It's not just that I'm just the latest discovery of
hepatitis E is the last discovered hepatitis virus : In 1978, hepatitis E was first discovered in the Kashmir Valley in India; until 1990, the Tokyo International HNANB and Blood Infectious Disease Conference was officially named Hepatitis E (the fifth viral hepatitis. Although hepatitis E is ranked as the "old fifth" in viral hepatitis, it has existed for a long time, and the harm cannot be ignored. .
Reveal the veil and formally get to know Hepatitis E
HEV belongs to the HEV family, with an icosahedral spherical particle with a diameter of 32nm (27~34nm). Under an immunoelectron microscope, it can be seen that the solid and hollow particles have dense internal density, are complete virus particles and are infectious, and the hollow particles are transparent inside, and are defective virus particles that are incomplete and have no infectivity. The center of the complete HEV particles is HEV ribonucleic acid (HEV RNA), The outer periphery is the capsid.
WHO estimated that about 20 million people are infected with HEV every year, causing about 3.3 million people to have infection symptoms in 2015, the number of deaths caused by hepatitis E reached 44,000.
Confused with the public, difficult to identify
Clinical manifestations are recent occurrences, lasting for more than a few days, but no other reason can be solved The symptoms released are such as fatigue, poor (loss of appetite), nausea, vomiting, upper abdominal discomfort, liver pain, abdominal distension, diarrhea, etc. Some patients may have mild liver enlargement, tenderness and percussion pain, and the urine color gradually deepens. Physical examination shows that the liver enlargement and tenderness, liver percussion pain, scleral yellow staining , etc.
Severe patients can lead to liver failure or even death, 3%-10% of acute hepatitis E patients may have prolonged disease for more than 6 months, i.e. chronic hepatitis E. extrahepatitis E. Neurological , urinary system, blood system and other manifestations. Extrahepatic manifestations caused by hepatitis E are increasingly valued and included in the guideline.
The susceptible population also focuses on the focus, and pregnant women and elderly people focus on
The population is generally susceptible, and infection is mainly transmitted through fecal-oral, blood, mother-to-child and close contact channels. Among them, fecal-oral transmission is the most common transmission pathway, but recent studies have found that the risk of infant transmission and blood transfusion transmission increases.
Hepatitis E infection source: Hepatitis E patients, hidden infections, contaminated water sources, pigs, cattle, sheep, seafood, etc.
After pregnant women are infected with HEV, the condition is more serious, especially in the middle and late pregnancy pregnant women, the mortality rate can be as high as 20%-50%. It is easy to develop into liver failure, and it is also easy to cause premature birth, stillbirth, and major postpartum bleeding , aggravate the condition. The incidence of adverse fetus caused by pregnancy with hepatitis E has significantly increased (miscarriage, premature birth, stillbirth and newborns) 1. Hepatitis E is transmitted vertically through mother-to-child, causing intrauterine infection of the fetus, leading to acute hepatitis E in the newborn, significantly increasing the risk of death in perinatals.
Compared with non-elderly patients, elderly patients with hepatitis E are more likely to experience cholecystitis, electrolyte disorders , spontaneous peritonitis , hepatic encephalopathy , hepatic encephalopathy , hepatic kidney syndrome , and liver failure. In addition, the elderly are infected with H The incidence and mortality rate of severe hepatitis E after EV is relatively high.
Sanitation issues are not ignored, vaccination is the most beneficial
Traditional strategies for prevention and control of hepatitis E through improving water source sanitation conditions may no longer be feasible. Cutting off pig source infection, shortening the infection period, protecting susceptibility and high-risk groups is the key. Vaccination is currently the most economical and effective prevention method. In 2012, the world's first hepatitis E vaccine was born in my country, and China became the first and only country in the world to have hepatitis E vaccine.
In the first year, the protection rate is as high as 100%
4.5 years after vaccination, the protection rate is as high as 93.3%
7.5 years after vaccination, the protection rate is as high as 91.7%
Vaccination produces antibodies, and the continuous protection effect lasts for 30 years
Warm reminder:
Embroidery service stations below Yinchuan can receive hepatitis E vaccine
Digital connection of Dongzhiyue, Xingqing District 1.
. Tel: 0951-3308699
. Address: 50 meters east of Dongfangyue Community (Dongzhiyue Digital Vaccination Center)
. Bei'an Community Health Service Station
. Tel: 0951-5021131
. Address: Building 10, Bei'an Community, Fenghuang North Street, Xingqing District.
. 1. Kyle Mansion Community Health Service Station
. Tel: 0951-4117413
Address: No. 21 Xiuye Road, Xingqing District
Source: Yinchuan News Network
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