Some racists always advocate how pure their ethnic ancestry is, in order to devalue and discriminate against other ethnic groups. Little do we know that hybridization has better advantages in species evolution. Human beings have become smarter throughout the entire evolutionary process through continuous hybridization.
gene research has proved that all modern people are descendants of African Homo sapiens. These Homo sapiens began to migrate to all parts of the world about 100,000 years ago. The previous Homo sapiens was also the result of hybridization of various races after they evolved from to to . In the process of migrating to all parts of the world, Homo sapiens' ancestors still maintained the tradition of lust and crossed with other races all the way, which led to the emergence of increasingly smart modern humans.
In this sense, lust is not a derogatory term, but the driving force for the development of almost all animals. Earlier, science has proved that the Neanderthal (hereinafter referred to as Neanderthal ) gene exists in modern human genes, and Swedish scientist Svante Pääbo (Svante Pääbo) found that in modern human genes, there is also a newly discovered extinct species~ the gene of the Denisovan.
This achievement is of great significance to humans to understand themselves, as well as the future medicine, health and longevity of human beings. For this reason, Svanter Parbo won the 2022 Nobel Prize in Physiology or Medicine. Now let’s interpret this achievement and its significance.
Let’s first learn about the relationship between Neanderthals and humans
Before the release of Svanter Parbo’s research results, the question of where modern people came from began to become clear due to the great success of gene sequencing projects. Research shows that nearly 8 billion people in the world are founded in Africa. These Homo sapiens began to migrate to all parts of the world around 100,000 years ago.
During the migration process, he encountered another branch of the race ~ Neanderthals, referred to as Neanderthals for short. In order to survive, Homo sapiens, who have the advantage of quantity and intelligence, hunted and drove these Nigers to remote and cold barren lands, and on the other hand, they continued to carry forward the tradition of lust and did many shameful things for sex. The civilized term is "intermarriage".
So, although these Nigerians became extinct 40,000 years ago, their bloodline was left to descendants, and modern human genes generally contain 1 to 4% of Nigerian genes. The distribution of these genes is: Africans basically do not have this gene, while Europeans have the most. Asia is further divided into East Asia and West Asia. There are more people in West Asia and fewer in East Asia. We Chinese have about 1% Nirvana gene.
Therefore, it can be said that the Ni people are also our ancestors. The genes of this ancestor are both good and bad. For example, there is a gene called FOXP2, which is the gene responsible for speaking. This gene improves the language ability of descendants. The concept of language is a tool of thinking, which greatly promotes human self-awareness and logical thinking ability.
In this sense, it is the hybrid advantage of Homo sapiens and Nigerians that makes human offspring become smarter and smarter. The different gene expression rate of in different regions may be related to the number of html people in different regions at that time.
Modern people have also inherited the HLAciass1 gene of the Nigerians, which gives humans stronger antiviral ability and strengthen immunity; and research also believes that the progesterone receptor gene inherited by the Nigerians can improve women's fertility and reduce bleeding and miscarriage rates in early pregnancy.
Dani people also have bad genes. A study published in the journal Nature in September 2020 believes that severe respiratory failure caused by the new coronavirus is highly correlated with a gene cluster on chromosome 3, and this gene cluster contains a fragment of about 50kb left by the Nigerians. One of the authors of this research paper is Svanter Parbo.
This gene fragment is the most common among South Asians, up to 30%; Europeans are second, reaching 8%; Americans are also 4%. But East Asia and Africa do not. This can lead to a inference that the proportion of severe illness in West Asia will be larger, especially in India; China belongs to East Asia, so it is much better. It has been two years since this paper was published. Is this inference accurate? Let’s analyze and judge for yourself.
Neurogenic genes may also cause modern humans to be more susceptible to Parkinson's disease (Alzheimer's disease), depression, type 2 diabetes, smoking and alcohol addiction, etc. Modern people are sensitive to pain; some people have prominent heads and are ugly, which is also related to the Nigerian genes.
Therefore, there are advantages and disadvantages in natural hybridization, and overall, the advantages outweigh the disadvantages. Yuan Longping's hybrid rice takes advantage of this advantage. In modern gene breeding, it is to use the most modern technology to add or retain the most favorable fragments of the gene, cut off and discard those disadvantaged genes, and allow the species' advantages to be maximized.
Interpretation of Denisovan research results
0 The Nobel Prize Committee evaluated Svanter Parbo as: by revealing the genetic differences between today's humans and the extinct ancient humans, he laid the foundation for exploring what makes us unique humans, and thus pioneered a new scientific discipline ~ paleogenomics.
