As the new crown vaccination is rapidly rolling out
I believe many friends have finished the first shot
A netizen who feels that he has "never poisonous" proudly designed a T-shirt
The sleeves are written:
The first shot is passed quarantine SR
The second shot is passed quarantine SR
The second shot is passed quarantine SSR
Use the rarity of the game to describe the vaccination process, of course, it is just a joke
However, on the days when I was waiting for the second shot, I was curious about the baby posed new questions in a fancy way
00. The Shanghai Health Commission sorted out 9 of these questions yesterday
made a systematic authoritative reply:
01
Is there any difference in the ingredients and dosage of the two shots of the new crown vaccine?
Answer: According to the current immunization strategy, there is no difference in composition and dosage between the two doses of the new crown vaccine, whether it is the first or the second shot.
Currently, the city uses the new crown vaccine produced by the Wuhan Institute of Biological Products (Wuhan Institute), Beijing Institute of Biological Products (Beijing Institute) and Beijing Sinopharm Zhongwei Biotechnology Co., Ltd. (Beijing Sinopharm Zhongwei). The above three vaccines are all inactivated vaccine , and the production process is basically the same.
02
Can the new coronavirus vaccine from different manufacturers be replaced by vaccination?
Answer: According to the "Technical Guidelines for the Vaccination of New Coronavirus (First Edition)", it is recommended to use the inactivated COVID-19 vaccine from the same company to complete the full vaccination process. If the vaccine cannot be continued to be supplied, the recipients are vaccinated from other places, and the full vaccination process cannot be completed with the inactivated COVID-19 vaccine from the same company, the vaccine products of other manufacturers of the same type can be completed.
03
001 vaccinated with a new crown vaccine in other places. Can I still get a second shot in Shanghai?
Answer: I have received an injection and now I have returned to Shanghai. You can complete the subsequent dose vaccination according to the vaccination records from other places according to the arrangement of the vaccination site (the interval between 2 doses of the inactivated new coronavirus vaccine is recommended to be ≥3 weeks, and the second dose is completed as soon as possible within 8 weeks). For those who have not completed vaccination according to the procedures, it is recommended to re-swer as soon as possible. At this stage, it is recommended to complete vaccination with the same vaccine product, but if the vaccination cannot be completed with the same vaccine product, the subsequent dose of vaccination can be completed using vaccine products from other manufacturers of the same type.
04
What happens if you don’t get the second shot?
Answer: The determination of the immunization procedure of the vaccine is based on the results of the R&D and clinical trial stages to obtain the best safety, immune response effect and immune durability. Without completing the full vaccination, it is difficult to obtain the best immune response effect and immune durability.
05
After the first injection is finished, is it important to make an appointment for the second injection temporarily?
Answer: Currently, the best vaccination interval between the second dose of the vaccine is recommended between 3 and 8 weeks. The vaccination site will reasonably arrange the vaccination time of the second dose based on the vaccine supply and the time of each person's first dose. If you can’t make an appointment for the time being, don’t worry, because the results are guaranteed within the 3 to 8 weeks range. Please wait patiently.
06
After the first injection, symptoms appear. Can I still get the second injection?
Answer: Let’s list several situations.
The first type is after vaccination, which happens to catch a chronic disease or suffers from acute diseases such as colds and herpes. For this kind of situation, the disease should be controlled and treated first. When the onset period is over or the chronic disease is controlled stably, you can continue to receive the second dose.
The second type is that after the first dose of inoculation, there are adverse reactions such as fever and mild rash. From the results of the clinical trials of the new crown vaccine and the information collected during the use of the new crown vaccine, the occurrence of common adverse reactions to the new crown vaccine is basically similar to other vaccines that have been widely used. It mainly involves redness, swelling, nodules, pain, etc. at the vaccination site, as well as fever, fatigue, nausea, headache, muscle aches, etc. Usually this type of reaction will disappear on its own over time without special treatment, and the second shot can also be vaccinated as usual.
vaccination taboos include:
(1) Those who are allergic to the active ingredients of the vaccine, any inactive ingredients, substances used in the production process, or those who have experienced allergies when they were vaccinated with the same type of vaccine;
(2) Those who have had severe allergic reactions in the vaccine (such as acute allergic reactions, angioedema, dyspnea, etc.);
(3) Those who suffer from uncontrolled epilepsy and other serious neurological diseases (such as transverse myelitis, Guillenbarre syndrome, demyelinating diseases, etc.);
(4) Those who are fever, or suffer from acute diseases, or those who are suffering from acute attacks of chronic diseases, or those who are uncontrolled severe chronic diseases;
(5) Women during pregnancy.
