Question
How might genome editing be used to cure disease?
How will genome editing be used to treat diseases?
First explain the technical connotation at this stage. Genome editing uses CRISPR technology (the others are not reliable yet). Overall, this technology is still in the beginning of its treatment and disease development. Whether the method
is good or not requires a general judgment, and you cannot get into the details as soon as you start.
genome editing and treatment = repair the sheep without a sheep
Personal interpretation: The technology of repairing the sheep without a sheep is powerful, but it is not perfect. The reason is:
- is diagnosed with illness and then treated. The sheep will be repaired. It can only treat the body cells related to the disease. It can be used to treat the head and the foot pain. Disadvantages of
- genome editing: it requires complex operations and is basically impossible to treat in situ in the body. You can only remove - edit - and put back the target cells.
- target cells need to meet certain conditions: ensure a long life span, and it is best to continue to divide. bone marrow cells are almost the only target cell that meets the conditions more perfectly.
Last point, smart people must have thought that aren’t germ cells such as fertilized eggs more ideal?
Gene edited germ cells - Controversy
Unfortunately, gene edited germ cells are not considered a treatment in the conventional sense in the question.
But excluding these nouns, gene editing of germ cells is still a promising technology, but also controversial.
Perhaps someone still remembers that it is the scientist He Jiankui in Shenzhen, my country. He modified a gene of twin so that they can naturally resist AIDS after birth.
Basically, academic and society are unanimously criticized. Reasons include the risk caused by
- immature technology
- ethical and moral risks
So long has passed, and I will say that there should not be many people pay attention to the objections, huh. . Anyway, there are not many fans
- . Regarding the risk caused by immaturity of technology
New technologies have come from immaturity, and they are always verified by those who are brave enough to take the lead.
In fact, the new scientific theories are even the same. Helicobacter pylori was considered unable to exist with strong acidity in the stomach until Australian Barry Marshall drank Helicobacter pylori to prove that the bacteria can cause stomach disease.
We should encourage those who volunteer to take the risk, and those who are willing to take risks, rather than laugh at the risks they bring, after all, they have not forced you to use this risk technology.
Society should happily study their adventures carefully to truly benefit the public, rather than avoiding them like a plague.
- About ethical and moral hazard
Representative "People who want to change their health, stronger, more beautiful, and smarter can change their genes or their descendants. The social problems behind this will be immeasurable."
When a technology is not mature, they think about the harm it causes. It's like before the plane was developed, I thought he might be used to throw bombs.
far-fetched, far-fetched, far-fetched.
God: In this way, perfect humans are just around the corner, I don’t have to worry so much
Yunzhientropy: Without perfection, there will always be stronger, smarter, and more beautiful. Human dna is just a product of continuous repair in evolution, and it is not much perfect.
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