This means that it is precisely because of the hybridization between ancient human populations that the uniqueness and civilization of modern humans are found.
Swant's research on the Denisovans began in 2008. This year, scientists found a phalanx fragment from 40,000 years ago in the Denisova Cave in the south of Siberia. Research has found that this phalanx belongs to a young girl, and scientists call this girl "X Girl".
It is gratifying that this phalanx fragment actually contains a very good genome, and a full 10 mg of high-quality DNA was extracted. Svanter led his team to complete the sequencing of the phalanx gene in 2014 and found that "Girl X" is a new race that has never been discovered before, named "Denisovan" (hereinafter referred to as " Dan ").
This discovery caused a sensation in the world and was rated as one of the top ten scientific breakthroughs of the year by the Science magazine on December 21, 2012. Research has found that although the Danes are of the same origin as Homo sapiens and Nigers, they were separated by 1 million years ago. They belonged to the same ancestor, the ancient Heidelberg people, and their matriarchy may be pioneers.
These Dan people appeared in Northeast Asia 300,000 years ago, and many of their remains were left in the land of China. After 80,000 years of survival struggle, they eliminated the "indigenous" Homo erectus (the Peking Man population unearthed from Zhoukoudian) and became the new "indigenous" here.
The Jinniu Mountain culture 280,000 years ago, the Dali culture 200,000 years ago, the Maba culture 130,000 years ago, and the Xujiayao culture 100,000 years ago, all of which have been discovered in my country have the remains of these activities of the Dan people. These relics were originally considered to be the early Homo sapiens culture in , and should now be corrected as Danish culture.
But the splendid Danish culture disappeared 20,000 to 30,000 years ago, and the last trace was in the Siberian plain. Research believes that the reason for the disappearance of Danes is likely to be the same as that of the Nigerians, which was caused by the African Homo sapiens migration. These "indigenous" Dans who had survived here for hundreds of thousands of years declined in competition with smarter and more Homo sapiens. The withered remnants were driven to the bitter and cold Siberia and eventually perished.
Some studies believe that in the cruel racial struggle, the Nepali became food for Homo sapiens, and perhaps the fate of the Dans is the same.
But hunting each other does not prevent these human ancestors from continuing to be lustful. They still go on a slutty manner in different regions and environments. Whether it is the way of being captured as a sexual slave or the tenderness and sweetness of love, many mixed-race descendants of humans have been left behind. Genes cannot be deceived, and among some today's human populations, Danes' gene expression is even higher than that of Nigers.
This relationship first appeared in people in Melanesia and Southeast Asia and other regions. The individual carries up to 5~6% of the Danish genes, and also reaches 4% in Australian indigenous . Through the genetic analysis of Tibetans in China, there is a fragment that cannot be found in other humans. After sequencing and comparison, it was confirmed that the gene originated from the Denisovans. Further research found that 94% of Tibetan genes come from modern races and 6% come from extinct Dan people.
At the same time, through the analysis of the respective EPAS1 genes of Tibetan and Chinese ethnic groups, the two ethnic groups had common ancestors 5,500 years ago, and the separation occurred 2,750 to 5,500 years ago. The Dan people were genocide 20,000 to 30,000 years ago, so it can be inferred that the blood ties of the Han people in should be like Tibetans, with the Dan people's genes.
However, I did not find the research conclusion in this regard, but I was just a logical speculation for reference only. The Danish genes have certainly had an impact on human offspring. What are the advantages and disadvantages of these effects? Space-time communication has not found any reports on this. I believe scientists are still conducting in-depth research and will soon reveal more new discoveries.
The great significance of Svanter Parbo’s discoveries and research results:
Svanter Parbo’s research reveals a new existence of ancient humans and their relationship with modern humans. And through his research processes and methods, including extracting, sequencing, drawing genome sketches of ancient humans from fossils, analyzing the genetic differences between all modern humans and extinct humans, providing a foundation for exploring how modern humans become unique humans.
Thus, a brand new scientific discipline is established ~ paleogenomics. This discipline will open up a new world for future research on ancient humans and human evolutionary history, and even the research on the evolution of paleontology . It can be foreseen that such a new discipline will be added to future university textbooks.
Through the interpretation of the Nobel Prize awards by many scientists such as Svanter Parbo, we can better understand the charm and contribution of the Nobel Prize in Science. The achievements commended by these awards are all pioneering scientific events and play a crucial leading role in the advancement of human civilization.
What do you think about this? Welcome to discuss and comment.
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