On December 8, 2022, the National Health Commission of released the latest " Home Treatment Guide for People with New Coronavirus Infection " . This guide lists common drugs to cope with different symptoms of COVID-19 , among which Lianhua Qingwen Capsules , aspirin, and ibuprofen are ranked first. is very familiar to Lianhua Qingwen Capsules and Aspirin. These are two common cold and fever drugs, and they also have a certain effect on preventing and treating the new crown.
However, when it comes to ibuprofen, many people are puzzled: "Ibuprofen is not a painkiller? Can it also treat the new coronavirus?" So what is ibuprofen and what is its function? In response to this problem, I will introduce to you in detail what kind of drug ibuprofen is and how we can use it correctly.
Can ibuprofen treat COVID-19? What did it do secretly after entering the human body?
Due to ibuprofen's strong analgesic and anti-inflammatory ability, it is often used as a drug for treating arthritis in clinical practice. Therefore, many people have ignored its antipyretic effect. actually has good efficacy for common colds, fevers and new crowns. So why does ibuprofen have such ability, and what does it do after entering the human body?
It turns out that the "main murderer" that causes fever, inflammation and pain in the human body is prostaglandin . It is an endogenous heat-causing and inflammatory mediator. Excessive prostaglandin in can cause blood vessels to dilate, causing local congestion, edema and pain. Not only that, also causes the infiltration of leukocytes in human and . When white blood cells resist external bacterial and viruses, they will cause an increase in the body's body's body temperature, resulting in symptoms of fever.
ibuprofen will stimulate the hypothalamus after being absorbed by the human body, inhibiting the function of cyclooxidase , thereby inhibiting the synthesis of prostaglandin in the anterior region of the hypothalamus . Because the concentration of prostaglandin in the human body decreases, various inflammations and pains are unsustainable, so ibuprofen has the effects of analgesic, anti-inflammatory and antipyretic effects.
Doctors specifically remind that you should pay attention to the following issues when using ibuprofen
Although ibuprofen has good analgesic, anti-inflammatory and antipyretic abilities, it also has certain effects on the treatment of new crown. However, we cannot take this type of medicine at will. We need to pay attention to the following issues when using it.
First of all, other similar Chinese and Western medicines are prohibited during the medication period. The same antipyretic drugs such as Lianhua Qingwen , Jinhua Qinggan, Gankang, Baijiahei , etc. If taken with ibuprofen, it will have a strong stimulating effect on our liver organs. In this case, will not only fail to relieve the symptoms, but will also lead to the occurrence of toxic side effects such as acute liver failure.
Therefore, when we choose this type of drug, we remember not to be greedy and use multiple detoxification drugs at the same time to avoid unnecessary harm.
Secondly, each time must be 4-6 hours apart when using ibuprofen to reduce fever. Everyone knows that after entering the human body, the drug usually reaches the highest peak of blood concentration in about 2 hours, and then slowly is metabolized out of the body. sets the interval between ibuprofen at 4-6 hours. On the one hand, it can give the drug enough time to produce therapeutic effects, but on the other hand, it will not cause excessive stimulation to the human body and lead to side effects.
Of course, when using it, you also need to follow the doctor's guidance , because everyone's physical condition and disease condition are different, the dosage of medicines that need to be used will also change to a certain extent. Therefore, for different people, the dosage and interval time of each time will be different.
Finally, you cannot smoke or drink alcohol during the period of taking ibuprofen. As a nonsteroidal anti-inflammatory drug, ibuprofen has certain gastrointestinal toxicity. According to the above, we have already known that ibuprofen will inhibit the synthesis of prostaglandins, and prostaglandins have the function of protecting the gastric mucosa in the human body. Therefore, taking ibuprofen will cause certain damage to the stomach and intestines.
If we do not control ourselves at this time and smoke and drink at will, it is likely to cause secondary damage to the stomach and intestines, resulting in chronic gastritis and even gastric bleeding. Therefore, when taking ibuprofen drugs, you must restrain yourself and not smoke or drink alcohol.
