When Xiao Wang was playing a popular game, he met a CP. The two of them chatted very well and the content they were interested in was similar. It seemed that there were endless topics to talk about every day.

Xiao Wang (pseudonym) met a CP while playing a popular game. The two of them chatted very well, and the content they were interested in was similar. It seemed that there were endless topics to talk about every day.

Just last week, Xiao Wang had made an appointment with netizens to show up, but after he arrived at his destination, netizens were reluctant to see him and sent a message to netizens, but it turned out that he was blocked.

He felt very depressed for this and his mood was completely out of control. Then he went to the pharmacy to buy cephalosporin medicine, and took cephalosporin while drinking.

Not long after taking the medicine, he developed symptoms of chest tightness, sweating all over his body, nausea and vomiting. Fortunately, passers-by noticed his strangeness and quickly called the ambulance. Xiao Wang was sent to the hospital and was diagnosed with disulfiram reaction . Fortunately, the delivery time was not too late, and the man was rescued and was safe.

Afterwards, the man regretted what he did and was determined not to joke about his life no matter what.

We often hear that "cephalosporin is just wine, and you can leave when you say it". Will eating the two together really endanger life? What is the disulfiram-like reaction?

1. What is a disulfiram-like reaction?

There are often cases of death due to disulfiram-like reactions on the Internet. What exactly is it? The reaction of

after taking medicine is called a disulfiram-like reaction. The more typical drug that causes disulfiram-like reaction is cephalosporin. Cephalosporin drugs mostly contain methiotetraazole side chains, which will inhibit the activity of acetaldehyde dehydrogenase .

If you drink alcohol after taking the medicine, it will cause alcohol ethanol to oxidize to acetaldehyde and cannot continue to decompose. In this way, the acetaldehyde in the body will gradually accumulate, which will cause the drinker to suffer from acetaldehyde poisoning .

specifically manifests as chest tightness, shortness of breath, cyanosis of the lips, difficulty breathing, accelerated heart rate, decreased blood pressure, trance , etc. In severe cases, allergic shock may even occur.

Then why do some people drink alcohol and eat cephalosporin, but they have no reaction?

This is because the amount of alcohol that each person is exposed to and the sensitivity of the individual's body is different. The more alcohol that is exposed to and the more sensitive the body is, the more severe the disulfiram-like reaction will occur in people. In most cases, disulfiram reactions do not cause life-threatening worries.

But for people with relatively sensitive body and poor heart function, this is likely to become a "deadly weapon" . For the sake of your own life, it is better not to drink alcohol after taking medicine.

2. How long will it take to drink after taking cephalosporin?

So, for some people who have eaten cephalosporin, how long does it take to get a drink if they want to drink?

Strictly speaking, it is recommended to stay away from alcohol after taking medicine, and the same applies to any alcohol. For people who have taken cephalosporin, the half-life of the drug is different, and the time required to be separated from alcohol consumption is also different. The safer interval for

is that after taking cephalosporin, you should avoid drinking alcohol and intake of foods and drugs containing alcohol within 1 week. htmlDrinking after 12 weeks is a safer interval for .

How long does it take to take cephalosporin after drinking? This problem mainly depends on whether ethanol and acetaldehyde are still left in the patient's body.

Scholars have conducted surveys on healthy volunteers in my country and found that different groups of people have different metabolic abilities to ethanol, with a peak time of 0.8 to 2 hours and an elimination half-life of 0.5 to 2.6 hours. In other words, needs to go through 3 to 15.6 hours of ethanol in the body to basically remove .

In order to ensure safety, should ban the drug within 24 hours after drinking, and should also avoid using drugs that may react with alcohol within 2 to 3 days. It will be relatively safe after 3 days.

3. In addition to cephalosporins, don’t touch these 5 medicines after drinking

In fact, in addition to cephalosporins, there are many other medicines that cannot be drunk after taking them. Let’s look at the details together.

, sleeping pills

, sleeping pills are actually brain inhibitors. Drinking alcohol after taking the medicine will speed up the body's absorption of drugs and slow down the metabolism of drugs.

This will severely inhibit the normal activity of in the central nervous system , can easily cause shock , coma, respiratory failure , and even death .

, antihypertensive medicine

Drinking alcohol after taking antihypertensive medicine will cause vasodilation, the body's absorption of drugs will accelerate, which will then cause hypotension and , and may also cause symptoms of shock.

If you drink glucose wine, the tyramine contained in it accumulates in the body, which will cause great harm to health, including causing increased blood pressure, arrhythmia , cerebral hemorrhage, etc.

, hypoglycemic drugs

Alcohol will stimulate the secretion of insulin . Drinking alcohol after taking the medicine will cause the patient's blood sugar to drop too much, which is easy to cause blood sugar to occur. and antidiabetic drugs such as metformin, taking them together with alcohol will increase the risk of lactic acidosis , and may cause symptoms such as nausea and weakness.