Source: CCTV News Client
my country has started to receive the new crown vaccine in December last year. As of now, the total number of new crown vaccines has been vaccinated with nearly 2.4 billion doses, and the vaccination rate of the entire population is leading the world. Clinical research results show that my country's new crown vaccine has good safety and effectiveness. Zheng Zhongwei, head of the Vaccine Research and Development Special Team of the State Council’s Joint Prevention and Control Mechanism, responded to some hot issues regarding vaccination in an exclusive interview with CCTV reporters on the Central Station.
my country's new crown vaccine has good safety and effectiveness
At present, 13 new crown vaccines in my country have entered Phase III clinical trials, 4 new crown vaccines have been approved for conditional marketing, and 3 new crown vaccines have been approved for emergency use. Vaccine research and development and production have always been in the world's first echelon. At the same time, my country has used the new crown vaccine as a global public product and has provided more than 1.7 billion doses of the new crown vaccine to more than 110 countries and international organizations in the world.
Head of the Working Group of the Scientific Research and Development Group of the State Council’s Joint Prevention and Control Mechanism Vaccine R&D Special Team: China’s new crown vaccine has made China’s contribution to the global COVID-19 prevention and control, and has made due contributions to the WHO’s goal of achieving global vaccination by the end of this year and the goal of achieving global vaccination by the middle of next year.
clinical research results show that my country's new crown vaccine is safe and has low side effects in more than 1 billion doses of vaccination in countries with high epidemics abroad and more than 2 billion doses of vaccination in domestic countries. For example, the proportion of fever after vaccination is 1761/1 million, which generally does not need to be treated; severe allergic reactions are less than one in ten million, and as long as they are treated in time, there is no major problem. Overall, the safety indicators of the new crown vaccine currently received in my country are better than the various vaccines received in normal years.
China's new crown vaccine has significant effects on preventing severe illness and death
Home and foreign research data have proved that my country's new crown virus vaccine has certain effects on preventing infection, has significant effects on preventing severe illness and death, and has protective effects on all mutant strains.
Zheng Zhongwei believes that humans' historical experience in controlling infectious diseases such as smallpox, measles, diphtheria and other in shows that vaccines are the ultimate weapon to defeat infectious diseases. Foreign real-world research has verified the effectiveness of my country's new crown vaccine. A Chilean Ministry of Health adviser recently published the world's largest real-world study of the world's largest new crown vaccine of 10 million people in the New England Journal of Medicine, showing that 14 days after receiving the second dose of Sinovac's inactivated vaccine, the overall protection is 65.9%, and the protection against hospitalization, severe illness and death is 87.5%, 90.3% and 86.3% respectively. According to a report by the Peruvian Ministry of Health, 60,593 doctors received the inactivated COVID-19 vaccine from Sinopharm Group China Biologics, of which the mortality rate of completing two doses of vaccination was reduced by 98%. The Argentine Ministry of Health issued a report that the overall mortality protection rate of people over 60 years old was 84% after receiving two doses of Sinopharm Group's inactivated COVID-19 vaccine. Sri Lanka's research report on the effectiveness of Sinopharm China Biotech's new crown inactivated vaccine shows that the antibody titers of vaccinated patients for the delta strain have only dropped by 1.38 times, and it still has good protective effect on the delta strain.
Head of the Working Group of the Vaccine Research and Development Special Team of the State Council’s Joint Prevention and Control Mechanism Scientific Research and Development Group: In China, some epidemics that occurred last year and this year can also make such judgments. Since the Guangdong epidemic began in May and June this year, the main virus strains that are popular in our country are Delta strains, from Guangdong, Jiangsu, Fujian to Inner Mongolia, Gansu, Qinghai, etc. Although there are many outbreaks, the number of people we infected and the number of severe cases is completely different from the epidemics in Xinfadi, Beijing and Shijiazhuang Gaocheng, Hebei last year. Therefore, the country has quickly promoted large-scale vaccination of people since this year, which should be said to have played a very important role.
Zheng Zhongwei introduced that domestic real-world research has also verified the effectiveness of my country's new crown vaccine. There are epidemics in Jiangsu and other places. As of August 25, a total of 1,388 infected people were reported, all of which were infected with the Delta strain. According to preliminary analysis, only 5 of the infected people who had been vaccinated for 14 days after two doses developed severe illness, accounting for about 5% of all severe cases. 97% of the severe cases over 60 years old had not been vaccinated or had not completed two doses of vaccination.A study on the protection effect of vaccines in the epidemic in Guangdong led by Academician Zhong Nanshan shows that the protection effect of two inactivated vaccines in Sinopharm Zhongsheng and Sinovac can reach 70.2% and the protection effect of severe cases is 100%. Even if it develops into severe illness, most vaccinated patients can turn to normal in the short term.
my country has completed preclinical research on the inactivated vaccine of Delta strain
At present, various vaccine research and development units have carried out a series of work on various mutant vaccines, among which preclinical research and development of the inactivated vaccine of Delta strain
Real-world research shows that my country's vaccines have clear effects on infection and post-infection caused by various major variants prevalent in different regions, and have significant effects on preventing severe illness and death. Overall, the mutation of the new coronavirus is relatively stable. Judging from the recent domestic sporadic epidemic, domestic vaccines are still effective against the Delta strain. However, in order to be prepared for any accidents, various vaccine research and development units have carried out a series of work on various mutant vaccines.
has completed preclinical research on inactivated vaccines of Gamma and Delta strains. Some units have submitted clinical trial application materials to the Drug Administration; some units are conducting preclinical research on bivalent vaccines; at the same time, broad-spectrum or multivalent recombinant protein vaccines for different mutant strains have been carried out, and some units have also submitted clinical trial application materials to the Drug Administration; they have carried out research and development of adenovirus vector vaccines and nucleic acid vaccines for beta strains and Delta strains. Some units have completed animal effectiveness and safety trials and are preparing to apply for clinical trials. Relevant institutions have preliminarily formulated guiding principles for the development and evaluation of mutant vaccines. Once a serious mutant strain appears, vaccines targeting the mutant strain can be put into production soon.
Head of the Vaccine R&D Special Team of the Scientific Research and Development Group of the State Council’s Joint Prevention and Control Mechanism: At present, it seems that for the Delta strain, the effect will be clear after our existing vaccination, especially after the strengthened vaccination is carried out. So we are prepared for the research on mutant viruses but do not use them for the time being, and it is not necessary to use them.
