With the acceleration of the pace of life and work pressure, modern people generally have great psychological pressure. In 2019, there were more than 95 million patients with depression in China, with a lifelong prevalence of 6.9%, and female patients account for more than 660% of the total number of patients. How to improve psychological stress and reduce depression ? Dietary interventions, such as probiotic therapy, may be considered. Jiangnan University Wang Gang's team found that probiotics can relieve mental symptoms and comorbid gastrointestinal symptoms in patients with depression. Probiotics regulate the 5-serotonin energy system has been proven to be a key mechanism for its beneficial effects on the brain and intestines.
1. There are too many patients with depression!
As the pace of life and work accelerates, there are more and more patients with mental illness in China, and currently there are nearly 100 million patients with depression! Depression not only affects work and family, but also significantly increases the risk of self-harm and suicide, and requires active response. Dietary intervention can also be considered when consulting a psychiatrist and taking medication reasonably.
2. Probiotics can improve depression
Because patients with depression often have gastrointestinal abnormalities, such as intestinal peristalsis dysfunction, Wang Gang's team at the School of Food of Jiangnan University in China explored the improvement of depression through probiotics. They used compound probiotic preparations (including three probiotic strains of Bifidobacter brevis CCFM1025, Bifidobacter longus CCFM687 and Pilocon Lactate CCFM6432) to conduct clinical comparison observation and mouse experiments with 40 patients with severe depression.
Study found:
1. Compared with placebo, probiotics significantly reduced the depression score of patients with MDD (major depression)
2. Probiotics significantly improved the gastrointestinal function of patients;
3. Probiotic intervention improved the intestinal tract of patients with MDD (major depression) MDD (major depression) . Fungal flora , such as increased abundance of rumencoccals;
4. In mouse studies, it was found that probiotics significantly reduced the depressive behavior of mice and improved intestinal peristalsis;
5. The beneficial effects of probiotics in intestinal brain are related to their regulation of serotonin (serotonin). The serotonin transporter gene (Slc6a4) in the mouse model colon was overexpressed, and probiotic intervention reduced Slc6a4 expression, thereby maintaining normal levels of 5-hydroxytryptamine .
So, in order to reduce psychological stress and improve depression, nutritional intervention methods such as probiotics can be considered at the same time as routine treatment, which may have better results.
#Health Big V Creation Camp# #Health Knowledge Popular Science# #Probiotics#
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