Last week, the hot search list was dominated by Wang Xiaofei for a day, even more popular than the World Cup.
it turned out that Wang Xiaofei was kicked out by a magazine and did not pay the 5 million living expenses for the divorce agreement with her ex-wife big S ( Xu Xiyuan ). She was so angry that she posted a message continuously and reported that her former sister-in-law little S (Xu Xidi) had been abused by sleeping pills " Sinuosi " for many years. She had to take 20 pills a day without the doctor's prescription and took the medicine through a third party to get the ID card.
So, Sinos became popular as well. The people who had insomnia problems immediately thought that it would help treat insomnia, so they asked to buy offline, and even asked the doctor to prescribe Sinos during outpatient visits.
What are the characteristics of Sinos that make him famous overnight? Is it really not addictive? What should you pay attention to when eating it?
third-generation hypnosis
According to clinical statistics, the global prevalence of insomnia is as high as 35%, of which nearly 17% of patients have been seriously affected. Elderly, women, mentally ill, chronically ill, and people with low socioeconomic status are most susceptible to insomnia.
Traditional treatment for insomnia often uses benzodiazepine drugs, such as diazepam (first generation), alprazolam (second generation), etc., but these drugs will cause damage to the patient's psychomotor and cognitive function, and the effects and side effects are not ideal.
, and zolpidem tartrate (Sinos) is a non-benzodiazepine sedative sleeping pill, which is a third-generation hypnosis pill. Compared with benzodiazepine sedatives, it has the characteristics of rapid absorption and rapid onset of action. Its oral bioavailability is 70%, and the blood drug concentration can reach its peak 0.5 to 2 hours after oral administration, and its effect can be maintained for 6 hours. Therefore, it is used in clinical practice to treat severe insomnia in the case of occasional and temporary insomnia.
In general, as a hypnotic pill, Sinos falls asleep for a short time, almost "falls when you take it". Moreover, there are fewer wakes up at night, which can increase the total sleep time. The most important thing is that after waking up, there will be no fatigue side effects of "not waking up" and "not enough sleep" after waking up, which can greatly improve the quality of sleep and can be regarded as a relatively ideal hypnotic pill.
But it should be emphasized that Sinos is indeed relatively small in addictive, but it is not completely non-existent. It is still possible to become addicted after taking it for a long time!
What should I pay attention to when taking Sinos?
First of all, Sinos has a short half-life and is absorbed quickly after oral administration. Although this is an advantage and a disadvantage, many people will fall when walking because they get out of bed after taking the medicine, especially the elderly.
Therefore, before taking the medicine, you must wash, empty your urine, prepare warm water, and ensure that you lie down immediately after taking the medicine. You must also ensure that there is no human interference within 4 hours after taking the medicine. If you take the medicine before you are ready to sleep, the patient will soon enter a subsleep state, and the medication will cause side effects such as vertigo, hypostasis, ataxia, etc., and various accidents may occur. For example, some patients in clinical practice did not lie down in time after taking Sinos, and became dizzy and fell down during the washing process.
Secondly, try to take the medicine in small doses, especially for those with organic brain diseases. The starting dosage should start from 5 mg and not exceed 10 mg. For individual elderly patients with poor low doses, be cautious when increasing the dosage of the medicine to observe whether there are adverse reactions. For example, after the clinical patient increases from 5mg to 10mg, he has an illusion at night, and sees other people's heads getting bigger, and feels scared and screams loudly.
dosage recommendations for zolpidem: ① The commonly used dose for adults is 10mg/day, and the daily dose shall not exceed 10mg. Take it before going to bed or after going to bed, once a night, and do not take it multiple times; ② The elderly or frail patients start from 5mg, and the daily dose shall not exceed 10mg; ③ Patients with mild or moderate liver injury shall not start from 5mg, and patients with severe liver injury shall avoid using it.
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Third, the course of medication depends on the type of insomnia. For occasional insomnia, the course of medication is generally 2 to 5 days; for temporary insomnia, the course of medication is 2 to 3 weeks; the course of medication should be as short as possible, with a maximum of no more than 4 weeks; medications will increase the risk of addiction; when the course of medication exceeds 6 months, the medication must be changed.
Fourth, Sinos' medication methods are divided into continuous treatment and on-demand treatment: taking one time before going to bed every night is called continuous treatment; taking 3 to 5 times per week according to sleep needs is called on-demand treatment. Although the instructions say that both methods are OK, studies have shown that the two methods have similar efficacy and the drug resistance and addiction caused by on-demand administration are less likely to occur.
In addition, when patients with insomnia have not yet experienced any remission after using Sinos for 7 to 10 days, it is suggested that there may be mental illness or other physical illnesses. The doctor needs to re-evaluate and diagnose it, and change the treatment plan if necessary.
What to do if you become addicted to sleeping pills?
Because many insomnia are chronic, many patients often need to take sleeping drugs for a long time. There are two types of addiction to sleeping pills. One is psychological dependence. For example, some people must take it once a night, but they cannot sleep once they don’t take it, but the dosage remains unchanged, which is psychological; the other is physical dependence, that is, the dosage of the medicine is getting bigger and bigger and uncontrollable.
Sleeping pill addiction is a common concern. It can be said that any sleeping pill is more or less addictive. Sinoth is not very addictive, but there are also reports of addiction.
In response to this situation, it is not clinically recommended that patients take a sleeping pill for a long time. It is recommended that the time for taking a sleeping pill should not exceed 4 weeks. If you still have insomnia, you should change to another sleeping pill. There are many types of sleeping pills. By changing one medicine at a time and avoiding taking one medicine for a long time can reduce the possibility of drug addiction.
In addition, insomnia is a disease related to various factors such as living habits, psychological stress, and mental state. Patients should try to use green therapies such as regular life, proper exercise, and psychological adjustment to achieve the purpose of reducing or curing insomnia.
For example, regardless of insomnia or not, you must get up at the specified time and do not stay in bed; the nap time is best within half an hour, and it cannot be too long; you can perform appropriate physical exercise in daily life, which can not only relieve mental stress, but also cause the body to feel tired and help you fall asleep; do not use electronic products before going to bed to reduce the effect of blue light ; when you can't sleep, you can get up and do something else, don't insist on lying in the bed, etc. #Wang Xiaofei##Insomnia#
