No. 1553 Brain Science Daily
November 10, 2022
Science Times
, PNAS: Only half of the brain is left, and the accuracy of human literacy and face reading can reach 80%
Source: qubit
In addition, even if one eye is covered, the accuracy of normal people in determining faces is still higher than that of patients; however, in terms of word analysis, there is not much difference between normal people and patients who look at the right eye. Normal people who look at the left eye perform better in word analysis than people who look at the right eye. The research team pointed out that the brain is surprisingly malleable, and it can adapt to huge trauma by reconnecting. Losing half of the brain does not mean losing half of its function.
Source: Dalian Institute of Chemicals
Medical diseases are directly related to neurodegenerative diseases, but nerve cells do not exist in isolation. Research in recent years has shown that there is a close interaction between nervous system and the immune system, and immune cells in the brain play a key role in shaping and regulating the nerve function of nerve cells.
Recently, the research team of Lu Yao, a researcher of the single cell analysis research group of the Dalian Institute of Chemical Pharmaceuticals, used the detection technology of a single cell multiple secretion factor to achieve the analysis of the neural-immune cell interaction network. Studies have found that infiltrating macrophages and resident macrophages (microglia) have different effects on the regulation of the secretion function of nerve cells. In addition, the researchers found that the interaction between nerve cells in Alzheimer's disease model and macrophages or microglia can lead to increased secretion of proinflammatory cytokines. This study provides new technical support for a deep understanding of the brain microenvironment and is expected to provide data reference for the discovery of markers of the occurrence and development of neurodegenerative diseases.
3, Science Advanced: HUSH gene silencing complex contributes to normal brain development and function
Source: iNature Life
Histone methylation plays a crucial role in the formation of heterochromatin. Histone methylation is also functionally related to memory formation, neuroplasticity and cognitive ability, while abnormal histone methylation is related to neurodevelopment, neurodegenerative diseases and behavioral disorders. Recently, a research team from , and other research teams from , Austrian Academy of Sciences, conducted some genome-wide screening in human cell lines and identified the HUSH (Human Silence Hub) complex. The complex contains M-phase phosphoprotein 8 (MPP8) and recruits histone methyltransferase SETDB1 and Microrchidia CW-type zinc finger protein 2 (MORC2).
study reported that mouse MPP8 and MORC2A are highly expressed in the brain. The genetic inactivation of Mphosphosph8 or Morc2a in the mouse nervous system will lead to changes in brain structure, impaired motor function and shortened lifespan. In addition, in human brain organs, the number of clustered protocadherin isomers expressed by individual MPHOSPH8 or MORC2-deficient neurons increased. The data reveal new roles of the HUSH complex in regulating clustered protonin within the nervous system, thereby controlling brain development and neuronal fidelity in mice and humans.
4, British Journal of Psychology: Spatial Situation Regulation Gender Perception
Source: Institute of Psychology, Chinese Academy of Sciences
People's perceptual processing of visual stimuli is highly dependent on their situation.A large number of studies have used low-level visual feature processing to reveal that simultaneous contrast and adaptive effects have similarities in behavioral performance and cognitive mechanisms. Recently, researchers from Jiang Yi's research group of the State Key Laboratory of Brain and Cognitive Science adopted a simultaneous comparison paradigm and explored through four experiments whether and how gender perception of faces and biological motion is regulated by the simultaneous presentation of gender information.
study found that humans have a high dependence on their situation on their gender perception of faces or biological movements. The perceptual faces or biological movements are "exclusion" by the gender information near the surrounding situations. Simultaneous comparison of gender and adaptation effects may depend on the same inhibitory mechanism, while and effects show category specificity and consciousness dependence. This suggests that the situational effects of high and low-level visual characteristics may have different biological basis.
5, Adolescents staying up late are more likely to develop antisocial behaviors and will also delay brain development
Source: Quadrupole
Recently, researchers from the University of Melbourne psychiatry published a study on Journal of Child Psychology and Psychiatry, tracking more than 200 teenagers for 7 years. They found that children who often stay up late in early adolescence are more likely to have behavioral problems after a few years, including more aggressive, more prone to violations of rules and antisocial behaviors.
experiment also recorded for the first time how sleep preferences affect the growth of white matter in adolescent brains: white matter in children who often stay up late does not increase as in children who go to bed early and get up early. The brain development speed will also lag behind that of children who go to bed early and get up early.
6, They understand delay satisfying , and have amazing self-control
Source: Principle
Self-control is a kind of ability to resist temptation and strive for better but delayed rewards. The higher your intelligence, the stronger your self-control. jay is a animal widely distributed in Eurasian . It is often nicknamed "feathered ape ". Their cognitive abilities are comparable to those of non-human primates.
A study published recently in Journal of the Royal Society Philosophy B conducted a "marshmallow experiment" on jays. The experiment found that those jays with the strongest self-control also scored the highest in the intelligence test . Each jay performs differently. Interestingly, if a jay is good at one of these tasks, it is good at all tasks, which suggests that their performance is determined by general intellectual factors.
7, never expected! This is the reason that affects women's promotion and salary increase!
Source: Bio Valley
A recent study published in Sex Roles found that for women, better sleep quality will increase positive emotions, and positive emotions will lead to higher career ambitions, i.e., the desire for promotion is increased, but this does not apply to men. Women’s intentions to pursue higher career aspirations seem to be vulnerable to the quality of sleep because at these times, their emotions are less positive. In other words, the better women sleep, the higher their workplace requirements will be put forward, and the more they look forward to promotion and salary increase!
8, Following Eisai, Eisi also saw Alzheimer's disease Dawn
Source: New Drug Frontier
Recently, Eisi//Bijian jointly announced that the Phase 3 Clarity AD clinical study of the anti-beta amyloid (Aβ) antibody lecanemab, used to treat mild cognitive impairment (MCI) caused by Alzheimer's disease, achieved positive and critical results, that is, the Clarity AD trial reached the primary endpoint and all key secondary endpoints, and the results were highly statistically significant.
Eli Lilly said the lecanemab study found that early-stage Alzheimer's disease patients who were treated had a 27% decline in clinical performance, providing additional validation for the beta amyloid hypothesis, which promoted the development of Eli Lilly's own donanemab.Eli Lilly also introduced the progress of its next generation amyloid plaque-targeting monoclonal antibody remternetug, which has entered the Phase 3 trial, with the main endpoint being amyloid plaque removal. But like donanemab, the program will eventually expand to assessing clinical impacts.
Review: Simon
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