Since he was over 60 years old, Mr. Zhang often needs to take statins to control his blood lipids. A few days ago, he just received a call from the hospital after lunch. Mr. Zhang could go to the hospital to test his blood lipids. He thought to himself why the hospital was so tho

Since he was over 60 years old, Mr. Zhang often needs to take statin to control his blood lipids . A few days ago, he just received a call from the hospital after lunch. Mr. Zhang can go to the hospital to test his lipids. He thought to himself why the hospital is so thoughtful. In the past, he never made a phone call in the hospital. Could it be a fraud?

He himself also has some doubts, why do he need to check blood lipids regularly after taking statins for a long time? Then he went to the hospital for examination and examination. After the results came out, he was relieved. He had no major problems and his blood value was kept within a safe range. The doctor also told him to check his blood lipids regularly, otherwise it might be of great harm to his health.

1

First of all, let’s learn about what statins are there? What are their functions and effects?

Currently, there are statins in China, such as lovastatin , simvastatin , pravastatin, fluvastatin , atorvastatin, rosuvastatin and pitvastatin , statins, i.e. 3-hydroxy-3 methylglutaryl Coenzyme A (HMG-CoA) reductase inhibitors, which can not only effectively reduce total cholesterol and low-density lipoprotein, but also reduce triacylglycerol to a certain extent, and increase high-density lipoprotein , so statins can also be called a more comprehensive lipo-regulating drug. The mechanism of action of

statins is to increase the amount and activity of LDL receptor LDL receptor hreflation by competitively inhibiting endogenous cholesterol synthesis and rate-limiting enzyme HMG-CoA reductase blocks the metabolic pathway of hydroxymethylvalerate intracellular, thereby reducing the synthesis of cholesterol intracellular membrane, thereby feedback stimulating the increase in the number and activity of LDL receptor on the surface of cell membrane, increasing serum cholesterol clearance.

1 level reduction is mainly used in clinical practice to reduce cholesterol, especially low-density lipoprotein cholesterol to treat atherosclerosis. It has now become the most effective drug for the prevention and treatment of coronary heart disease . Research has found that statins have many non-sauce effects, including inhibiting atherosclerosis and thrombosis, and also alleviating rejection after organ transplantation, treating osteoporosis , and anti-alzhes disease and other diseases.

. Rosuvastatin: Rosuvastatin is often used in lipid-lowering treatment for patients with mixed dyslipidemia and familial hypercholesterolemia .

2. Lovastatin: Lovastatin has the effect of reducing total cholesterol and low-density lipoprotein. In the treatment of patients with primary hypercholesterolemia, it can play a role in regulating blood lipids.

3. Simvastatin: When patients with hypercholesterolemia have poor dietary therapy, or if hypertriglycerideemia is combined, patients can take simvastatin orally for blood lipid-lowering treatment. This drug can also anti-artherosclerosis and has certain effects on the treatment of coronary heart disease.

4. Fluvastatin: For patients with primary hypercholesterolemia, fluvastatin can be taken orally to regulate blood lipid levels.

5. Atorvastatin: When patients with hypercholesterolemia have poor effect in non-drug treatment, oral atorvastatin can be improved. Note that common adverse reactions of statins include elevated liver aminotransferase, myalgia, myositis, rhabdomyolysis, etc. Patients with liver disease or kidney disease, as well as pregnant women and children, it is not advisable to use statins.

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st time to take statins? Doctor: Just follow this standard!

People who have just started taking statins should check blood lipids, aminotransferase and creatine kinase within 6 weeks of use. If the blood lipids can reach the target value and there are no adverse drug reactions, the gradual improvement will be made to be reviewed once every 6 to 12 months. If AST or ALT exceeds the upper limit of the normal value of three times, the dosage should be suspended.

and liver function still needs to be reviewed weekly until normal. If blood lipids do not meet the standard and there are no adverse drug reactions, monitor it every three months. For people who have been treated for 3 to 6 months, the blood lipids still have not reached the target value, so the dose or type of drug preparation needs to be adjusted, or other lipid-lowering drugs are used for treatment. Whenever the dose or type of drug adjustment is adjusted, the review should be reviewed within 6 weeks of treatment until the blood lipids meet the standard.

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How to prevent blood lipid increase in life?

. Persist in exercise: Persist in exercise can exercise, and it can play a preventive role in many diseases. In life, you need to persist in exercise for a long time to see the effect. It is recommended to exercise at least three times a week, and each exercise time is at least half an hour. You can gradually increase the exercise time according to your physical fitness.

2. Control your diet: In life, you should control your diet, reduce your calorie intake, eat less animal fat and high in foods, and try to be lighter in your daily diet. In addition, you should also eat more fresh fruits, vegetables and seafood.

3. Maintain a scientific lifestyle: In life, try not to stay up late, have a certain life pattern, and correct some bad living habits, such as smoking, alcoholism, etc.

4. Regular physical examination: For people over 40 years old, obese people need socializing in many things in their lives, and they are under great mental pressure, so they are prone to hyperlipidemia, so they need to go to the hospital for a regular physical examination.

5. Control the intake of salt: Control the amount of salt intake every day. If the taste is heavy, gradually reduce the amount of salt intake and do not consume more than 8 grams per day.