artificial insemination and IVF are currently widely used in assisted reproduction. With these two technologies, countless infertile families have realized their dreams of having children. However, these two methods of fertilization are not completely universal, the success rate of choosing a proper fertilization is twice the result with half the effort, and the wrong choice, the success rate is low or completely ineffective. In daily outpatient clinics, infertile couples are often blind when requesting fertility.
To make everyone better understand this problem, let me give you two examples first.
Case 1, Chen Moumou, 33 years old, endometriosis for more than 5 years, accompanied by chocolate cysts, pelvic adhesions, regular menstruation, and the man's semen routine examination was normal. Because I have not conceived for many years, artificial insemination is required. The doctor at
reproductive center told her that artificial insemination is not suitable for this situation. Because of endometriosis with chocolate cyst , pelvic adhesions are heavy, fallopian tube patency and morphology are often poor, artificial insemination is difficult to succeed.
Case 2, Zhu Mou, 29 years old, married for 3 years and not pregnant. Sexual life has been scarce in the past two years. He has been asexual for half a year. The man was diagnosed with ED (erectile dysfunction), and both parties decided to do IVF to solve the fertility problem. The doctor of the IVF Center reminded that in this case, IVF is not needed yet, but it is recommended that they use artificial insemination first. Because the main cause of their infertility is the problem of the male’s sexual function, artificial insemination should be the first choice to solve the problem that sperm cannot enter the female reproductive tract normally. Only when artificial insemination fails repeatedly or is accompanied by other infertility factors (such as severe Few, asthenospermia ), only consider IVF.
So, what are the principles and basis for infertility couples to master when choosing these two assisted reproductive technologies? Below, I will introduce them separately.
Artificial insemination (IUI) and its indications!
Intrauterine insemination is to inject the husband’s semen into the woman’s uterine cavity after washing, centrifugation, and optimization to achieve the purpose of assisting conception. In addition, very few cases require intracervical artificial insemination (ICI) and intravaginal artificial insemination (IVI), which will not be detailed here.
Artificial insemination is usually applicable to the following scope:
1, the man has mild or moderate oligospermia and asthenospermia.
2, semen liquefaction is not complete or not liquefaction.
3. The man’s erectile dysfunction or dyspareunia caused by psychological factors.
4. Infertility caused by immune factors (positive for anti-sperm antibody , anti-endometrial antibody, anti-phospholipid antibody, etc. in the woman’s blood).
5. Infertility caused by the woman’s cervical disease, such as cervical stenosis , upturned cervix, semen pool cannot pass the uterine orifice, severe cervical erosion, mucus plug blocking the cervical canal, etc.
6. Unexplained infertility (no clear infertility factor has been found after various examinations), artificial insemination can be tried first. The advantage of
artificial insemination is that it is relatively simple, economical, and can be performed in several consecutive cycles. Artificial insemination is mostly carried out in a natural cycle, which can avoid the stimulation of the ovaries caused by ovulation stimulating drugs . For couples who choose artificial insemination, in addition to the above indications, also needs some necessary basic conditions, such as:
1, the woman needs a smooth fallopian tube, at least one fallopian tube is unobstructed.
2. The woman should have natural ovulation function or have a dominant follicle formation after using a small amount of ovulation stimulating drugs.
3, only suitable for moderate and mild oligospermia and asthenospermia. If the sperm is too few and too weak, artificial insemination is often difficult to work.
Due to the inherent factors of this technology, the success rate of artificial insemination is low, about 10%-15%. When artificial insemination is unsuccessful many times, consider changing to IVF.
Test Tube Baby Technology (IVF-ET) and its applicability!
IVF refers to in vitro fertilization-embryo transfer. Simply put, the woman uses ovulation-stimulating drugs to grow and develop multiple follicles in a short period of time. After maturity, the eggs are collected by vaginal puncture under the guidance of ultrasound, while the man staysTake the semen, combine the sperm and egg in the laboratory to develop into an embryo, and then transfer the embryo into the uterine cavity.
IVF technology is suitable for infertility caused by the following reasons:
1, fallopian tube obstruction caused by various reasons, , patency, abnormal morphology or abnormal function.
2, endometriosis, pelvic adhesions caused by chronic pelvic inflammatory disease, , those who have failed laparoscopic treatment.
3, ovulation dysfunction, such as polycystic ovary syndrome, luteinized unruptured follicle syndrome, etc.
4, the man with moderate or severe oligoasthenospermia and teratospermia.
5, the man's obstructive azoospermia (testicular puncture with sperm).
6. Unexplained infertility, unsuccessful other treatments such as artificial insemination.
IVF is usually fast and has a relatively high success rate. The success rate of women of childbearing age can reach about 40-50%. Infertility factors that cannot be solved by artificial insemination and other fertility measures can be changed to IVF treatment. Of course, compared with artificial insemination, IVF is more expensive, longer cycle, and more complicated.
