coronary heart disease is mostly caused by qi deficiency and blood stasis , qi stagnation and blood stasis, or qi and yin deficiency, resulting in insufficient qi and blood throughout the body. coronary artery cannot provide blood and oxygen to cardiomyocytes, which eventually leads to cardiomyocytes and leads to cardiomyocytes with degradation, and a series of clinical symptoms appear. The fundamental treatment is to invigorate qi and promote blood circulation, nourish yin, promote qi and open orifices, promote blood circulation and remove blood stasis, , unblock the meridians and relieve pain, etc. In clinical practice, Yuxinkuang Capsules , Musk Heartburnin Tablets , Tongmai Yangxin Pills , etc. are commonly used.
Yuxinkuo Capsule
Yuxinkuo Capsule, consisting of Red Ginseng , Panax notoginseng , and Yanhusuo . It has the effects of invigorating qi and promoting blood circulation, unblocking meridians and relieving pain. For patients with angina pectoris with qi deficiency and blood stasis syndrome, the symptoms include chest tingling or colic, pain, chest tightness and shortness of breath, fatigue, etc. In the formula, red ginseng greatly replenishes vital energy to consolidate the foundation, strengthens the qi to promote blood circulation, removes blood stasis without damaging the body; Panax notoginseng promotes blood stasis, removes blood stasis and produces new blood; prolongs Hu Suo and unblocks the meridians and relieves pain. The three medicines are used in combination, taking into account both the symptoms and the root causes, and taking both the attack and supplements, complement each other.
Modern pharmacological studies have shown that red ginseng, Panax notoginseng, Yanhusuo, etc. have obvious effects on dilating the coronary artery, reducing the resistance of coronary artery , relieving vasospasm, increasing coronary blood flow, and improving microcirculation. In addition, red ginseng also has a cardiac-strengthening effect, which can increase the content of ribose and nucleic acid in myocardial glycogen , improve the anabolic of ischemic myocardial, and thus provide a material basis for ischemic myocardial. The pharmacological effects of red ginseng, Panax notoginseng and Yanhulu are well targeted to the pathological basis of coronary heart disease.
clinical observations show that this drug can reduce blood viscosity, inhibit the adhesion of platelets , reduce the erythrocyte aggregation index , increase the deformation ability of erythrocyte , thereby comprehensively improving hematologic abnormalities and improving myocardial oxygen supply. It can reduce the degree and range of myocardial ischemia in the anterior descending coronary artery, reduce the area of myocardial infarction, and increase coronary blood flow. It has a good therapeutic effect on angina pectoris, can reduce the number of angina attacks or duration of attacks in patients, and also has a good effect on ST-T changes in electrocardiogram.
Musk Heartburnin Tablets
Musk Heartburnin Tablets, consisting of Yanhusuo (roasted with vinegar), artificial musk, Suhexiang , Chuanxiong , ginseng, borneol . It has the effects of promoting qi and opening orifices, promoting blood circulation and removing blood stasis, unblocking meridians and relieving pain. It is used for chest pain, , chest tightness, , swelling and pain in both flanks, shortness of breath, and palpitations, .
This medicine is a new Chinese medicine for treating chest aphthorax (angina pectoris) caused by qi stagnation and blood stasis syndrome. It embodies the principle of "treat the symptoms when the emergency is, and treat the root cause when the slowness is." In the formula, Yanhusuo is pungent and warm, and has the effect of promoting blood circulation, promoting qi and relieving pain. "Material herbal medicine seeks the truth" says: "If you take this force, whether it is blood or qi, it can be unblocked. If you take this force, it can be unblocked. Because of its warm nature, it can be unblocked and smooth, and if it tastes pungent, it can moisten and disperse it. Therefore, it can be used to regulate all pains in the body."
