The pharmacological effect of small dose aspirin is to inhibit platelet aggregation. Platelet aggregation is the core step of thrombosis. Therefore, aspirin has the effect of inhibiting thrombosis and is used for the second-level prevention of atherosclerotic cardiovascular diseases such as coronary heart disease , ischemic stroke , and prevent the recurrence of these diseases. While aspirin prevents thrombosis, the most concerned adverse reaction is to inhibit platelet aggregation. The risk of bleeding is increased. In mild cases, subcutaneous and gingival bleeding, and in severe cases, gastrointestinal ulcers and bleeding. So, will aspirin cause cerebral hemorrhage ?
aspirin inhibits platelet aggregation, leading to coagulation dysfunction. Long-term use will slightly increase the risk of intracranial hemorrhage. Studies have shown that among the people taking aspirin, 12 cases of midcerebral hemorrhage increased in every 10,000 people. Cerebral hemorrhage caused by aspirin is related to the use of aspirin in large doses of people with poor blood pressure control and combined with other anticoagulants. It is also related to the patient's age. It is more likely to occur in elderly people. In order to avoid cerebral hemorrhage caused by aspirin, it is necessary to pay attention:
The risk of cerebral hemorrhage in the general population is relatively small, but patients with a history of cerebral hemorrhage should use aspirin with caution. The causes of cerebral hemorrhage are mainly related to arteriosclerosis caused by hypertension , and secondly, it is related to amyloidosis of cerebral artery . Therefore, the key point to prevent cerebral hemorrhage is to control blood pressure well. For patients with hypertension, long-term use of aspirin should be paid attention to controlling the blood pressure stability below 150/90mmHg, and then start using aspirin to avoid the occurrence of cerebral hemorrhage events. In addition, in some cases, when acute thrombosis events such as cerebral hemorrhage and myocardial infarction require anti-thrombosis treatment, a professional doctor needs to evaluate the risks of bleeding and thrombosis, and then decide after weighing the pros and cons. Ordinary patients cannot use aspirin without authorization.
In short, aspirin is a double-edged sword. While preventing thrombotic diseases, it can also cause bleeding in certain parts of the body, including cerebral hemorrhage, but cerebral hemorrhage is not a contraindication of aspirin. You can evaluate the risk of bleeding under the guidance of a professional doctor. We weigh the benefits or the risks, use them with caution and follow-up closely.
References
Guidelines for diagnosis and treatment of cerebral hemorrhage in China (2019)
Aspirin Antithrombotic Treatment Manual (2015)
#Cardiovascular Health Questions and Answers#
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