clinic, one of the most common questions asked by many female patients of childbearing age with severe psoriasis is: Doctor, can I get pregnant in my current situation? Will it affect my child? Can I prepare for pregnancy normally while taking the medication? Doctors often tell patients that they must use effective contraception during treatment with biologics and continue to use contraception for 6 months after stopping the drug.
The long-term safety of biologics in pregnant patients is currently unknown.
Some studies have found that the use of TNF-a inhibitors during pregnancy does not increase the risk of fetal death or miscarriage. However, recent small sample studies have shown that the use of TNF-α inhibitors during pregnancy increases the risk of miscarriage.
Therefore, it is recommended that pregnancy should be avoided during the use of biological agents. If pregnancy occurs during treatment, it is recommended to discontinue the drug. The latest British biologics drug instructions recommend that patients stop taking the drug before pregnancy, with varying intervals required. Furthermore, young children with a history of uterine exposure to biologic agents should not receive live vaccines within 6 months of life. Therefore, the long-term effects of biological agents on pregnancy still need to be observed.
