baby was born in northwestern Hunan The first intracytoplasmic sperm microinjection baby was born;
In September 2005, the first multiple-reduction in vitro fertilization baby was born;
In December 2011, the first vitrification-frozen test tube baby was born;
In January 2014, the first baby was born A test-tube baby was born using triple freezing technology.
started from scratch and competed with thousands of sails. Under the leadership of Huang Kaishu, the Reproductive Medicine Center of Changde First People's Hospital has become a professional reproductive medicine diagnosis and treatment center with strong strength, advanced equipment and rapid development in northwest Hunan.
The "yellow mother" who has given birth to children to millions of families
The beauty of pregnancy is the beauty of life, and even more so, the beauty of human nature.
The ordinary expectations of countless families, but it is the unspeakable pain of families who cannot naturally conceive . "The incidence of infertility is increasing year by year, and in recent years the incidence rate has been as high as 15%. In other words, out of ten families, there may be one or two infertile families." Huang Kaishu said that infertility It refers to the situation where the couple has a normal sexual life and does not take contraceptive measures for one year after marriage, but does not become pregnant.
In order for the patient to successfully conceive, Huang Kaishu does everything personally and meticulously, from planning, ovulation induction, ovulation monitoring, triggering, to egg retrieval, embryo culture, and transplantation. "IVF is not 100% successful. Every case is different. We must adopt an individualized treatment strategy and strive for excellence in every aspect without making any mistakes. Only in this way can we obtain the maximum and optimal treatment results." Huang Kaishu said.
In 2002, the hospital established the first reproductive medicine center in northwest Hunan, taking the lead in developing in vitro fertilization technology and attracting patients at home and abroad.
Embryo transfer is the key to the success of in vitro fertilization. In the past, when transplantation could not be performed under ultrasound, Huang Kaishu carefully judged the angle of the patient's uterus every time, and performed a pre-transplantation before entering the IVF procedure to predict possible situations and the direction of transplantation. , depth, and location to ensure first-time success.
From its establishment to today, the Reproductive Medicine Center of Changde First People's Hospital has brought new life to thousands of families and lit up new hope. Especially since 2016, the center's development has been on a fast track, with an average of 1,000 egg retrieval cycles per year, and the assisted reproductive success rate has reached the domestic advanced level. In 2020, it passed the review of the Provincial Health Commission and obtained the third-generation test-tube baby preparation qualification. Through the third-generation test-tube baby technology, genetic testing and screening are performed before embryo implantation, so as to block genetic diseases for patients in advance and give birth to healthy babies. child.
Although most patients can successfully conceive through conventional treatment plans, there are still many "difficult and complicated diseases". Facing challenges one after another and looking at the patient's gloomy face, Director Huang Kaishu often said, "When you get here, you must cooperate with the treatment. As long as there is 1% hope, we will not give up on you, and you can't give up either!"
There once was a patient who had never had a period in his twenties. He was sent to many hospitals and was diagnosed with "congenital uterine dysplasia" and told that there was almost no possibility of natural pregnancy. Although her family and she believe that it is impossible to have a baby of her own in this life, she still feels lonely every time she sees her friends showing off their babies happily and warmly. By chance, she learned about the Reproductive Medicine Center of Changde First People's Hospital, and with the mentality of giving it a try, she found Director Huang Kaishu. After the director carefully examined her, he found that she not only had an immature uterus, but also had ovulation disorder, which was undoubtedly another difficulty in her pregnancy. Director Huang Kaishu adhered to the medical principle of "never give up" and carefully treated her for a year. She used drugs to promote uterine development and make the uterus close to normal uterine size, which provided better "soil" for embryo implantation. However, a new problem arose. During the IVF process, her ovaries did not respond well to the drugs. Generally, the follicles of and of a patient can grow and mature in an average of more than 10 days after ovulation induction. However, her follicles were still immature more than 20 days after taking the drug. Huang Kaishu led the reproductive team, actively analyzed the reasons, constantly adjusted the diagnosis and treatment plan, and finally transplanted a good embryo "seed", allowing the " iron tree to bloom." The patient successfully conceived, and the family was extremely happy. "As long as Dr. Huang doesn't give up on me, I won't give up on myself!" The patient was so excited that he was beyond words.
