"The most important thing is that the theory of synthetic biology is likely to be born in Shenzhen." At the China Synthetic Biology Academic Annual Meeting in December last year, Academician of the Chinese Academy of Sciences Gao Fu said. Shenzhen City, especially Guangming District, takes synthetic biology and synthetic biology industry as a key discipline and pillar industry, "can be said to have grasped the direction of future development."
Guangming District, which "grasped the future" and is the youngest administrative district in Shenzhen. It was officially unveiled in September 2018. Shenzhen has given Guangming District the positioning and mission of "building a comprehensive national science center, pilot start-up area, building a world-class science city and a northern Shenzhen center."
Southern Finance All-Media reporter learned that Guangming has made a breakthrough in the construction of "0-1 (basic scientific research)". The next step is how to gather high-quality enterprises and help them continue to make breakthroughs in the direction of "1-10 (commercialization)" and "10-100 (industrialization)".
With the help of the spillover effect of the Guangming Science City large scientific installation, the biomedical track, information science and technology industries such as Guangming District synthetic biology research are standing on the eve of the industrial outbreak.
The original innovation of standing on the "shoulder of giants"
"If I see further than others, it is because I stand on the shoulder of giants." Newton 's famous saying is often used as a humble word for scientists. But in modern science, the "shoulder of a giant" includes both a good innovation and entrepreneurship environment and a powerful large scientific device.
Basic research is the source of the entire scientific system, and original innovation is the key to the level and ability of scientific and technological development. As the youngest administrative district in Shenzhen, Guangming District’s original innovative bull nose is a large scientific installation.
"The development of the economy and society depends on the support of infrastructure such as highways, high-speed rail, and electricity. Similarly, the development of science and technology innovation requires the support of major scientific and technological infrastructure. Once the innovative infrastructure is built, its spillover effect will be very high." Professor Sun Dongbai, director of Shenzhen Comprehensive Particle Facilities Research Institute, told the reporter of Southern Finance and Economics all-media.
In June 2020, the "Outline of Space Planning of Guangming Science City" was approved. Guangming Science City will become a core functional carrier area of the Guangdong-Hong Kong-Macao Greater Bay Area International Science and Technology Innovation Center and an important part of the comprehensive national science center, representing the country to participate in global science and technology competition and cooperation. To this end, Guangming Science City has built a spatial layout of scientific installation clusters with "one main and two deputy" and planned a large scientific installation cluster with an area of 6 square kilometers, as well as a science and education integration cluster and a science and technology innovation cluster. The spillover effect of
large scientific installations is gradually reflected, achieving a breakthrough in the construction of "0-1 (basic scientific research)".
Guangming Science City has concentrated on the construction of 23 major innovation carriers, including 9 major scientific and technological infrastructure, 10 cutting-edge cross-research platforms, 2 Guangdong Provincial Laboratories, and 2 research universities. Among them, the civil construction of the two science city launch areas, the two science city research, brain analysis and brain simulation, will be basically completed and will be put into use next year. Sun Yat-sen University Shenzhen Campus , Shenzhen University of Technology (prepared for) and other universities have officially recruited and run schools in 2021; major innovation platforms such as Supercomputing Center Phase II, Pengcheng Cloud Brain III, Shenzhen Bay Laboratory, Artificial Intelligence and Digital Economy Guangdong Laboratory (Shenzhen) are also being promoted at full speed. Among them, Shenzhen Bay Laboratory, as a benchmark for the integration of science and education, has currently entered more than 90 scientific research teams, with a total of more than 1,000 people.
"The construction of two facilities for synthetic biology research, brain analysis and brain simulation is basically completed and can be officially put into use next year. These two facilities will greatly accelerate the efficiency and process of scientific research through artificial intelligence and digital technology (such as robotic arm ), and at the same time reduce the pain of scientific researchers' repeated experiments." Zhang Dongdong, deputy director of the Guangming District Development and Reform Bureau, said in an exclusive interview with a reporter from Southern Finance and Economics. More than 0 major scientific devices in
html are used as "reliance", and many scientific research and innovation talents are used as motivation. Guangming Science City has selected information, new materials and life as its three main directions, and quickly opened up the situation.After several years of precipitation, the synthetic biological industry chain in Guangming District is now accelerating the filling and optimization of the industry, and the industrial agglomeration effect has begun to appear.When the Shenzhen Science and Technology Innovation Commission surveyed the industries in various districts, it was found that the synthetic biological industry in Guangming District is gradually developing into the first echelon of synthetic biological in the city and even the country.
Guangming District Party Secretary Cai Ying summarized this logic as taking the open sharing of large scientific installations as the driving force, supporting leading enterprises to work with scientific research institutions and other institutions to carry out concentrated research, and at the same time accelerate the formation of a cluster development trend of science and technology innovation enterprises. Through the construction of the large scientific installation industry belt, we will promote the "innovation upstairs, entrepreneurship downstairs" model.
Guangming Science City Launch Area Project. Data picture
The government dares to be The first person to eat crabs
From almost no one cares about it to today being considered a "future industry", the academic and industry have given high praise to the synthetic organisms in Guangming District.
