Some people regard cholesterol as a disaster, but it is an essential nutrient in the body, involved in cell production and maintain bile and hormone synthesis. However, high cholesterol can enter the blood vessel wall, prompting the generation of atherosclerotic plaques, thereby causing acute myocardial infarction or cerebral infarction , etc. In addition to harming the heart and brain, high cholesterol can also harm the liver and kidneys.
What parts will high cholesterol harm?
, heart
low-density lipoprotein cholesterol is called bad cholesterol. Elevated levels of bad cholesterol in the blood can damage the endothelium of the blood vessels. Atherosclerotic plaques can be generated on the wall of the blood vessels. The plaques will gradually become larger, and the blood vessels will become narrower, which will eventually induce stroke or coronary heart disease , etc. After plaque rupture, it is easy to cause thromboembolism, easily block blood vessels, causing acute myocardial infarction, or cerebral infarction, , and even threatening life.
2, brain
itself contains a lot of cholesterol, but patients with hypercholesterolemia have a high risk of cognitive impairment in . Because the body has biochemical reaction disorders, it is impossible to remove excess cholesterol from the brain normally, destroy the integrity of the blood-brain barrier, and cannot remove amyloid in the brain, thereby inducing Alzheimer's disease . In addition, too much cholesterol accumulation in neurons can easily cause degenerative changes in neurons.
3, kidney
too much cholesterol is stored in the body. Cholesterol is easy to deposit in renal tubular and glomerular epithelial cells . If it continues for a long time, it can induce chronic kidney disease , and in severe cases, it can cause renal insufficiency.
4, thyroid
Too much cholesterol accumulates in the thyroid gland and pituitary , which can easily lead to dysfunction of the pituitary-thyroid axis. Studies have shown that hypercholesterolemia is a high risk factor for hypothyroidism, so blood lipids and should be actively controlled, and statins should also be taken if necessary.
5, bone
vitamin D synthesis cannot be separated from cholesterol, but too much accumulation can easily cause bone diseases, such as osteoporosis and osteoarthritis , etc. High cholesterol can cause oxidative stress in in , which promotes mitochondrial apoptosis, leading to a large amount of bone loss in the cartilage, thereby causing osteoarthritis.
6, pancreatic
Pancreatic B cells can secrete insulin , which is the only hormone in the body that can regulate blood sugar. Too much cholesterol accumulates in pancreatic islet B cells, hindering glucose metabolism, destroying the cell structure , thereby causing functional disorders and also prone to induce diabetes .
Warm reminder
High cholesterol can also damage the liver. Cholesterol is metabolized in the liver. Excessive cholesterol can exceed the range that the liver bears. Over time, fatty liver can cause damage to liver function; high cholesterol can also damage the immune system and reproductive system. Therefore, cholesterol should be actively controlled. The daily cholesterol intake should not exceed 300 mg. Eat more fresh vegetables and fruits, maintain moderate exercise, and go to the hospital for examination regularly.
online special article for family doctors, no reprinting without authorization
