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Many oligonucleotide drugs require modifications where their phosphate bonds are connected to improve their absorption efficiency and stability (1). Oligonucleotide drugs usually need to be modified to improve stability and absorption efficiency (1). However, this also brings abo
Science | More flexible oligonucleotide synthesis
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The ten-year ban on fishing in the Yangtze River has initially yielded results. A large number of silver carp have appeared in the river, and the four major species of fish are also flourishing. However, with good news comes trouble, and the explosive growth of silver carp shows
The "Happiness and Worry" of the Yangtze River: A large number of wild silver carp appear in Zhenjiang. Why is the situation of anchovies so worrying?
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We are no strangers to shooting stars. After all, making a wish on a shooting star is a romance recognized all over the world, regardless of national boundaries and cultures. However, meteors generally occur at night. Have you ever seen a meteor phenomenon occur in broad daylight
A huge explosion was heard in the sky in the United States, and a large fireball flew past at a high speed of 24,587 meters per second.
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The advantages and disadvantages here are not necessarily the literal meaning of strength or weakness, but rather the ability to adapt to the natural environment. There are 1.4 billion people in China and more than 7 billion people in the world. So many people are not worth menti
Is it possible that being unmarried and infertile is eliminating inferior genes?
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An international team of astrophysicists studied the emergence of ion holes in Earth's magnetotail and assessed their impact on space weather. They found that ion holes propagate obliquely toward the local magnetic field. The results of this study will contribute to a better unde
Scientists can predict space weather more accurately
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1. Shale is a kind of [ ] rock, which is mainly formed from clay after a long period of deposition and subjected to a certain pressure and temperature. A. Sedimentation B. Metamorphism C. Magma Answer: A.
Summary of four-person competition rock questions
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Mount Fuji is not as "immovable" as it appears on the surface. It seems that a force is rapidly building up inside! Some experts believe that Mount Fuji may erupt at any time; other experts disagree, believing that people are over-interpreting the recent anomalies in Mount Fuji!
Is Mount Fuji in Japan safe? Chinese satellite unexpectedly discovered that the snow area on the top of the mountain has decreased by 61% in 4 years
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Chang'e-5 returned to Earth with "fresh" lunar soil samples. While we are still immersed in the joy of the lunar exploration project, NASA in the United States cannot sit still. Their director suggested that China share the soil brought back by Chang'e 5, just like they did with
NASA director made suggestion: China should share Chang'e 5 lunar samples, just like Apollo
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2022EHA Annual Meeting Mantle cell lymphoma (MCL) is a B-cell lymphoma with unstable genome and high mutation frequency. The characteristics of genomic instability are associated with repeated relapse and short progression-free survival (PFS) and overall survival (OS). related.
2022 EHA | The prognostic role of genetic abnormalities in patients with mantle cell lymphoma
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Let me ask you a very common sense question, can two different organisms have offspring? Without thinking about it, everyone will say no. Because of reproductive isolation, two organisms cannot produce offspring.
Five women were recruited for a crossbreeding experiment with chimpanzees. What was the result?
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Metaverse, an "old word" from thirty years ago, suddenly became popular in the post-epidemic era and continues to appear in the public eye. The universe sounds very sci-fi. If you want to understand the concept of the metaverse, you really have to find inspiration from science fi
Guangdong Future Technology | Metaverse = real world mapping + virtual world interaction
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Will the question of human origins and evolution be rewritten? If you want to ask, among the many disciplines, which discipline’s knowledge will be turned upside down every five years? Well, paleoanthropology is definitely on the list. Due to the archaeological evidence that pale
Human origin or being rewritten? Fossils reveal that humans may have originated in Africa. Is it an ancestor of the Chinese?
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Reuters, Washington, March 31 (Reuters) - The international scientific team Telomere to Telomere Consortium published the first complete, gap-free human genome sequence, revealing for the first time highly identical segmental repeat genomic regions and their role in the human gen
What does it mean for scientists to publish the complete human genetic sequence for the first time?
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Recently, the new variant of the Omicron strain BA.2.75 has attracted the attention of researchers from many countries. This new variant is a second-generation variant. Previously, there were types of Omicron strains such as BA.1, BA.2, BA.3, BA.4, and BA.5, all of which were fir
Lots of mutations and fast spread! The "second generation variant" of Omicron appears
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A mysterious animal appears in Hyogo Prefecture, Japan: a hairless animal with a long face. What is it? Let’s talk about Hyogo Prefecture first. It is not as famous as a big city like Tokyo, Japan, but it is the only one among all the prefectures in Japan that is connected to bot
A hairless, long-faced mysterious animal appears in Japan? Animal experts warn: Don’t get close and don’t touch them
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Highlights of technology commercialization Arzeda’s core technology value Arzeda has developed a protein design platform that combines computational design technology and artificial intelligence technology based on protein biophysics and metabolic biochemistry to support flexible
Protein meets AI, breaking through the boundaries between natural and chemical synthesis, and having unlimited application scenarios
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The Spring Festival is approaching, and the spirit of the New Year is getting stronger. Due to the epidemic in some areas, many places have repeatedly advocated "not returning to your hometown unless necessary" to encourage celebrating the New Year in situ. Recently, the Siming D
Good news! During the Spring Festival, these tourism companies in Siming can receive subsidies. For details, click →
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Dr. Dingxiang once posted on Weibo: A study showed that the rate of depressive symptoms among Chinese children and adolescents was 19.85%, and among children and adolescents in central China, this rate even reached 23.7%. In other words, one in every five children in China may ha
Why did children in the past rarely suffer from psychological problems despite being scolded and beaten? Worth pondering for countless parents
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Seventy-eight Gong Rui and Qin Yingying finished talking about dating their ex-wife. The two happily discussed the specific wedding date. Gong Rui initially planned to put it on November. Qin Yingying said: "That has to be discussed with my parents." Gong Rui smiled. "Of course,"
He and his mother went to propose marriage, and the woman’s family proposed renovating the house. Fortunately, his mother didn’t mention the house book.
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The heavy rain outside the window made Aunt Hong anxious. The old mother had just fallen asleep in the hospital bed, and the doctor told her to keep an eye on her all night. When her mother passed out in the afternoon, she was so panicked that she completely ignored her daughter
Xue Yingzhe丨Comparing one's heart with one's heart (short novel)
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Liu Changhong opened the courtyard door, and it turned out to be her husband's brother Sun Ruidong, who lived just across the wall. Sun Ruidong told her that her mother "can't survive." She hurriedly came to Sun Ruidong's home and found her mother-in-law Yu Fengqin lying on the g
Dreaming of "ascending to heaven", the son strangled his mother to death
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Previous episode: It would be great if she could fly out of the window like a bird. After a while, Li Zhanqiu came to him and took out a note from Liu Ruyi, saying that she was in danger and must be rescued immediately. Bai Tingsong carefully observed the surrounding environment
They made an emergency rescue late at night, but the person disappeared?
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