"This is thanks to the support and support of Shenzhen, especially Guangming District for the synthetic biology innovation chain industrial chain . There is no city in the country that can have such good policies. It can be said to be unique." Zhang Youming, an academician of the German National Academy of Engineering and a researcher at the Shenzhen Advanced Technology Research Institute of Chinese Academy of Sciences, said at the China Synthetic Biology Academic Annual Meeting that half of all synthetic biology industries in the country should be concentrated in Guangming Science City.
Southern Finance All-Media reporter learned that the synthetic biology industry, which is in the future industry, will be located in Shenzhen for every two synthetic biology companies established in China, and there is an 80% chance of settling in Guangming Science City. At present, Guangming District has gathered more than 40 synthetic biological enterprises, and the overall valuation of related enterprises exceeds 16 billion yuan. Such achievements as
are derived from Guangming's pioneering and enterprising spirit of promoting enterprises to complete the "1-10".
clock is dialed back to 2018. At that time, the synthetic biological industry had just emerged, and the market had not yet given bioeconomy a broader imagination space, and there were no cases to refer to nationwide, but Guangming District resolutely chose to focus on cultivating the aggregation of synthetic biological industries.
, the Guangming District Science and Technology Innovation Bureau, who participated in the formulation of relevant policies, recalled to Xiaosi to reporters that during the formulation process, leaders of various departments in the district went to industrial parks across the country for inspection. "Guangming's policies should not only be the best in the city, but also compare with the country to achieve the highest and best in the country."
In 2021, Guangming District released the first "1+2" policy system for the synthetic biological industry in the country (i.e., 1 special policy for the development of synthetic biological industry and 2 synthetic biological enterprises and professional park recognition standards). In addition to comprehensive policies, there are many "firsts" for the synthetic biological industry around the "four chains" Guangming District. In terms of basic research in the industrial chain, the investment of 720 million yuan to build the world's first major scientific and technological infrastructure for synthetic biology research (hereinafter referred to as "big facilities") is located in Guangming Science City, filling the domestic technology gap in the integration of synthetic biology facilities software and hardware.
For the innovation chain, Guangming District has established a full-chain enterprise cultivation model of "scientific research-transformation-industry", creating the country's first synthetic biological industry innovation center (hereinafter referred to as "innovation center") as an innovation carrier for the transformation of scientific research results, and supporting the first "upstairs and downstairs" innovation and entrepreneurship complex model. This model allows scientific researchers in "white coats" to work in the same building and entrepreneurs in "suits", greatly shortening the time period from original innovation to industrial transformation.
In the education chain and talent chain that provide scientific research source motivation, the first synthetic biology innovation institute in the country has been implemented brightly. Currently, the team size is 1,000, the number of people in the world is the largest. Full-time academic leader covers Harvard , Yale , MIT and other institutions, and has 50 cutting-edge multidisciplinary cross-research research teams.
"When we first moved to Guangming, there were only more than 20 people. After more than a year of development, Saiqiao Bio's team has now exceeded 100 people. After coming to Guangming, raised nearly 300 million yuan in , and the R&D production area has also expanded to nearly 10,000 square meters of GMP production line and R&D laboratory." Saiqiao Bio's CEO Shang Yuanfang told the reporter of Southern Finance and Economics' all-media that the most important thing in choosing Guangming is the government's determination to build agglomeration of synthetic biological industries.
Saiqiao Bio is the first synthetic biological enterprise introduced in the Guangming District Synthetic Biological Industry Park, and it is also one of the few tool-type companies in the field of cell and gene therapy (CGT) in Shenzhen. Under its demonstration, upstream and downstream enterprises of synthetic biology have been continuously gathering in Guangming, and Guangming District has become the largest gathering area in the domestic synthetic biology industry.
Synthetic Bio-Looking at the Light has become a "common cognition" in its industry.
Guangming also summarized and summarized the development model of the integration of the four chains of "industrial chain, innovation chain, talent chain, and education chain" from the development experience of synthetic biology and the full-chain enterprise cultivation model of "scientific research-transformation-industry". Now, these experiences will be replicated to other key industries in the region.
According to reports, Guangming District will also introduce the "8+5" industrial development support policy in the near future, focusing on providing greater special support from five aspects: the settlement of high-quality enterprises in the entire industrial chain, the transformation of major scientific and technological innovation research and development, the construction of professional public service platforms, the cultivation and development of innovative enterprises, and the creation of an ecological environment for the science and technology industry.
Government departments have planned and expected this. Zhang Dongdong said that according to speculation, the biomedicine or synthetic biology track will break out first and it is expected that results will be produced within 5 years. The breakthrough in the information science and technology industry (such as the integrated circuit field) that everyone is looking forward to may take more than 5 years. Because chips are further breakthroughs, it is necessary to make breakthroughs in the new generation of processes and materials to create the next generation of chips. In addition, there may also be breakthroughs in new materials industry , especially in some special materials.
In 2021, the GDP of Guangming District was 128.533 billion yuan, and increased by 12.9% year-on-year. The growth rate exceeded double digits for the first time since 2015, ranking first in the city. Among them, strategic emerging industries occupy half of the territory of GDP in Guangming District.
