Zhejiang University scientific research team cracked the "energy code" of spinach. The results were listed in the
cartoon of " Nature " magazine. "Popeye" can pull cliffs and catch lightning after eating spinach. In reality, scientists have also made new achievements in cracking the "energy code" of this green vegetable.
In the early morning of December 8, Beijing time, the major achievements of the research team of Run Run Shaw Hospital affiliated to Zhejiang University School of Medicine were listed in the form of a long article (Article). Dr. Lin Xianfeng, Professor Fan Shunwu's team of orthopedics, Shaw Hospital Affiliated to Zhejiang University School of Medicine, and Professor Tang Ruikang's team successfully extracted "biocells" from spinach, and for the first time in the world, it has achieved the delivery of plant thylakoids into the cells of aging lesions in animal bodies, allowing animal cells to have the energy of plant photosynthesis.
Screenshot of the Nature magazine website page.
At the same time, the "Research Briefing" column of "Nature" published "Plant Cell Devices Realize Metabolites Transfer to Mammalian Cells", actively evaluating the research results.
According to reports, the main breakthrough point of this study is to develop the cell membrane nanocoating technology, which covers the mammalian cell membrane on the outer layer of nano-sized plant thylakoids. Through the cell membrane camouflage encapsulation, plant thylakoids are transplanted across species to mammalian cell , successfully unlocking the energy transmission code across species, and knocking on the "gate of time" to reverse cell degeneration and aging.
How much role can the "black technology" of nano thylakoids play in the human body? In order to test whether this "biocell" can reverse the metabolic status of lesion cells, Fan Shunwu led the team to first select the disease model of osteoarthritis for "conceptual verification". Osteoarthritis is one of the main causes of teratogenic disability in clinical practice. Due to the imbalance of energy metabolism of chondrocytes, the destruction of articular cartilage in the current biological treatment of osteoarthritis cannot systematically correct the metabolic imbalance of damaged degenerate chondrocytes, so the clinical prognosis is poor.
Lin Xianfeng (left) and team members, Chen Pengfei (right) of the orthopedic department of Run Run Shaw Hospital affiliated to Zhejiang University School of Medicine were in experimental exchanges. (Photo provided by the interviewee)
research team constantly seeks various interdisciplinary technical means. After more than 4 years, nanothyloides encapsulated by the chondrocyte membrane can not only effectively avoid the removal of the immune system, but can also be selectively ingested by degenerated chondrocytes. Through non-invasive light in vitro, reshape the anabolic of chondrocytes, thereby realizing the treatment of degenerative osteoarthritis disease.
It is understood that most of the members of the research team are "post-90s". Lin Xianfeng, born in 1990, told reporters that he encountered many difficulties in the scientific research process. Today's results are thanks to the guidance and encouragement of his predecessors, and we also need to thank the team members for their support and encouragement. "The first author and I are both clinicians. Our original intention is to bring hope to patients and have more choices when treating them," he said.
reporter learned that the research team has submitted the invention patent simultaneously and started product conversion. It takes about 3-5 years to apply the results to clinical practice. This scientific research result may be used in the treatment of other diseases in the future, including intervertebral disc herniation, cardiovascular cell aging, muscle atrophy, etc., which is of great significance to the repair of important organs in the human body. In addition, this achievement is expected to have new applications in biofuels, energy and chemical industries.
Source: Xinhua News Agency
Reporter: Guo Yuqi, Huang Xiao
Source: Xinhua News Agency
