Recently, many places across the country have successively launched the second dose booster vaccination of new coronavirus vaccine . As the number of people with "positive symptoms" and "positive health" continues to increase, which groups need to receive the second dose of "booster shot"? Can I get vaccinated after I have passed the sun? Xinhua News Agency reporter interviewed Solodan, director of the Institute of Immunization and Prevention at the Beijing Center for Disease Control and Prevention.

asked:
took the "third shot", why does he need to take the "fourth shot"?
Answer:
After being vaccinated with new crown vaccine , the level of neutralizing antibodies produced by vaccine has declined over time, and the protective effect against infection has dropped significantly. However, under the action of cellular immunity , a high protective effect against severe illness or death can still be maintained.
After the fourth injection, can activate the immune system in a short period of time and regain high-level neutralizing antibodies against the new coronavirus variant strain. further improves the protective effect of the vaccinated population in preventing infection, severe illness and death, and better improves protection capabilities.
Question:
Who can get the second dose of "booster shot" at this stage?
Answer:
In accordance with the unified deployment of the country, will be strengthened in the first dose On the basis of immunization, the second dose of booster immunization is currently being carried out among people at high risk of infection, people aged 60 and above, people with serious underlying diseases and people with low immunity. The interval between vaccination and the first booster dose must be 6 months or more.
Question:
What vaccines can be given for the second dose of "booster shot"? Which combinations are recommended by the country as a priority?
Answer:
According to the national plan, all vaccines approved for conditional marketing or emergency use can be used for the second dose of booster immunization. Priority is given to sequential booster immunization, or the use of vaccines containing Omicron strain or vaccines with good cross-immunity against the Omicron strain for the second dose of booster immunization.
sequential boosting of immunity refers to the use of vaccines with different technical routes for heterologous boosting immunity. Previous studies have found that heterologous booster immunization with vaccines using different technical routes can obtain higher levels of neutralizing antibodies than homologous booster immunization.
Currently, there are four types of new coronavirus vaccines that have been approved for emergency use or conditional marketing in my country: inactivated vaccine , recombinant protein vaccine , adenovirus vector vaccine and influenza virus vector vaccine . In general terms, as long as the vaccine type is different from that of the previous doses, it falls within the category of sequential immunization. Taking into account the actual situation that most of the recipients used three doses of inactivated vaccine during the early mass vaccination process in our country, for the second dose of booster immunity, you can choose any one of the recombinant protein vaccine, adenovirus vector vaccine or influenza virus vector vaccine, which is also the vaccination combination recommended by the country.

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Question:
How long does it take to vaccinate the second dose and the first dose of "booster"?
Answer:
According to the national plan, the time interval between the second dose of and the first dose of booster immunization currently implemented is html more than 16 months. The vaccination interval is usually determined after taking into account many factors such as the persistence of vaccine antibodies, the decline in vaccine protective effect, the risk of reinfection, and the epidemic situation.
Question: Can I get vaccinated during
positive period? How long does it take to get vaccinated after being positive?
Answer: There is no need to vaccinate during the positive period of
, because the function of the vaccine is to prevent the disease and has no therapeutic effect. According to the country’s current technical guidelines for the use of new coronavirus vaccines, reinfection is rare within 6 months after a positive infection with the new coronavirus. Those who have been infected with the new coronavirus, including patients or asymptomatic infections, can receive one dose after 6 months after being fully informed.
Question:
Why is it recommended that the elderly receive a second dose of "booster"?
Answer:
The elderly are a high-risk group for severe death due to infection with the new coronavirus, and are also the main group for severe death after infection with virus . Both foreign data and data from Hong Kong, our country, show that the case fatality rate can be significantly reduced after the elderly people receive the booster shot. After receiving the second dose of the booster shot, the case fatality rate can be further reduced. By receiving the second booster dose, the elderly can increase their antibody levels in a faster time and better enhance their protective capabilities.
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Source: Xinhua News Agency, People’s Daily, etc. (The cover image comes from the Internet and has nothing to do with the content of this article)