A recent study published in the journal Pharmaceutical Epidemiology and Drug Safety showed that between 1999 and 2017, the proportion of drugs that can increase the risk of falling in the United States increased from 57% to 94%.

2025/07/0802:41:36 hotcomm 1066

Source: [Life Times]

Department of Pharmacy in Wuhan Central Hospital Clinical Pharmacist Li Yuanyuan

For special groups, especially the elderly, even minor falls are dangerous. Severe cases such as hip fracture and head trauma can even endanger life. A recent study published in the journal Pharmaceutical Epidemiology and Drug Safety showed that between 1999 and 2017, the proportion of drugs that can increase the risk of falling in the United States increased from 57% to 94%. During the same period, the mortality rate of elderly people caused by falls increased by more than 100%.

A recent study published in the journal Pharmaceutical Epidemiology and Drug Safety showed that between 1999 and 2017, the proportion of drugs that can increase the risk of falling in the United States increased from 57% to 94%. - DayDayNews

Judging from the more than 7.8 billion prescriptions filled in by elderly people in the United States, drugs that increase the risk of falling mainly include the following 7 categories:

1. Antidepressant drugs, such as imipramine, amitriptyline . This type of medicine can cause orthostatic hypotension, , dizziness, as well as sedation, drowsiness, blurred vision, etc. These adverse reactions can easily cause patients to fall.

2. Antihypertensive drugs, such as losartan , terazosin . When blood pressure is lowered, the human body's hemodynamics will change, and sometimes orthostatic hypotension will occur, resulting in adverse reactions such as drowsiness, headaches, and dizziness.

3. Strong opioid analgesics, such as morphine and petidine. This type of medicine can stimulate the chemoreceptor area of medullagen and emetic vomiting, and increase the sensitivity of vestibular organ , leading to dizziness, nausea, vomiting, causing orthostatic hypotension, and then drowsiness and unstable gait.

4. Sedative hypnosis drugs, such as diazepam (validum), nizopam, eszolam (sulaxadim), alprazolam, etc. This type of medicine will inhibit of the central system of , which can cause adverse reactions such as drowsiness, dizziness, fatigue, and ataxia (the loss of control of human balance, manifested as posture, gait and language disorders).

5. Low glycemic drugs, such as glibenclamide, glipizine , reglinide , and insulin preparation. If a patient develops hypoglycemia after taking the medicine, it will affect consciousness, mental, visual, physical balance, etc. to varying degrees.

6. anti-allergic drugs , such as promethazine , ketotifen , chlorphenamine (also known as chlorphenamine, including cold medicines containing this ingredient). This type of medicine can cause drowsiness, sedation, fatigue, and increase the risk of falling.

7. Diuretics, such as furosemide, spironolactone. Patients need to go to the toilet frequently after taking it. If the body loses a large amount of body fluids and electrolytes in a short period of time, they will experience drowsiness, fatigue, dizziness, unsteady walking, and fall.

If the elderly are taking the above-mentioned "falling" medicine, the following points should be paid attention to:

1. Within 1 hour of taking this type of medicine, the patient should get up and sit slowly. When the patient suddenly turns from the lying position or sitting position to the standing position, symptoms such as dizziness, mild headache and even fainting may occur. At this time, the patient should continue to lie down and sit for a moment before standing, to prevent the symptoms from happening again. 2. Pay attention to the way of taking the medicine. For example, it is recommended to take terazosin before going to bed. 3. After taking anti-glycemic drugs, you should eat on time and carry carbohydrate foods with you. If you experience hypoglycemia, you can eat them immediately. 4. For elderly people who take diuretics for a long time, it is best to take medication before 4 pm to avoid frequent urination of at night, and should go to the hospital for electrolyte testing regularly. 5. It is recommended that people who take these drugs for the first time should not drive vehicles, operate machinery or operate high altitudes within 12 hours or when the dose increases. 6. Be sure to take the medicine regularly and regularly as per doctor's instructions. Do not add the medicine without authorization. Try to use the medicine as single as possible to avoid the combination of multiple drugs. If you really need to use it together, you should strictly follow the doctor's instructions to reduce the amount as appropriate.

This article comes from [Life Times] and only represents the author's views. National Party Media Information Public Platform provides information release and dissemination services.

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