The road to finding a child is full of hardships. Director Huang Kaishu remembers a patient who had both fallopian tubes removed due to two ectopic pregnancies and had to choose in vitro fertilization treatment. From her 20s to her 30s, she visited many reproductive hospitals in Changsha and had 4 egg retrievals and multiple transplants, but she failed to conceive. "The money I spent on IVF in the past eight years can buy a luxury car." She said when she found Director Huang Kaishu with a glimmer of hope through a friend's introduction.Indeed, the process of multiple ovulation induction, egg retrieval, embryo culture, and embryo transplantation not only makes patients and their families physically and mentally exhausted, but also places a heavy financial burden on infertile families. Doctors are kind-hearted. Director Huang Kaishu carefully read through the treatment information of this patient's multiple IVF cycles in other hospitals, and felt more and more that this patient was really not easy - repeated implantation failures, poor embryo quality, and difficulty in transplantation troubled a woman. What a happy and wonderful 8 years. Through discussions within the department, Director Huang Kaishu led the reproductive team to accurately identify the reasons for her repeated implantation failures, and gave a targeted and individualized treatment plan to protect the patient's journey to have a child, and ultimately made the patient successful. Take the baby home.
Gradually, each patient let go of their worries, cooperated with the treatment, and successfully conceived. The reputation of the Reproductive Center of Changde First People's Hospital spreads from person to person, attracting many patients from Henan, Jiangxi, Guangdong and other places, and even from abroad. Huang Kaishu became the "Huang mother" who sent children to thousands of families.
The "good big sister" who guides the new apprentices step by step
"We must have a sense of awe. When sperm and eggs are taken out from the body, we must maintain their original vitality and development potential." Zhang Wenquan, deputy director of the center, told the author that Huang Kaishu often expressed his gratitude to the team. What he said was still ringing in his ears. Never abandon, never give up, and respect life have become the professional beliefs that the medical staff of the Reproductive Medicine Center have always abided by.
At Changde First People's Hospital, "test tube baby" technology, artificial insemination, multiple pregnancy reduction, egg and embryo vitrification and other technologies are all mature, but in order to pass on these technologies, a team must be led. Huang Kaishu has strict requirements for this team and trains it in an echelon.
Laboratory staff are freezing embryos
"Doctors cannot conduct experiments on patients. Each doctor must complete 100 experiments to meet independent operating standards." Tang Bin, deputy director of the Reproductive Medicine Center, said that Huang Kaishu is particularly devoted to the training of young doctors. He worked hard and taught without reservation, allowing them to compare cases one by one in practice, conduct on-site analysis and guidance, and teach by words and deeds. "Many reproductive medicine centers in China operate on an assembly line, and one doctor can only operate one link. The doctors we train can operate the entire process of IVF. When we first started retrieval, Director Huang took care of us one by one. She is our good sister.” Tang Bin said that under Huang Kaishu’s leadership and training, the team of the Reproductive Medicine Center has grown from an initial team of four to a team of 26, including 10 doctors.
Huang Kaishu is devoted to her work, treating patients and leading the team, but she rarely takes a break. If a string is stretched for a long time, I often suffer from insomnia. "Both my husband and I are doctors, and we are usually busy with work. Until my daughter has grown up to be a doctor, looking back, we were absent during the child's growth stage. During the schooling stage, I only attended my daughter's senior year of high school once. Fortunately, my daughter is used to it, especially after becoming a doctor, and she understands us better." Huang Kaishu said that she is a doctor and it is her duty to help infertile couples realize their "dream of children." location.
Author | Publicity Department Comprehensive
Editing and Photography | Huang Ruifeng Ouyang Wen
Proofreading | Wu Mengqi
Review | Xiong Ni Leiyun
Final Review | Chen Ying
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