At the beginning of the article, Xiao Hu wants to ask everyone a question. When you wake up, have you ever seen a blue or purple one on your body, and it has appeared inexplicably. Then the elders at home would say that this is a "ghost pinch". Are you convinced? When I grew up, I realized that it was purpura . Purpura is caused by the rupture of skin capillaries for some reason, but most of them appear on the skin. Have you ever seen one that grows to the liver?
Ms. Gao is 44 years old this year. She went to the hospital with abdominal pain last year. The imaging examination revealed that there were multiple space-occupying lesions in the liver . Ms. Gao was terrified and ran to several hospitals for examinations. Eventually, there were multiple nodules in the liver and the nature was difficult to determine. It was suspected to be benign or low-grade malignant tumors. In September last year, Ms. Gao underwent surgery to remove the diseased part of the liver. But what is unexpected is that no tumor cells were found in the pathological samples cut!
In November, Ms. Gao came to Shenzhen Third People’s Hospital . The doctor said, “The CT examination results are very similar to liver cancer, but the pathological results and some symptoms are not It does not meet the characteristics of liver cancer, this must not be a common disease." Afterwards, multiple doctors discussed together, ruled out the tumor, and diagnosed hepatic purpura! The doctors in the same department have not seen such cases in 40 years of medical experience! It is understood that Ms. Gao is the first patient with hepatic purpura in Shenzhen. After the diagnosis, after symptomatic treatment, Ms. Gao's condition has eased and she has been discharged from the hospital.
What is hepatic purpura?
Hepatic purpura is a relatively rare benign lesion with hepatic vascular lesions.In liver resection or biopsy specimens, multiple blood-filled cysts of varying sizes can be seen in the liver parenchyma. The main reason is that the microscopic manifestation is the expansion of the sinusoidal cavity in the liver, filled with blood, and the macroscopic purple or dark gray is named.
What is the cause of hepatic purpura?
The etiology and pathogenesis of are still unclear, and the clinical manifestations are also complicated. The first report of this kind of lesion was in 1861, and it was named after the liver pathological biopsy description in 1961! According to early studies, the cause of hepatic purpura may be related to drugs, toxicant exposure, tumors, viral infections, and low autoimmunity. Related drugs may include androgen, contraceptives, azathioprine and so on.
With the in-depth research, people have found that it is related to liver and kidney transplantation, steroid hormone use, and HIV infection. Among them, HIV may be a single pathogenic factor, which may be related to AIDS patients with low immunity and opportunistic infection of bacilli, causing bacillary purpura, which was previously called bacillary hemangioma.
is easy to be misdiagnosed!
Hepatic purpura can easily be misdiagnosed as other diseases, such as tumors. This is due to the dilation of the sinusoids in the liver tissues and the accumulation of blood, forming a blood lake. It looks like a space-occupying in the imaging examination, but in fact this is not a real space-occupying lesion. Although it looks very similar to a tumor, the specific diagnosis still depends on the doctor's experience.
Finally, the nurse would like to say that hepatic purpura generally has a good prognosis, but due to the risk of spontaneous rupture and bleeding in the congested cyst, it is still necessary to be aware of the countdown "time bomb" at these moments. .
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