The quality of people’s diet is enriched with the improvement of living standards, but their diet structure is becoming more and more unhealthy Among them, intestinal polyps is a more frequent intestinal disease, , most intestinal cancer is caused by the pathological changes of intestinal polyps . As a gastroenterologist, many patients will consult me about intestinal polyps and intestinal cancer. I will briefly explain to you today.
What is the relationship between bowel polyps and bowel cancer?
Intestinal polyps is a common precancerous disease People with family history have a higher risk of cancer than ordinary people. Intestinal polyps are epithelial cell tumors, most of which are solitary and are distributed in the colon and rectum. Multiple polyps have family inherited factors . Therefore, there is a certain connection between intestinal cancer and intestinal polyps.
Because the size is different, the rate of malignant transformation is also different.According to the pathological type, it can be divided into neoplastic polyps and non-neoplastic polyps. Non-neoplastic polyps include inflammatory polyps, proliferative, and hamartoma-like polyps. Generally speaking, the probability of malignant transformation is particularly low. Neoplastic polyps are adenomatous polyps. Adenomatous polyps are classified into villous, tubular, and mixed according to their pathological types. The malignant transformation rate of each pathological type is different. tubular adenoma is relatively low, ranging from 1% to 5%. The malignant rate of villous adenoma is relatively high, ranging from 10 to 60%, and the mixed nature is between the two. has the most cancerous risk is Adenomatous intestinal polyp , mostly in the colon. The texture is crisp, so it is easy to be rubbed and bleeding. The number of can reach hundreds of thousands, which can occupy the entire rectum , so it is easy to cause cancer.
Therefore, intestinal polyps are closely related to colon cancer, rectal cancer and other intestinal cancers. Intestinal polyps are caused by the proliferation of stem cells in the intestine. The abnormal increase of intestinal stem cells is one of the factors of intestinal polyp carcinogenesis. A small number of stem cell markers can be checked in intestinal tumor.The appearance of these stem cells will proliferate abnormally, which leads to the resistance of cancer cells . Therefore, the detection of intestinal cancer stem cells is of positive significance for diagnosis and treatment. Early intervention of cancer stem cell proliferation by can target to treat intestinal cancer.
Intestinal polyp carcinogenesis signal
Intestinal polyp
Intestinal polyp carcinogenesis signal
Intestinal polyp 1span intestinal cancer_spanspanspanspanspanspanspanspanspan3 During the initial onset, there is no unusually obvious pain, so it is difficult for patients to detect it. In clinical practice, bowel cancer is divided into 1-4 phases , and actively cooperate with treatment in 1-2 phases. A higher cure rate can be obtained. Although has early stage bowel cancer and will not has significant abnormal symptoms,But as long as you observe carefully, you can still find some signs of intestinal polyps canceration.
●Blood in the stool
Chinese medicine believes that the occurrence of intestinal polyps is caused by the depression of the intestinal damp heat and poisonous gas in the intestine, which causes the strong_strong span1 in the intestine to be blocked by the intestinal gas circulation. , easy to cause meridian stasis, congestion and turbidity, constipation or diarrhea in the light, the loss of the internal organs, , intestinal ulcer bleeding . There are no obvious symptoms in the early stage of intestinal polyp canceration. Most of the symptoms are abdominal pain, diarrhea, pus and blood in the stool, tenesmus, a feeling of falling abdomen, melena, weight loss, fatigue, blood in the stool and other symptoms. The color of blood in the stool is bright red, which may be dribbling or spray , large amounts can cause anemia, and blood in the stool is often present on the surface of the stool. If the intestinal polyp grows at the lower end of the rectum, will protrude out of the anus during defecation, and sometimes it may need to be lifted with fingers.
The amount of blood in the stool is related to the degree of friction and rupture of the tumor blood vessels.The continuous proliferation of tumor cells requires the intake of nutrients from the patient's body , when the patient lacks nutritional support, anemia will also occur. People who usually work and eat irregularly are prone to symptoms of constipation and blood in the stool. When constipation requires exertion, huge abdominal pressure can also compress the intestines, resulting in blood in the stool If you have to go to the hospital for treatment in time after the occurrence of blood in the stool, in addition, in the process of treatment, you need to follow up in time if the condition is repeated.
In addition, if you find that your bowel habits and stool shape have changed, such as stool becomes thinner, thicker, the number of bowel movements increases or decreases, mucus is attached to the stool, and the stool feels difficult to pass If there is a feeling of drape in the abdomen, such as , etc., you must also be vigilant. It may be a precancerous signal.
● Long-term diarrhea _strongGastrointestinal health needs to be adjusted as soon as possible. If the symptoms are still not resolved after the conditioning, further examination is required. If it is accompanied by abdominal pain, anemia, and , there is a lump in the abdomen. Foreign body sensation , colonoscopy is recommended, at this time the intestinal polyps may have become cancerous. In addition, if has undergone polyp surgery , it is recommended that should be regularly checked for CEA, CA19-9 and other cancer antigen indicators if there are indicators that are elevated, polyps need to be considered Cancerous.
When the above symptoms occur, seek medical attention as soon as possible. For those with a family history, they should also be reviewed regularly. Circumstances, the early stage bowel cancer can be detected as soon as possible. Once diagnosed, treatment should be done as soon as possible. Do not delay .
through colonoscopy,Facilitate the diagnosis of bowel cancer
Colonoscopy can more intuitively reflect the condition of bowel disease. Even after other tests, the final diagnosis needs to refer to the colonoscopy test report. The colonoscopy at this stage can expand the field of view of several times , and can clearly observe the small changes in the bowel cancer tissue and intestinal mucosa with the naked eye. At the same time, colonoscopy can also be performed. During the examination, clamped the suspicious tissue , and then sent to the pathology department for related examination. Therefore, colonoscopy is helpful to find abnormal signals in the pre-cancerous stage of intestinal polyps and facilitate the diagnosis of intestinal cancer.
Tumor cells of early bowel cancer grow on the inner wall of the intestine, and there is no metastasis or infiltration temporarily. At this time, it is convenient for treatment. Usually for early stage 3span strong surgery For treatment of , the cancerous tissue will be removed; if it is 2, stage 3 cancer, it also needs to be treated by surgery + chemotherapy _strong7 span3span _strong7span3span _strong7 Phase 4 needs to pass targeted therapy drugs ,Inhibit the growth of cancer cells to prolong the survival of patients. The mechanism of the drug is to attack cancerous blood vessels and tissues, so that new cancerous blood vessels are inhibited, and the rate of shrinkage is accelerated. and chemotherapy methods for treatment will help destroys cancerous cells , cuts off the signal of cancer cells to attack healthy cells, and allows healthy cells to gain more lasting resistance, thereby reducing the chance of cancer metastasis .
should be checked as soon as possible after intestinal polyps are found to rule out cancer. If intestinal cancer is diagnosed, it should be treated actively to prevent the cancer from getting worse. In addition, in order to prevent intestinal polyps from becoming cancerous, you should usually eat more fresh fruits and vegetables . These foods are rich in vitamins and fiber, which are beneficial to intestinal peristalsis and prevent constipation; reduces Ingest fried, spicy, pickled and other foods to avoid burdening the intestines; maintain good bowel habits and have regular bowel movements. Do not use excessive force during defecation So as not to increase the pressure of the intestines, forcing the intestines to fall outside, increasing the chance of blood in the stool. In normal life maintain a healthy schedule can enhance immunity and resistance, and reduce the chance of healthy cells being attacked by cancer cells.
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