China Xiaokang Network, Tianjin, June 21 (Chen Sicheng) Today, the media warm-up interview session of the "6th World Intelligence Conference" was held in the central kitchen conference room of Tianjin Haihe Media Center. Zhu Yonghong, President of Tasly Holding Group, accepted online and offline interviews from many media outlets across the country at the conference, and shared Tasly’s experience in introducing digital technology innovation into the manufacturing of traditional Chinese medicines.
Zhu Yonghong said that traditional Chinese medicine is a great creation of the Chinese nation, embodying the vast wisdom of the Chinese people. It is also my country's national industry with the most independent intellectual property rights advantages. It has played an important role in the fight against major diseases such as COVID-19 and SARS. The world Health organizations also highly affirm the effectiveness and safety of traditional Chinese medicine. Tasly interprets the codes of traditional Chinese medicine with modern science, builds an intelligent manufacturing system for traditional Chinese medicine with "quality digitization" as the core, creates a new model for the research and development of new traditional Chinese medicines, and a new model for intelligent manufacturing of traditional Chinese medicine industrialization, and has established a system for intelligent extraction of traditional Chinese medicine, dropping pills and freeze-dried powder. The modern intelligent manufacturing system represented by injections has realized the digitization and intelligence of the entire process of traditional Chinese medicine production.
"National Key Laboratory of Key Technologies for Innovative Traditional Chinese Medicine" and "National and Local Joint Engineering Laboratory for Advanced Manufacturing Technology of Traditional Chinese Medicine" are national key laboratories built by Tasly. It is relying on the scientific and technological strength of these two laboratories that Tasly has completed It has deeply integrated digital technology and traditional Chinese medicine industry. Scientific researchers integrated modern science and technology such as pharmacological efficacy, genetic network, industrial Internet, and big data to explain the effectiveness and safety of traditional Chinese medicine, decipher the "theoretical black box" of traditional Chinese medicine for treating diseases, and analyze the "process of quality control of traditional Chinese medicine" "Black Box" cracked the code of modernization of traditional Chinese medicine. At the same time, digital technology is applied to the research and development, manufacturing and clinical services of traditional Chinese medicine, throughout the entire life cycle of medicines, and with quality digitalization as the core, a modern intelligent manufacturing system of traditional Chinese medicine with the characteristics of traditional Chinese medicine is built.
In view of the digital and intelligent research and development of traditional Chinese medicine, Tasly has been concentrating on building the Xingdou Cloud artificial intelligence big data platform with independent intellectual property rights since 2017, which has promoted the leapfrog development from traditional Chinese medicine to digital Chinese medicine research and development. At present, the Xingdou Cloud platform has successfully accumulated 60T of massive characteristic medical data resources, built a multi-dimensional database covering disease multi-omics, Chinese medicinal materials-components-targets, drug small molecules, etc., and built an AI disease network, biomedical knowledge map, drug focus, etc. Positioning and other analysis pipelines for more than 30 items. The digital analysis technology of traditional Chinese medicine quality of gene network-targets-pharmaceutical components has been continuously optimized to realize digital research on syndrome differentiation and treatment of traditional Chinese medicine, compatibility rules of traditional Chinese medicine, multi-component and multi-target action mechanism, clinical practice of traditional Chinese medicine and evidence-based medicine.
On the basis of process digital design and intelligent equipment research and development, in order to digitally control the production process, Tasly established a quality control model covering all key processes such as traditional Chinese medicine extraction and preparation, achieving model control of the entire production process, and developed a comprehensive Industrial big data collection platform for production processes. Taking the core product Compound Danshen Dropping Pills as an example, there are a total of 2,100 collection points in the entire process. The automatic collection rate and visualization rate of the entire production process have reached 95%. During the annual effective production cycle, the total number of collected data records has reached 210 million. It also conducts real-time analysis and monitoring of key process parameters through the big data platform, with an online analysis rate of over 93%. It achieves the integration of real-time collection, storage, analysis, and monitoring of data throughout the production process, laying the foundation for the factory's underlying industrial control and upper-level information management.
"In order to implement digital management of the entire industry chain, Tasly has developed a digital system covering the entire chain of medicinal materials, manufacturing, quality, warehousing, logistics, etc., based on the characteristics of a long traditional Chinese medicine industry chain, wide management scope, and high upstream and downstream correlations, using industrial The Internet has realized the interconnection of systems and formed a closed-loop management of the entire industry chain." Zhu Yonghong said.
From R&D (GLP), Chinese herbal medicine planting (GAP), extraction (GEP), production (GMP) to sales (GSP), Tasly has established a standardization system for the entire Chinese medicine industry chain; with "quality digitalization" as the core, it has established Established a modern intelligent manufacturing system for traditional Chinese medicine.Through intelligent manufacturing of the entire industry chain, technical methods and systems with the characteristics of traditional Chinese medicine have been built, industry solutions and exportable mechanisms have been formed, a traditional Chinese medicine industry cluster covering pills, granules, and injections has been created, and a traditional Chinese medicine industry has been established. A model of intelligent manufacturing.
At present, Tasly is promoting the linkage between industry, academia, research and application, and with the help of the State Key Laboratory of Key Technologies for Innovative Traditional Chinese Medicine, it is exploring the use of modern medicine, biotechnology, and systems biology methods to interpret traditional Chinese medicine, interpret traditional Chinese medicine theory, and support good traditional Chinese medicine theory. Systematically inherit and innovate, accelerate the "research" of key technologies, and strive to make traditional Chinese medicine realize the transformation from "exclusive language" to "modern language", from "modernization" to "digitalization", and resonate with the development of modern science and technology.
