At the end of 2019, a new strain of virus set off an unprecedented crisis around the world. People all over the world were panicked. Even the World Health Organization said: This is a difficult challenge that mankind must face!
On February 11, 2020, this virus officially had a name: 2019 coronavirus! As the virus continues to mutate and its harmfulness continues to decrease, countries around the world have also relaxed their prevention and control efforts, and many countries have even completely relaxed their control over the new coronavirus!
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The relaxation of control means that everyone must fight the virus head-on, and soon someone discovered that ibuprofen seemed to have a certain effect in fighting the new coronavirus. Over time, ibuprofen was even rumored to be a "miracle drug" against the new coronavirus.
What is little known is that as early as the 1960s, ibuprofen had been successfully launched, and it was just a small piece of ibuprofen that not only brought the British BOOTS company back to life, but also achieved an annual revenue of nearly 10 billion!
So, who was the inventor of ibuprofen? How did he successfully develop ibuprofen in the first place? Is ibuprofen really effective in fighting the new coronavirus?
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Ibuprofen made a hangover and lost money without making a penny
In addition to the users of ibuprofen, Stuart Adams may be the only person who lost money for ibuprofen , because when he applied for a patent in 1962, Adams paid a registration fee of one pound, and Boots did not "reimburse" him for this money.
As the inventor of ibuprofen, one pound is naturally not a fuss, but a sense of humor unique to Adams. After all, who would have thought that the birth of ibuprofen, which would become popular all over the world and save countless people suffering from bone-eroding pain, was actually thanks to a hangover .
Adams
In 1923, Adams was born in a family of railroad workers in England. When the children looked up, they saw a helpless father. What the father looked down at were five children who were waiting to be fed. Adams grew up in such an environment with difficulty.
lasted until he was sixteen, but the family really couldn't supply it anymore.
When he left home to work as an apprentice in a retail pharmacy, Adams realized for the first time that his father was old. His sideburns had grown gray hair at some point, and his handsome and upright figure had slightly bent his legs at some point.
Adams
noticed his son's gaze. The father who was sitting in the chair wanted to stand up and tell Adams something, but years of overloaded and heavy work overwhelmed his body. When he got up, he subconsciously touched his painful knees.
This moment deeply hurt Adams' heart. He began to want to find a drug to treat rheumatoid arthritis that did not have strong side effects like aspirin, for his father and for all the people in the world who needed pain relief.
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The young man has great ambitions, and it is 's "old club" Boots that helps him take off. The pharmacy where Adams was an apprentice was owned by Boots. After three years of training, Adams became an excellent pharmacist.
's unmistakable brilliance made Boots discover this talent. After learning of Adams's lofty ambitions, he directly paid all the expenses for him to complete a bachelor's degree in pharmacy at University of Nottingham .
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The dual drive of ideals and abilities put Adams' life on the fast track, and the joining of John Nicol and Colin Burrows made it even more powerful. The three people are united and firmly believe that they can achieve their goals and create miracles that shock mankind. However, they fail time and time again.
John Nicol
When the research was going crazy, the three of them would even test the properties of the medicine directly on themselves.
But even with such efforts, ten years later, the three of them are still unknown. The extremely frustrated Adams entered a pub one night obsessed with it. He wanted to have a drink to numb his tense nerves, but he forgot to read the sentence "Pure Vodka" on the sign when he entered.
The strong alcohol made his body warmer and warmer as he drank. Adams was swaying when he walked out. He didn't know how he would get home, but the splitting headache after he sobered up was a real feeling, because it made him almost unable to get out of bed.
In desperation, Adams thought that the new painkiller drug developed some time ago happened to be available at home, so he took it with warm water. Unexpectedly, the effect of this drug was very obvious, and Adams's head pain soon stopped.
After rigorous and meticulous testing by a small team of three people
, a special medicine was born. Overwhelming reports poured into the three of them. At the night when the bustling scene was over and the familiar darkness once again enveloped the three of them, Adams said self-deprecatingly, "No one paid attention to scientific research in the past ten years, but once I got drunk, it made everything possible for you and me. Life is really full of variables."
said such "sardonic words" not because Adams did not know how to be satisfied, but because he regretted that not all scientific researchers were as lucky as himself. This is why chose to achieve ibuprofen, but refused to let ibuprofen achieve his .
Save people from pain and fever, and save the company from the dead
Although the original intention of Adams' research was to find drugs that could replace aspirin in the treatment of rheumatoid arthritis, the final result was an off-track painkiller, but this was not the main reason why Adams gave up on the wealth and prosperity at his fingertips.
Adams
He simply wants to benefit more people.
The huge revenue could not be stuffed into Adams' pocket, but for Boots, the "raw jade" they discovered early gave the company a new lease of life.
As a century-old health and beauty drug store with a high reputation in the UK, Boots, founded in 1849, has proven the importance of foresight with its strength.
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In 1939, no one would have believed that Adams, who dropped out of school, had the ability to become the future "Father of Ibuprofen" . It was Boots who taught him his skills as a pharmacist and sent him to a high-end institution for further study. During the ten-year attempt of the three-person team, which had not seen the light of day, it was Boots who used the turnover to cover the scientific research expenses of the three people.
Without Boots, Adams might not have survived the hangover day in 1961, and it would have been impossible for ibuprofen to be patented in 1962 and approved as a prescription drug seven years later.