3 people use ibuprofen with caution, and taking wrong is harmful
According to statistics from the National Food and Drug Administration , There are more than 2.5 million people in my country who cause physical health damage due to wrong medication every year, of which nearly 200,000 people have left the world because of this, Therefore, we must be cautious and cautious about the use of drugs.
For ibuprofen, there are many groups that are not suitable for taking it. If you do not choose according to your actual situation when choosing a drug, but instead go to a pharmacy to buy it blindly, is likely to cause some serious toxic side effects due to the wrong medication, which will eventually lead to irreparable consequences.
Here, I have summarized the following three types of people for you. These groups must use ibuprofen with caution.
first category, people with severe renal insufficiency. The human body's kidney is an organ with extremely rich blood vessels. The smooth flow of the kidney blood determines whether a person's kidney function is strong. has been found that prostaglandin plays a very important role in the expansion of renal blood vessels. . Taking ibuprofen will inhibit the synthesis of this type of prostaglandin, causing poor blood circulation in the kidneys and ultimately damage the kidneys.
People with severe renal insufficiency have serious kidney problems. If the smooth circulation of kidney blood cannot be guaranteed at this time, it is very likely that kidney disease will further worsen, leading to renal failure or even uremia . Therefore, people with severe renal insufficiency must not use ibuprofen when choosing cold and fever-reducing drugs to avoid irritating the kidney system and causing damage.
Class 1 Second category, patients with gastrointestinal diseases. conducted an experiment on the effect of ibuprofen on the gastrointestinal tract. They selected a large number of patients taking ibuprofen and performed gastroscopy examination on them. results found that 23% of patients had gastric mucosa erosion, and 17% of patients had gastric mucosa damage . Especially in the first 30 days of taking, many patients experienced gastric bleeding of varying degrees.
Researchers believe that drugs such as ibuprofen can damage the gastric mucosa and lead to the emergence of gastrointestinal diseases. If patients with gastrointestinal diseases choose to use drugs like ibuprofen, there is a certain probability that the condition will be aggravated. Therefore, friends with bad stomachs should use it with caution to avoid further damage to the stomach.
Class III, pregnant women. Through continuous research on ibuprofen, scientists have discovered that ibuprofen can enter the fetus through the placenta, and can also be found in large quantities in breast milk. Although there is currently no direct evidence that ibuprofen can cause human malformations, can still be proved through experiments on mice that ibuprofen has hindered blastocyst implantation and has a certain negative impact on embryo formation.
Therefore, women during pregnancy and pregnancy preparation should pay attention. For the health of their children, we must not take it lightly. It is an important thing to eliminate all external factors that may affect the healthy growth of children. So it is best for women to use ibuprofen during this period to avoid any unnecessary impact on the health of their children.
Conclusion
As a recommended drug for the new crown, ibuprofen has been favored by more and more people due to its powerful ability to analgesic, anti-inflammatory and antipyretic. "It's the medicine three parts poisonous." , especially as a Western medicine, cannot be ignored. It is better to use it with caution for patients with renal insufficiency and gastrointestinal diseases and pregnant women.
Of course, if there are no special circumstances above, ibuprofen is also a good therapeutic drug.We need to note when using it, ibuprofen cannot take at the same time as other similar drugs. In addition, the dosage and interval time should be specified according to the doctor's order. Not only that, smoking and drinking should be prohibited during the medication period to avoid side effects.
ibuprofen is a double-edged sword. When using it, you need to seek profit and avoid harm. I believe that friends will definitely achieve the ideal effect after using it correctly.
References:
[1], Zhou Shuxin, Wang Weigang, Precautions for prescription non-steroidal anti-inflammatory drugs, World General Practice Work View. March 2010, Vol. 13, No. 3A, 1007 -9572 (2010)03-0741 -04.2010.03.13.
[2], Luo Ting, Liu Huichang, Precautions for the use of non-steroidal anti-inflammatory drugs in the elderly. Journal of Nursing Continuing Study 1990, Vol. 5, No. 11.Affiliated Hospital of Guiyang Medical College .1990.05.11.