Research by the Hebrew University of Israel says that for the past half a century, men's fertility has shown a cliff-like decline and is still accelerating.
The research team led by Professor Hagay Levin published a paper in the journal Human Reproductive News that the latest research found that in less than 50 years, the average sperm count and sperm concentration in men around the world have dropped by more than 50%. The paper’s data covers 223 studies and more than 57,000 male samples from 53 countries. The data spans from 1973 to 2018. This finding means that the decline in male sperm concentration and quantity is a global problem.
In fact, last year, the article published by " Scientific American " pointed out that in the past few decades, there have been three adverse trends in male reproductive health problems: including a decrease in sperm count, a decrease in testosterone levels, abnormal increase in genital development in boys, and the "lowering" of erectile dysfunction (ED).
Studies have shown that from 2005 to 2017, the incidence of "not doing" for men under 40 years old increased from 13.5% to 21.7%.
In my country, ED is also a major killer threatening the reproductive health of Chinese men. Data analysis shows that the overall prevalence of ED in mainland China is as high as 49.69%, which affects the physical and mental health of nearly half of Chinese men and further poses a burden on family life and socio-economics.
It is worth noting that due to the common pathogenesis of ED and cardiovascular disease, erectile function problems are also potential warning signs of cardiovascular disease - may increase the risk of cardiovascular disease in the future and tend to increase cardiovascular mortality.
With the continuous growth and increasing youth of the incidence of ED, the sales of ED first-line therapeutic drug, sildenafil citrate tablets, has also increased year by year.
According to minenet , the release of the "Top 20 products of China's online pharmacies terminal chemical drugs in 2021" can be seen that the top of the list are actually the first-line treatment drugs for ED - sildenafil citrate tablets, which is what we commonly call "Viagra".
In October 2014, the pink small pill of Baiyun Mountain officially entered the ED market. From 2014 to 2021, Jinge's sales increased by 3,372 times, and a total of 320 million pieces were sold in seven years. The sales of
ED therapeutic drugs have doubled year by year, reflecting the gradual increase in the prevalence of ED in my country. But from another perspective, there is also a positive side.
In the past, once erectile function-related diseases occur, the patient immediately became nervous and had a deep psychological trauma, and even chose to avoid attitude, let alone actively treat. With the popularization of male health science and education, more and more men are beginning to face up to this disease. ED is not a disaster. Through active treatment and regular medication, sexual function can be effectively improved.
In addition, ED often coexists with male infertility (comorbidity). Sildenafil, which has a significant effect in treating ED, actually has a positive effect on improving male sperm quality. Studies have shown that PED5 inhibitors such as sildenafil can not only improve the vasodilation of male genitals, but also increase the blood supply and blood flow of the testicles. By opening up sperm, it forms signaling pathway , helping sperm generation and speeding up its swimming. After adding the PDE5 inhibitor to liquid nitrogen for frozen sperm, the sperm's vitality will increase by three to five percentage points compared to the original one.
Experts call for male reproductive health to be the cornerstone of family happiness. Whether it is male ED or infertility, patients who face these problems should seek medical treatment in a timely manner and adopt professional treatment plans to help raise healthy babies. They must not be afraid of medical treatment or believe in folk "folk remedies".
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