Prenatal screening for Down syndrome yesterday my sister-in-law called and said she had just had a Don screening for the fetal screening. The doctor said that the value was at the critical value. The little girl cried after hearing this, saying that the child could not be asked f

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Prenatal screening test for Down syndrome

Yesterday my sister-in-law called and said that she had just had a fetal screening test. The doctor said that the value was at the critical value. The little girl cried after hearing this, saying that the child could not be asked for it anymore, and she was afraid that there was a risk of deformity.

I felt it was a bit exaggerated after hearing it, so I quickly asked her to send a check report to check it out. When I saw it, I suddenly realized that it was the little girl who didn’t understand what Tang Si was like at all. In addition, our Chinese language is profound and profound, and there are several ways to express the same meaning, which is particularly easy to cause misunderstandings.

Today, teacher Tina will talk about Down’s screening.

What is Down's screening?

The full name of Down screening is Down syndrome prenatal screening, generally referred to as Down screening.

simply means to determine whether the fetus suffers from congenital silence and neural tube defects and other diseases. Through the test, the probability of the above problems in the mother's womb is measured.

In a word, how old are you likely to give birth to a baby in Down?

When will pregnant mothers do Tang Screening?

is usually the 16th week of pregnancy when the doctor recommends a Tang screening test.

What is the principle of Down's screening inspection?

We have two chromosomes in normal human cells, but some babies have three chromosomes in their cells.

If the extra chromosome occurs in the

3 pair, we call trisomy 13; if it occurs in the
8 pair, it is called trisomy 18.

most commonly occurs in pair 21, called 21 trisomy syndrome . That is what we call Down syndrome.

Unfortunately, babies with trisomy 13 and trisomy 18 rarely survive.

However, babies with 21-body syndrome can not only survive, but the latest scientific research shows that through early intervention and guidance, Down's babies will become more of a blessing rather than a burden.

What will happen if my mother is a high-risk group?

Doctors may recommend that pregnant mothers do further amniotic fluid puncture test. Let’s not talk about whether amniotic fluid puncture is necessary. First of all, everyone must know what amniotic fluid puncture is.

Amniotic fluid apnea

Draw amniotic fluid: Take 20ml of amniotic fluid, the risk is possible infection, amniotic fluid leakage, and miscarriage.

Cell culture: Cultivate cells that have fallen off in amniotic fluid, with a success rate of 98/100.

test cell: test chromosomes in cells, with an accuracy rate of 100/100.

Should pregnant women undergo amniotic fluid puncture?

Here we quote a passage from Dr. Sears, a world-renowned professor in the field:

"For mothers over 35 years old, the risk of miscarriage caused by amniotic fluid puncture is equivalent to the risk of giving birth to a baby with chromosomal defects; depending on your unique pregnancy and childbirth situation, you should discuss the pros and cons of screening with your doctor. Generally, the probability of miscarriage after amniotic fluid puncture is 1:200, and you should ask your doctor about the risks when doing this surgery Probability, whether to do it or not, it will be necessary to make the decision whether to perform amniotic fluid puncture. "What are your feelings after reading it, or have any doubts, please tell Teacher Tina in the message

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Why does the baby suffer from Down syndrome?

In addition to genetic factors, the most common one is related to the age of pregnant mothers:


htm3htm15htm0Age of expectant mothers



htm0htm1The probability of a baby suffering from Down syndrome


htm020 years old


htm01:1667


30 years old


1:952


35-year-old


1:378


40-year-old


1:106


45-year-old


1:30

The older the age, the greater the probability of it happening, but this does not mean that it will happen.

If you are pregnant at the age of 35-40, you may be worried about whether you will give birth to a Down baby. If we look at the statistics together, we will know that it is not that scary.

Statistics show that: Although pregnant mothers aged 35-40 have a Down baby more likely than people aged 20-30, and from the data, it is really much larger;

But in itself, she has

9.5% of the probability of giving birth to a baby with a completely normal chromosome, which seems to be very likely to win.

However, it can also be seen from the above data that the risk of pregnant mothers in will increase a lot after

0 years old. Therefore, doctors are legally obliged to inform pregnant women over 35 years old that such Down screening is required before delivery.


Is Down syndrome really that scary?

Since it is a probability problem, the result must not mean " will or will not be able to "

In order to facilitate everyone's understanding, I will pass on the results of my younger siblings to everyone:

My younger siblings are 25 years old this year, and the result is measured at 1:1140. The report results are very clear: First of all, this value expresses the risk, and it must not be a specific conclusion. Although her value is close to the standard line in , it is still below the standard.

So the conclusion is: Down's risk does not exceed the screening standard and belongs to the low-risk group.