Scientific "building a city" gathers innovation elements
Breakthroughs in the industrial chain and innovation chain require support from talents, technology and financial elements. When the Political Bureau of the Central Committee emphasized economic work at the end of last year, it required that science and technology policies be implemented at a faster pace, and key core technologies will continue to focus on key scientific and technological development, strengthen the national strategic scientific and technological strength, strengthen the leading position of enterprises in innovation, and achieve a virtuous cycle of science and technology, industry and finance.
Director-General of the Global Innovation Center and Vice Chairman of the China Social and Economic Analysis Research Association Zhao Gang said in an exclusive interview with a reporter from Southern Finance and Economics All-Media that the evolution from building a "industrial park" to building a "science city", requires the government not only to provide financial support, but also to make achievements in the business environment, scientific research environment, and living environment. Otherwise, the science city will become " sleeping city ".
In order to stimulate the vitality of the industrial environment in the district with a more livable environment, Guangming Science City generally presents a spatial layout of "one heart and two districts, green rings lingering" to create the urban style of "Northern Forest, Central City, and South Valley". Among them, Guangming Central District relies on the planning and construction of Shenzhen Science and Technology Museum and Science Park, focusing on creating a number of three-dimensional urban projects to create a central urban area that is livable, business-friendly and pleasant, and a demonstration model area for industrial and urban integration.
Southern Finance and Economics All-Media reporters learned that Guangming will implement the chief designer system in the planning and construction of large scientific installation clusters, promote the establishment of the Guangming Science City chief designer system work leading by district leaders, and form a technical team of more than 20 people led by the chief planner and chief designer " dual-teacher ", to coordinate and guide the overall design work of cluster planning, construction, transportation, landscape, municipal affairs, etc., and provide technical guidance on the entire process of key projects in the area from planning and planning to construction implementation, and create a high appearance to create an architectural style with scientific characteristics and bright characteristics and a unified style.
Guangming District is building a "Scientist Valley", planning and building scientific research supporting projects such as the Science Mansion, Science and Tourism Home and Multi-functional Hall based on the situation, and creating a new international talent service center integrating open exchange, creative training, and popular science literature and art.
In terms of cooperation between Shenzhen and Hong Kong, Vice President of Shenzhen Advanced Technology Research Institute of Chinese Academy of Sciences and Dean of Shenzhen Institute of Synthetic Biology Innovation Liu Chenli recently proposed to establish the "Hong Kong-Guangming Science City Direct Train", relying on the advantages of Guangming Science City's major scientific and technological infrastructure, establish a special project for the use of major scientific and technological infrastructure, attract top talents from Hong Kong and internationally to Guangming Science City to carry out scientific and technological cooperation, explore the on-site transformation of international cutting-edge achievements, and build a community of coordinated development of the Shenzhen-Hong Kong biological industry.
What is more noteworthy is that Guangming District strives to support scientific and technological innovation and industrial development through finance to achieve a virtuous cycle of science and technology, industry and finance.
htmlIn September, the Guangming District Government and the Shenzhen Branch of the China Development Bank signed a special cooperation agreement on science and technology finance of Guangming Science City with 10 billion yuan. This includes the 1 billion yuan transfer loan agreement for technology-based small and micro enterprises, and the transfer loan of technology-based small and micro enterprises, providing science and technology-based small and micro enterprises in Guangming District. Therefore, in combination with the advantages of "development finance + Internet technology", we will focus on the entire life cycle of scientific and technological achievements transformation, and solve the financing needs of technology-based enterprises in the start-up, growth and maturity stages in a targeted manner. It is estimated that the 10 billion yuan special loan is expected to support 500 technology-based small and medium-sized enterprises and 15 large-scale technology enterprises, and leverage commercial finance by 20 billion yuan.Southern Finance All-Media reporter learned that Guangming District has prepared the first synthetic biology special industry angel fund in the country, and will plan to build the city's first synthetic biology industry fund .
In Shenzhen's "20+8" industrial layout, in order to accurately and efficiently develop industries, Guangming District will gradually realize "one cluster, one fund, one exhibition, one forum, one association, one alliance, and one team" for eight strategic emerging industries such as ultra-high-definition video display, biomedicine, new materials, intelligent sensor, , as well as five future industries such as synthetic biology, brain science, and brain-like intelligence, blockchain, and quantum information. It will gradually realize "one cluster, one fund, one exhibition, one forum, one association, one alliance, and one team", and will implement specialists' responsibility and combat with charts.
Therefore, along the Maozhou River water system, Navy Mountain, Guangming Lake, Dadingling Forest Park, etc., "one river and nine hydration combine two bright lights, and a hundred miles of green mountains enter the prosperous city", the bright ecological background, open space, humanistic nodes and other advantageous resources "beaded into a chain", becoming a shining pearl on the Guangzhou-Shenzhen Science and Technology Innovation Corridor, radiating to the Guangguan-Hui Science and Technology Innovation Activity Circle. In this process, a new path to the science center - the "bright path of scientific research system reform" is being formed.
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