Everything editor: Wang Yuelong, Gai Yuanyuan
As the mutated new coronavirus Omickron continues to evolve subtype strains with higher infectiousness and concealment, the peak of epidemics in many countries has emerged repeatedly, and the level of virus infection continues to rise. What it brings is the uncertainty of the ongoing mutation of the virus, the health risks suffered by the public, the huge pressures borne by the medical system, and the multiple damages suffered by social life.
Among them, , Japan, html has increased on the 5th, exceeding 200,000 for the first time, and 47 , 22 of the prefectures and counties, hit a new high in the number of confirmed cases in a single day, and some areas have difficulty in testing and medical treatment.
As of the 22nd, the cumulative number of confirmed cases of new crown in the United States has exceeded 90 million, and the cumulative number of deaths has exceeded 1.025 million; the cumulative number of confirmed cases of French and in the United States has exceeded 30 million.
Japan's new confirmed cases of new coronavirus exceeded 200,000
Cabinet Chief Secretary confirmed to be infected with the new coronavirus
According to CCTV News, as of 17:40 local time on the 23rd, the number of new confirmed cases of new coronavirus in Japan nationwide was 200,975, exceeding 200,000 for the first time, setting a new high since the outbreak of the epidemic, setting a new record for the past four consecutive days. Among them, 17 first-level administrative regions hit a record high.

Image source: Xinhua News Agency/Reuters
As of the 23rd, the cumulative number of confirmed cases of new crown in Japan was 11212150, and the cumulative death toll was 31,877. Tokyo reported 34,995 new confirmed cases on the same day, exceeding 30,000 for two consecutive days, continuing to hit a new high.
According to the Japanese News Agency on the 23rd, Japanese Cabinet Secretary Hiroichi Matsuno was confirmed to be infected with the new coronavirus on the same day.
Japan's Ministry of Health, Labor and Welfare announced on the 22nd that it will invest in the prevention of the Omickron variant , and the fifth dose of vaccination will be launched after this fall.
According to Xinhua News Agency , at present, some testing institutions and fever clinics in Tokyo have been unable to receive treatment. Japanese Prime Minister Kishida Fumio 22 announced that he would issue antigen kits to patients in fever clinics for free, allowing people to test independently, and those with mild and asymptomatic symptoms should be isolated at home. On July 21, the Tokyo Metropolitan Government has raised the medical alert level to the highest level.
"Lying flat" in the UK has exceeded 200,000
According to Xinhua News Agency, the UK National Bureau of Statistics released a report on the 22nd that the latest weekly statistics showed that the UK had more than 3.76 million new confirmed cases of COVID-19, the highest single-week confirmed cases since mid-April.
The UK National Statistics Office pointed out that since the end of June, most cases in the UK have been infected with the mutated new coronavirus Omickron strain BA.4 or BA.5 subtype. In the week ended July 3, 89.2% of all the sequencing COVID-19 cases accounted for 89.2%.
The UK, which has "lying flat" in epidemic prevention, is one of the countries with the highest mortality rate for the new crown in Europe. The latest data from the UK's National Office for Statistics shows that the positive rate of COVID-19 tests in all parts of the country is increasing, with the number of new crown deaths exceeding 200,000 at the end of June.
Many new crown patients across the UK are facing the problem of "draw lots to treat" , and the services provided by the UK's national medical service system are "seriously insufficient". U Leicester University expert Christopher Breitlin said: "If there is no effective treatment, the long-term new coronavirus may become a highly prevalent new long-term disease."

Image source: Xinhua News Agency
According to the latest data released by the Robert Koch Institute, the German federal disease control agency, as of 0:00 on July 23 local time, Germany has a total of 30331,131 confirmed cases of new coronavirus pneumonia, 92,009 new confirmed cases compared with the previous day; the cumulative deaths are 143,177, 116 new cases compared with the previous day. The incidence rate per 100,000 people nationwide was 709.7 in 7 days.
Some experts believe that the "live-down" fight against the epidemic in Europe and the United States has increased the risk of new mutant strains. Richard Hatchett, CEO of , , said that as long as the virus spreads very high, as long as there are unprotected groups, it is possible to create an environment for viral mutation. Viruses will continue to evolve, and unpredictable viruses have the potential to cause a pandemic at any time.
Experts warn that the current major prevalent Omickron strain has evolved to be “very good at” escaping the immune response and triggering infection. Stephen Griffin, an associate professor and virologist at the University of Leeds School of Medicine, said the reinfection rate caused by mutant strains is also increasing significantly, highlighting the escape ability of mutant strains, and their rapid waves of infections around the world are worrying.
British media: Experiment found that the new coronavirus may enter the brain from the nasal cavity
According to the reference news website, citing the British "New Scientist" weekly website on July 20, the new coronavirus may enter the brain by establishing tiny channels from the nasal cavity.
reported that the new coronavirus is believed to be related to a series of neurological symptoms, including brain fog and confusion. The autopsy also found the new coronavirus in the brains of new coronavirus deaths. But how the new coronavirus enters the brain has always been a mystery. Previous studies have shown that unlike cells attached to the nasal cavity, mouth and lungs, the ACE2 receptor that the new coronavirus is usually used to enter cells is hardly detected in the brain.
Due to the lack of ACE2 receptor, human brain simulated cells themselves will not be infected with the new coronavirus. But when they incubate in the same dish, , with the nasal mimic cells that exist these receptors, the human brain mimic cells are infected.
Under a high-ratio electron microscope , researchers found that when the new coronavirus enters the nasal simulated cells, it stimulates the latter to grow tiny channels called tunnel nanotubes, forming connections with human brain simulated cells. After magnification showed the multiple, the researchers saw that the new coronavirus used these channels to travel between the two cells.
However, Munier said that since the experiment is limited to cells in the culture dish, further research is needed to confirm that the same mechanism exists in the human brain. Zurzolo said her team is conducting “organ chip” experiments that can more realistically mimic the interaction between cells in the nasal cavity and brain. If it can be confirmed that tunnel nanotubes transmit the new coronavirus from the nasal cavity to the brain, then we may be able to develop drugs to block them. She said: "At present, we do not have a specific molecule that can block tunnel nanotubes, but we are conducting screening and hope to find something."
edited by | Wang Yuelong Gai Yuanyuan
proofreading | Cheng Peng
Daily Economic News is comprehensive from Xinhua News Agency, CCTV News, Reference News
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