Adams, who dedicated his youth and dedicated himself, received an honorary doctorate in science from his alma mater, the University of Nottingham, and was awarded the Order of the British Empire by the Queen of England in 1987. Adams, who did not seek wealth and wealth, gained "fame", and "profit" fell on Boots.
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I can only say that the emergence of ibuprofen is timely.
As a family-run herbal pharmacy, Boots was small at the beginning. Even though it had ambitions to become bigger and stronger, the ups and downs of the mall require not only a down-to-earth attitude to work, but also marketing.
Boots did not have the money. Apart from the expenses to support scientific research, the dismal revenue once made Boots think that it would close down in the next second. Fortunately, they finally survived until ibuprofen was released. Seeing that the opportunity to turn around was just around the corner, the British Medicines Safety Committee gave it another fatal blow in August 1978.
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That was when Boots applied for the first time to put ibuprofen on the market, but was rejected.
A product with no market value is no different from the exquisite ornaments in the window . Ten years of hard work cannot be ruined by one rejection, so in April 1982, Boots applied again and made ibuprofen an over-the-counter drug.
This time, Boots finally won.
In August 1983, ibuprofen began to be sold in the British market. After the recovery, Boots also began to "expand" in the United States and other places. opened up the market of sold around the world, and directly jumped from the verge of bankruptcy to an annual revenue of nearly 10 billion.
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According to incomplete statistics, as the world's best-selling painkiller, the annual demand for ibuprofen can reach 20,000 metric tons. According to data from the "China Pain Medicine Development Report", there are more than 300 million chronic pain patients in my country alone, and the number is still growing at a rate of 10 to 20 million every year.
As the number of patients increases, the demand for ibuprofen will naturally increase. But in fact, in the early 1990s, global sales of ibuprofen preparations had exceeded the $1 billion mark.
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As a dark horse among antipyretic and analgesic drugs, ibuprofen has become a "life-saver" and "life-saving tool" in public opinion. This phenomenon has reached a new peak after the emergence of the new coronavirus. Even if factories work overtime for production, many places are still hard to find a single drug. What is going on?
One drug is hard to find, ibuprofen has become the last battle
After the new coronavirus visited the earth in 2019, the global economy fell into a "strange circle" . Everyone is lamenting that the industry is not easy to develop, and the economy seems to have been pressed on the pause button.
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It is not surprising that physical stores have been closed in the past few years during the epidemic. But what is surprising is that the shelves of ibuprofen in pharmacies are empty most of the time. Some pharmacies even state that "each person can only buy one box" in order to avoid consumers' rush.
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In fact, there is no need to rush and hoard goods.
People do this just because they think that if they are unfortunately infected, they can relieve their physical pain, because ibuprofen can reduce fever and pain and has fewer adverse reactions. Of course, this idea is understandable, and the significance of medical progress is precisely to reduce the pain of patients.
Everyone knows that when the immune molecules in the body fight against the virus after being positive for COVID-19, the body temperature will rise. The body needs drugs like ibuprofen to reduce fever. Protection can be provided, but excessive protection is not advisable.
COVID-19 positive fever and headache usually last for about four days. According to the dosage of two pills a day, a person only needs 8 pills of ibuprofen at most to get through the recovery process.
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Even if China has a population of more than 1.4 billion, the output of China's pharmaceutical industry can definitely keep up.
Starting from December 17, 2022, Wuhan has released 3 million tablets of ibuprofen every day for a week, and 1.1 million tablets of ibuprofen in Jinan have also been delivered to medical institutions. The output of ibuprofen granules in Zhejiang can reach 40,000 boxes per day.
All companies are trying their best to dispel the public's panic with a "stop people but not machines" attitude, and "health packs" containing ibuprofen in many places have been delivered to patients as soon as possible.
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Anti-epidemic drugs are being produced continuously. In the last battle against the epidemic, the country is still everyone's backing. You must know that it was Adams who invented ibuprofen. With this annual revenue of nearly 10 billion, it is the British Boots, but the world's largest manufacturer of ibuprofen API is in China, and its name is Xinhua Pharmaceutical .
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China will always be the confidence of all Chinese people, so don’t panic when something happens, there will definitely be medicine. What is more important than buying medicine is actually taking medicine.
As an anti-inflammatory drug , ibuprofen must not be taken with alcohol, which will increase damage to the liver. The much-hyped ibuprofen is not a panacea for pain relief. The inflammatory pain and gastrointestinal spasm caused by bacteria is called " negative feedback ".
It is normal for the masses to panic about the virus, just like Adams felt despair in the ten years of darkness with no end in sight. However, the country has taken ninety-nine steps, and what this last bravery requires is the firm step of all citizens.
Adams' ten years of dormancy finally yielded results, but he still remained calm and left interests behind; a little ibuprofen allowed Boots to make tens of billions a year and enter the ranks of winners, but it did not avoid the difficult muddy road.
We always feel at ease with gifts and protection, but why do we complain so much about risks that we should have accepted long ago?
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Everything will pass, like boots on the verge of bankruptcy, like Adams' scientific research experiments that have disappeared into the sea.
The new coronavirus began to spread in December 2019, but on January 30, 2019, Adams, the "father of ibuprofen," passed away. Many people regretted that he did not see the "peak age of demand" for ibuprofen, but Adams would never want to see a day when it is difficult to find a drug. A world without disease and disaster is the prosperous age in Adams' heart.
The break of dawn is the final game between darkness and dawn . When the time comes, the rising sun and hope will surely warm all new lives. This day is coming.
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