Of course, if you feel that you can’t take it for your own condition, you can tell the doctor at the vaccination site truthfully to let the doctor determine whether you can get vaccinated.
07
How long is the better time to be between two doses of vaccines?
Answer: It’s only been more than a year since the discovery of the new coronavirus, and research on the new coronavirus vaccine is also being updated. The "Technical Guidelines for the Vaccination of New Coronavirus Vaccination (First Edition)" issued by the National Health Commission on March 29, 2021 recommends that the vaccination interval for 2 shots of inactivated new coronavirus vaccine is 3-8 weeks (21 days to 56 days). The vaccination site will reasonably arrange the vaccination time of the second dose based on the vaccine supply and the time of each person's first dose.
08
In February and March last year, some vaccine developers had already received the new crown vaccine. What are the antibodies in these people?
Answer: In fact, the development of the new crown vaccine has been less than a year, and the data will be updated at any time as time goes by. In March last year, some people, as the "vanguard" of vaccines, had received the inactivated COVID-19 vaccine that has been launched. The vaccine companies carried out clinical monitoring and have obtained more than 9 months of antibody testing data so far. The data shows that the antibodies still maintain a certain level. Monitoring will continue to be strengthened in the future to further observe the maintenance time of the antibodies.
09
Can you please try to play later?
Answer: Only when the vaccinated individuals reach a certain proportion can the population be protected, that is, to form a population immune barrier to protect individuals who cannot be vaccinated due to vaccination taboos and other reasons, as well as a few people who have not yet developed protection after vaccination. If everyone delays the time for vaccination, then the immune barrier will never be established.
If everyone gets vaccinated quickly, this barrier may arrive one day earlier. To return to normal life as soon as possible, vaccines are the best choice at present.
But in fact, as the types of vaccines on the market become more and more abundant
I know you want to ask another question:
Which new crown vaccine is the best?
Among the currently several vaccines promoted globally, the Phase III clinical data of Pfizer/BioNTech, Moderna vaccine and Russia's "Satellite V" vaccine show that its effectiveness is more than 90%; the Oxford/ AstraZeneca vaccine is 62%-90%. The effective efficiency of Sinopharm Group vaccines that are being widely deployed in China is 79%, and Sinovac's vaccines are 50%-83%. The clinical data of the Phase III adenovirus vector vaccine developed by Academician Chen Wei's team of the Academy of Military Sciences and CanSino Biologics shows that the overall efficiency is 65.7%. These vaccines all exceed the WHO-recommended threshold for protection rates greater than 50% to market.
The vaccine efficiency mentioned above actually refers to "protective efficacy", that is, the protective effect of a certain vaccine on the disease in clinical trials, including whether it can prevent infection, reduce severe illness and even prevent death.
But this does not mean that the higher the protective efficacy of the vaccine in clinical trials, the better the effect in reality. Because the effectiveness data reflected by vaccines in different clinical trials will be affected by many factors, which also makes it difficult to directly compare different new crown vaccines.
For example, the patients counted by Sinovac vaccine are all patients above level 2 in the WHO Agreement, including those with only mild symptoms without medical intervention, that is, very mild symptoms. In Pfizer's clinical trials, it is counted for infected people who have been diagnosed with nucleic acid tests and have a symptom.
Secondly, the region, time and the strains that were prevalent at that time were also different in each vaccine clinical trial.This adds countless different variables to each experiment.
Data so far show that all vaccines on the market are much more effective than symptomatic treatment. Taking Sinovac vaccine as an example, its phase 3 trial in Brazil, one of the countries that are most affected by the new crown, showed that although the overall protective effect of the vaccine is 50.4%, its protective effect for severe COVID-19 and hospitalizations reaches 100%, which means that the vaccine can greatly reduce the chance of severe illness.
For vaccine developers, it is endless to pursue vaccines that are more efficient and safe, have lower adverse reactions and are more convenient to store and transport. But for decision makers, the most urgent task is to decide which vaccine can meet the needs of a larger range of people in the shortest time based on the actual performance of existing vaccines after they are launched.
"Vaccine hesitation" is a normal human nature. But the longer the hesitation, the longer the new crown will be. When people take off their masks to celebrate the end of the epidemic is directly related to the coverage of vaccination.
For individuals, no matter what technical route is used, as long as it is a vaccine officially approved for marketing by a national regulatory authority, its safety and effectiveness are supported by data. The public has the right to be vaccinated with confidence if the potential benefits or known benefits are greater than the potential risks or known risks.
If you have to ask, what is the "best" vaccine for
?
That is the one that
can hit your arm immediately.
This article is compiled from: Shanghai Release, I am a Scientist, iScientist, etc.
Source: Shanghai News Broadcast
