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Pig Circovirus Disease is a viral infectious disease characterized by immunosuppression, and its clinical manifestations are relatively complex. The circovirus is seriously invasive to immune organs and can lead to a high degree of suppression of the body's immune system. Circoviruses can make vaccine immunity ineffective and reduce or disappear. Representative diseases of circovirus include pig post-weaning multisystem failure syndrome, dermatitis nephrotic syndrome , sow breeding disorders, respiratory diseases of weaned and fattened pigs, pig diarrhea syndrome and central system diseases in piglets. Therefore, once the pig ring type 2 virus is infected, pigs at different stages will show different clinical symptoms.
Because circovirus can destroy the immune system of the pig body, cause immunosuppression, and cause secondary immunodeficiency, this disease is often mixed with blue ear disease , parvovirus, pseudorabies, and pig para Haemophilus , asthma, pleuropneumonia, Pasteurella and Streptococcus .
2. Hazards of pig circovirus disease:
Hazards 1. Weaned piglets multisystem syndrome
1. Weaned piglets gradually lose weight or grow slowly. Other symptoms include anorexia, depression, slow movement, pale skin, messy hair, difficulty breathing, and respiratory disorders characterized by cough.
2, superficial lymph nodes are swollen, and swollen lymph nodes can sometimes be touched, especially the shallow inguinal lymph nodes; anemia and visual mucosa jaundice . All the above clinical symptoms may not be seen in a pig, but all the symptoms can be seen in the onset herd.
Hazards 2, Dermatitis and nephrotic syndrome
This disease usually occurs at 12-14 weeks of age. Sick pigs are manifested as anorexia, dullness, paleness, fever, conjunctivitis, difficulty breathing, diarrhea, and weight loss. Round or irregularly raised papules appear on the skin.
mainly harms growth and fattening pigs, with a mortality rate of 15% to 20%. It has been resistant to pig dysplasia and slow production. Adult pigs are generally hindered infections and do not show any symptoms or lesions, but their growth rate has significantly decreased.
Hazards 3. Pig Diarrhea Syndrome
Fattened pigs have unknown diarrhea that cannot be cured for a long time in many cases. Its clinical manifestations are alternating diarrhea and normal defecation, the effect of medication is not obvious, and repeated delays.
The cause is that circovirus damages intestinal tissue, intestinal tissue failure, intestinal wall atrophy, and chronic enteritis. This kind of enteritis is very difficult to treat.
Hazards 4. Symptoms of congenital tremor
Congenital tremor in piglets. Piglets tremble continuously after birth and often starve to death because they cannot eat milk. If care is strengthened and the piglets can eat colostrum, not cold or hungry, they will generally survive in a few weeks. Recovery at 3 weeks of age. Fattening pigs are paralyzed for unknown reasons. Fattening pigs suddenly have inflexible hind legs and are paralyzed.
Hazards 5, reproductive disorder
Swallows are manifested as miscarriage, stillbirth, increased mummy fetus, and increased pre-weaning mortality rate.
Hazards 6. mixed infection
1. Circular virus infection can cause immunosuppression in pigs, thus making the body more susceptible to other pathogens. This is also the reason why Circular viruses are related to mixed infections of many diseases in pigs.
2. The most common mixed infections include blue ear (PRRSV), PRV (pseudorabies virus), PPV (parativirus), Mycoplasma pneumoniae, polysaccharide Pasteurium , PEDV (epidemic diarrhea virus), and SIV (swine influenza virus). Some are double or triple infections, and the mortality rate of sick pigs will also be greatly improved, and some can reach 25% to 40%.
3. Key points of clinical diagnosis
1. It mainly occurs in pigs at 4 to 18 weeks of age, and they grow well before weaning.
2. Piglets in the same litter or different litters have respiratory symptoms, such as diarrhea, developmental delay, and weight loss. Sometimes pale or jaundice occurs. Antibiotic treatment is ineffective or poor.
3. Anthropologic examination shows that lymph nodes are enlarged, spleen womb, lung swelling, interstitial widening, and the surface is scattered in brown mutation areas of varying sizes.
6. Prevention and control plan:
Prevention: Piglets receive circular vaccines on 14 days, and can be exempted from two exemptions during 20 days, and sows can be exempted from general exemptions.
Treatment: Individual injection: Immediately isolate the onset pigs and suspected onset pigs and intramuscular injections of high-emission serum , and mix the injections with astragalus polysaccharide and ceftifu (5 mg per kilogram of body weight) intramuscular injections, once a day, for 3 consecutive days, and intramuscular injections with enrofloxacin on the other side;