Chuanxiong is pungent and warm, and it can flow without guarding. It goes up to the top of the top, reaches the sea of blood, and opens up the middle to stagnate, which is a Chinese qi medicine for blood removal, promoting qi and relieving pain. It is a combination of qi and qi, promoting qi and relieving pain. It is a slight artificial musk fragrance to open orifices to open meridians and relieve pain. This group of prescriptions conform to the theory of traditional Chinese medicine. They select and select the medicines to be refined and in line with the pathogenesis, and have the functions of promoting qi and opening orifices, promoting blood circulation and removing blood stasis, and unblocking meridians and relieving pain.
Modern pharmacological research shows that Musk Heartburnin Tablets can reduce myocardial oxygen consumption by reducing the heart afterload, reducing myocardial contraction performance, and myocardial consumption of oxygen index (ventricular work and myocardial tone time index), improve the balance of supply and demand of myocardial ischemia, have a protective effect on ischemic myocardial myocardial, and reduce the range of infarction. At the same time, it can reduce blood viscosity, improve blood circulation, prevent thrombosis, and play a role in the treatment of angina pectoris in coronary heart disease.
Tongmai Yangxin Pills
Tongmai Yangxin Pills are a Chinese patent medicine preparation developed based on the classic prescription "Zhilihualian Tang". It consists of Rehmannia , Chicken Blood Vine , Ophiopogon japonicus, Polygonum multiflorum, donkey-hide gelatin , Schisandra chinensis, licorice , Codonopsis pilosula, vinegar thorn shell, cinnamon twig , and jujube. It has the effects of nourishing qi and nourishing yin, unblocking the meridians and relieves pain. It is used for angina pectoris of coronary heart disease and arrhythmia . The symptoms include chest pain, chest tightness, palpitations, shortness of breath, and pulse dysfunction.
prescriptions are used to nourish yin and blood, and are the main medicine; Ophiopogon japonicus clears the heart and moistens the lungs, licorice nourishes the middle and nourishes qi, Codonopsis pilosula nourishes the spleen and nourishes qi, and are the ministerial medicine; Dried jujube warms, nourishes the spleen and nourishes blood, donkey-hide gelatin nourishes the kidney and nourishes blood, and Polygonum multiflorum fills the essence and marrow, Schisandra chinensis acid dry and reinvigorates yin, nourishes kidney and yin, and is the lung qi, vinegar 1 nourishes blood and calms the nerves, and is the adjuvant medicine; cinnamon twigs are pungent and warms the yang, and the chicken blood vine replenishes blood and promotes blood, and is the same medicine; the whole prescription is to nourish qi and nourish yin, promotes blood and removes blood stasis, and relieves pain.
Modern pharmacological research shows that Tongmai Yangxin Pills can effectively enhance myocardial contractility, improve myocardial diastolic function, reduce blood viscosity, inhibit platelet aggregation, thereby dilating the coronary artery, increasing coronary artery blood flow, and protecting vascular endothelial function. Tongmai Yangxin Pills are used to treat angina pectoris, which can effectively reduce the frequency of angina pectoris, shorten the duration of angina pectoris, and improve the overall clinical efficiency. It can also increase the content of superoxide dismutase , malonaldehyde and ejection fraction , indicating that Tongmai Yangxin Pills can remove oxygen free radicals and dilate coronary arteries, thereby improving myocardial hypertrophy.
clinical studies show that Tongmai Yangxin Pills can promote the production of vascular endothelial growth factor and nitric oxide (NO) and improve vascular endothelial function. Vascular endothelial growth factor and NO are secreted by vascular endothelial cells , which can regulate vascular tone and permeability. Vascular endothelial growth factor can promote angiogenesis of in myocardial , improve ischemic myocardial reperfusion, promote the formation of collateral circulation, and thus relieve angina pectoris. NO is an important diastolic factor for vascular secretion. It can inhibit platelet activation, adhesion and aggregation, and fight vascular constriction substances such as endothelin-1; it can also inhibit oxidation of low-density lipoprotein, reduce oxygen free radicals, and reduce abnormal proliferation of vascular smooth muscle cells, thereby delaying the progress of atherosclerosis.
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