ingredients, leveraging the efficacy of skin care products. In recent years, , ceramide, , ectoine, centella asiatica... these professional names have become well-known to the public under the trend of repairing and effective skin care. However,
is limited by development technical difficulties, and there are also a few powerful treasures that have become "a hidden gem in the ocean." For example, fibronectin (English Fibronectin, referred to as FN), a regenerative repair factor widely used in medical trauma, is also included in the "Catalogue of Used Cosmetic Raw Materials" released by the State Food and Drug Administration . In the cosmetics industry , it is also a functional raw material ingredient that enters the "system".
uses medical-grade ingredients to solve skin problems, which can be described as a dimension-reducing blow. Fibronectin is the "leader" in repair in the eyes of those cosmetic engineers who pursue real effects. It has excellent effects on repairing damaged barriers and can improve the skin's self-healing ability. It can accurately treat sensitive skin and medical beauty. brings significant improvement to postoperative wounds and is regarded as an alternative to EGF and an unparalleled savior of damaged muscles.
However, its activity is difficult to preserve in normal-temperature skin care products such as water, cream, and cream, which troubles engineers. Skin care products focusing on fibronectin on the market basically exist in the form of freeze-drying and binary sprays. Due to the high threshold of survival technology, fibronectin has not been widely used in the field of skin care products for many years, and it has missed its opportunity to shine.
However, uncompromising researchers are breaking this situation. Shanghai Fibronectin Biotechnology Co., Ltd., which obtained the world's first fibronectin biomedical new drug certificate and fully owns the independent intellectual property rights of FN's patented technology, and Guangzhou Ruisen Biotechnology Co., Ltd. took 3 years to break through FN's Dilemmas of active preservation in aqueous creams. The two companies have joined forces to leverage their respective advantages, unique technologies and raw material advantages, and complementary resources. Both parties are conducting in-depth application innovation of fibronectin in the field of skin care products, and have accumulated more than 200 intellectual property rights, 6 major scientific research results, With more than 90 invention patents, Ruisen Biotechnology, whose scientific research creates excellent quality, will provide one-stop repair solutions for brand owners.
Scientific research giants join forces
to awaken the powerful repair power of FN.
The history of development and innovation of fibronectin raw materials in China embodies the history of unremitting efforts of three generations of Shanghai Fiber Company to develop and apply FN:
In 1987, Professor Wang Deliang He and Professor Zhang Junying published China's first scientific research review paper on FN, and obtained China's first FN invention patent in 2006. They were the founders of the development and application of fibronectin in China.
Wang Bin, the son of two professors, is the chairman of Shanghai Fiber Company. Out of his mission to transform his parents’ scientific research results, he chose to establish a company without hesitation and devoted himself fully to the industrialization revolution of fibronectin, leading Shanghai Fiber Network. Lian is the world's first FN medical drug, establishing the medical value of FN.
arrived at the third generation of FN development and application in Shanghai Fianlian - Wang Bin's daughter Wang Haoqing. She resolutely gave up the opportunity to study at Oxford University and chose to return to China to support her father in further developing the FN cosmetics market.
She said, "In the domestic cosmetics market, fibronectin products are mixed. It is my sacred mission as the third generation of FN to allow domestic consumers to use authentic, safe and effective fibronectin."
Wang Haoqing's words Chairman Wang Meixian and his R&D team of Ruisen Biotech were deeply impressed. It is also the mission and goal of Ruisen people to break through the new heights of China's scientific and technological skin care with professional strength. Therefore, Ruisen Biotechnology decisively joined forces with Shanghai Xianlian to advance the breadth of FN applications and fill the gap in high-end FN products in China.
Dr. Nie Zhou, chief scientific research and technology officer of Ruisen, spent three years of intensive research, and after thousands of experimental challenges and repeated adjustments, finally found a breakthrough using Ruisen's exclusive PhatNm® particle patented technology, breaking through the FN survival barrier, relying on PhatNm® particle packaging Using Ruisen's unique formula system, Nie Bo successfully preserved the activity of fibronectin in normal-temperature water creams and essence cosmetics. In many stability experiments he conducted, FN maintained high activity without loss throughout the process, announcing The application prospects of FN have been opened up, and the repair product line has been extended in all directions, which will benefit hundreds of millions of consumers with sensitive skin, medical and aesthetics.Dr. Xie Shuilin, president of
Ruisen Research Institute, has also continued in-depth research and put the pure FN raw materials developed by Shanghai Fianlian into human body efficacy verification, testing its effectiveness, safety and rigorous experimental logic on different types of sensitive skin. , strict evaluation standards, effective data support, and great efforts in theory and practice. Xie Bo's scientific and rational efficacy evaluation test fully proves that fibronectin can perfectly replace the growth factor EGF that is not included in the list of cosmetic raw materials. In the post-EGF era, it brings new hope to the Chinese beauty industry and provides more ideal and effective repair for damaged skin.
