In recent years, the field of coronary intracavitary imaging and physiology has flourished, especially the non-invasive coronary physiology evaluation method has been updated and iterated continuously. Recently, Jiangxi Cardiovascular Hospital, led by the director of Hong Lang, took the lead in introducing a new generation of quantitative blood flow fraction (QFR) to guide coronary interventional surgery, becoming the first hospital in the province to update this technology.
The new generation of AI QFR measurement system has a simpler interface, smarter operation and more accurate calculations
As we all know, the blood flow reserve (FFR) is the gold standard for evaluating whether coronary artery stenosis has functional significance . All major guidelines list FFR-guided interventional therapy as a category I recommendation, but the clinical application of FFR is not ideal. The main reason is that FFR measurement requires the use of a disposable pressure guide wire, which is expensive, and the measurement process requires the use of adenosine, which increases the number of patients Discomfort, and the entire operation process is relatively complicated. Based on these problems, the team of Professor Tu Shengxian from Shanghai Jiaotong University independently developed the QFR measurement system, which became the only imaging FFR technology in the world that has obtained European CE certification, US FDA certification, and China NMPA (CFDA) certification. Prelude to accurate assessment of pulse non-invasive function.
The first generation of QFR measurement results interface
Jiangxi Cardiovascular Hospital carries out nearly 4000 coronary interventional operations every year, which is the hospital with the largest amount of such operations in the province. Dean Hong Lang introduced QFR technology to Jiangxi for the first time in June 2020 and put it into use in coronary intervention surgery, benefiting the majority of patients with coronary heart disease. This time, Hong Lang closely followed the academic frontier and introduced the new-generation QFR system to Jiangxi shortly after it was developed, marking the official entry of QFR clinical application in Jiangxi Province Cardiovascular Hospital into the 2.0 era.
According to Dr. Zhu Hongmin from the Department of Cardiology, QFR is a guidewireless FFR rapid analysis system based on coronary angiography images. The first-generation QFR measurement is based on two conventional coronary angiography images with an angle difference greater than 25°. Reconstruction and blood flow analysis,In order to obtain the blood flow reserve score. The new generation of AI QFR technology has greatly improved compared with the previous generation technology. Firstly, artificial intelligence algorithms are added on the basis of the first-generation QFR homologous core algorithm, such as the calculation of blood flow velocity and the selection of blood vessel segments of interest. Lumen contour drawing, branch calculation, etc. are integrated with artificial intelligence algorithms, which greatly simplifies the personal operation process and reduces the personal operation error, so that the calculation is more accurate and the time is shorter; secondly, the new generation of AI QFR can complete 2D separately -QFR and 3D-QFR measurement. For lesions that are clearly exposed by coronary angiography, only one contrast image is needed, and 2D-QFR analysis can be completed within 30 seconds, with a calculation accuracy of over 93%; 3D-QFR can be performed for complex lesions Analysis needs to be combined with two-dimensional angiography images, and the analysis can be completed in about 1 minute. Thanks to the assistance of artificial intelligence, it is more accurate than the previous generation of QFR calculation; third, artificial intelligence based on angiography assists automatic coronary tree non-invasive FFR calculation , Is currently the world's exclusive technology for functional analysis of bifurcation lesions; finally, in the AI QFR system, the calculation of microcirculation function has been added, thereby improving the physiological function assessment of the whole coronary system. Based on these advantages, it is believed that QFR will have broader application prospects in the future.
(Jiangxi Cardiovascular Hospital Zhu Hongmin)
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