Friends who take atorvastatin calcium want to know how the onset of this medicine is? , how about maintaining time? What to do if you miss the dose, what are the side effects of taking atorvastatin calcium, etc., this article is very important to you, please read it patiently.
First: The minimum dose of atorvastatin calcium is 10 mg per time, and the maximum dose is 80 mg per time, once a day.
absorbs quickly after taking the medicine, and the blood drug concentration reaches its peak for 1 to 2 hours; cholesterol starts to decline for 3 to 5 days, and the effect of maximum inhibition of cholesterol synthesis is achieved in about 2 weeks.
Half-life is 20 to 30 hours. After stopping the drug, the effect of inhibiting cholesterol synthesis can be maintained for several days. Food will not affect the absorption of this drug, so when you take the medicine, it is not limited by time, you can do it before and after meals, and you don’t have to worry about whether you take it during the day or at night. Just take it regularly for a fixed time every day. Of course, if you have some gastrointestinal reactions, it is recommended to eat after a meal.
Second, what should I do if I find that the medication is missed? If it is found within 12 hours, you can take the medicine as soon as possible and take the medicine at normal time the next day; if it has been more than 12 hours, you do not need to take the medicine as normal the next day; be sure to be careful not to take the dosage of at one time.
Third, the most common side effects of atorvastatin calcium may occur with myalgia, diarrhea, nausea and increased aminotransferase, which may also cause increased blood sugar. Therefore, if you take atorvastatin calcium for a long time, you should pay attention to regular amino acid search. If it has exceeded and , you should stop the medication. If it has occurred muscle pain, check the creatine kinase in time. If it exceeds 10 times the normal value, you should stop the medication. You should also pay attention to regular blood sugar check.
Fourth, atorvastatin calcium is the metabolism of P4503A4 of liver enzymes. Some drugs can cause an increase in plasma concentration of atorvastatin, increasing the probability of side effects. The most common ones are clarithromycin, cyclosporine, and itraconazole . Try to avoid taking it with the above drugs or adjusting the dosage of atorvastatin calcium. Do you know?
Pharmacy Popular science, for reference only
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