Professor Lai Wei, chief consultant of Erruisen Research Institute, said that the continued research and development of fibronectin skin care products will build a solid competitive barrier for China's functional raw materials and enhance the confidence to compete with international brands. As a cosmetic review expert, it is gratifying to see that FN’s repair performance is so good in clinical practice. China’s raw materials and development and application technology will be recognized by consumers.
Based on the impressive results achieved by the two major companies in the early stage of cooperation, Shanghai FiberLink and Ruisen Biotech decided to jointly establish the "Fibronectin Development and Application Joint Innovation Laboratory" to further deepen the " industry-university-research " cooperation between the two parties and jointly promote FN The pace of industrialization in the field of cosmetics. Two high-end national enterprises simultaneously unveiled the joint laboratory in Guangzhou and Shanghai on July 15.
This means that FN is expected to usher in its era in the cosmetics industry after becoming popular in the medical circle. HP Volkswagen will benefit more people with sensitive and damaged skin and set off a new round of revolution in skin barrier repair.
Learn about fibronectin: a legendary skin barrier repair factor
Fibronectin is produced by the liver and vascular endothelial cells . It is widely present in animal tissues and tissue fluid . It is a macromolecular glycoprotein with cellular The biological function of regeneration and repair can speed up the repair efficiency of the skin, so it is often used in the medical field to treat burns , trauma and the healing of traumatic wounds.
It is not difficult to find that fibronectin and the growth factor "EGF" have similar regenerative repair effects, and both are often used in medical wound repair.
But when they enter the field of cosmetics, they have completely different treatments. EGF, which was once popular in the functional skin care market, has fallen out of favor since 2019. The reason is that the State Food and Drug Administration clearly stated that any act of adding or promoting EGF in cosmetics is illegal. The reason is that due to its large molecular weight, EGF is not available in normal products. It is difficult to be absorbed under skin barrier conditions. Once the skin barrier function is incomplete, other potential safety issues may arise.
Fibronectin is different. It is found in the human body itself and is very safe. It is a legal and compliant raw material registered in the "Announcement on the Name Catalog of Used Cosmetic Raw Materials" of the State Food and Drug Administration. Regeneration factor FN has many advantages as a cosmetic raw material: homologous to the skin, safe and mild, clear mechanism of action, etc.
Its achievements in skin barrier repair are particularly outstanding. As a matrix for the growth of cells and , it can accelerate cell migration, make cells have good morphological structure, enhance metabolic rate, accelerate cell growth, strengthen the stratum corneum, and has ceramide-like properties. Function, this is the key to repair redness of sensitive skin. It is like a shot in the arm for the redness and soothing process of sensitive skin. It can speed up the skin's restoration of healthy barrier and improve the skin's resistance to external stimulation such as sun exposure and makeup. Tolerance and continuous stabilization of skin condition.
As a component widely used in wound healing in regenerative medicine, fibronectin is particularly useful in "reducing dimensionality" and repairing wound skin after medical art. It can accelerate the growth of tissue and skin, shorten the healing time of damaged skin, and alleviate wounds. scar , prevent scabs and reduce the possibility of pigmentation scars.
Shanghai Fianlian
According to the "China Expert Consensus on Sensitive Skin Diagnosis and Treatment" report, about 36.1% of women in my country have sensitive skin problems, and there are more than 210 million people with sensitive skin. They urgently need a type of high-tech efficacy. Type ingredients can deeply solve problems such as redness, stinging, dryness, itching and burning, giving the skin a chance to "rebirth".
Fortunately, my country's "pioneer" in the development and application of fibronectin in cosmetics is here. Shanghai Fibronectin has teamed up with Ruisen Biotechnology. The two parties have combined several cutting-edge biotechnologies to overcome problems such as the stability of FN in normal temperature cosmetics. Today, the top R&D teams of two high-tech companies have reached an in-depth technical cooperation and jointly established a "Fibronectin Development and Application Joint Innovation Laboratory" to expand the application breadth of fibronectin, a high-energy repair ingredient, in cosmetics. to 1+, FN can also be seen in water, cream and cream from now on, providing more professional solutions for the vast number of people with sensitive skin in my country.
Amazing Chinese repair ingredients, amazing Chinese scientists, amazing Chinese scientific research technology. We have reason to believe that with the diligent exploration of scientific research masters, fibronectin will definitely achieve great results in the field of skin care and skin care, and become the protector of sensitive and damaged skin, post-medical and art repair, red bloodshot and other problematic skin. , becoming a shining star among ingredients.
