When storing insulin preparations, avoid placing them in the freezer, or near the freezer. Because insulin crystals or particles tend to condense when frozen and form larger particles or blocks, these will not disappear due to dissolution. For premixed preparations or medium-acting insulin preparations, this change means that the uniform suspension will no longer exist. Therefore, even if the exact volume is drawn or used, the dose of insulin used may still be too large or too small. Therefore, frozen insulin preparations cannot be used again even after thawing.
Whether it is a bottled insulin preparation or an insulin refill, when using and carrying these devices, they are often packed in pockets, so the stored temperature is very close to body temperature. Bottled insulin preparations can be stored safely for about 6 weeks at room temperature (about 25℃), and the insulin refill can be stored for 4 weeks. Therefore, the storage environment is very important to ensure that the insulin preparation has a complete biological effect.
storage temperature will cause the biological effect of insulin preparation to gradually decrease. At the same time, some visual changes may occur, which are closely related to how high the storage temperature is and how long it is stored at this temperature. For example, clear soluble insulin preparations can precipitate, causing them to appear floc; while floc-like insulin suspensions can appear larger particles or clots. Excessive storage temperature, sun exposure or long-term sun exposure, excessive shaking or vibration insulin preparations will accelerate the occurrence of the above situations and ultimately affect the sugar-lowering effect of insulin preparations.
In order not to affect the effect of insulin lowering sugar, it is very important to store correctly. When storing, please note:
(1) Store insulin between 2℃ and 8℃, preferably in the refrigerator. At this temperature, insulin preparations maintain their biological effects and antimicrobial effects until their expiration date.
(2) If there is no refrigerator, it can be placed in a cool and light-proof place, but it should not be placed in direct sunlight or in a high temperature to prevent failure.
(3) Insulin Pen cannot be stored in a refrigerator during use.
(4) Avoid shaking or vibrating the insulin preparation for too long.
(5) When traveling by plane, insulin should be carried with you and should not be placed in checked luggage, because the checked luggage temperature is below the freezing point. If you travel for less than 1 month, you can not leave it in the refrigerator. However, the bottle should be avoided from being exposed to special environments such as sunlight, high temperature or too low temperature, especially in such environments for a long time. If you are staying in the hotel and other places, it is best to store insulin in the refrigerator.
