First, let's take a look at a few sets of basic concepts. What are the differences between tumors, cancers, sarcomas, etc.? A tumor is an abnormal tissue mass that grows uncoordinated with normal tissue and exceeds normal tissue, even if carcinogenic factors No longer exists, but

First, let's take a look at a few basic concepts. What are the differences between tumors, cancers, sarcomas, , etc.?

Tumor is an abnormal tissue mass that grows uncoordinated with normal tissue and exceeds normal tissue. It can continue to grow even if the cancer-causing factors no longer exist. Tumors are generally divided into two categories: benign and malignant. Malignant tumors are collectively called cancer. A key feature of cancer is the loss of normal regulatory mechanisms that govern cell survival, proliferation and differentiation, resulting in unregulated cell division and growth. Cancer is mainly divided into three categories according to the type of tissue origin, namely cancer (originating from epithelial tissue), sarcoma (originating from connective tissue , mesenchymal tissue ), leukemia (originating from blood), The first two types are called solid tumors and .

As the human body grows from the early embryo to the adult stage, embryonic stem cells regulate and regulate the division and differentiation of the cell cycle, eventually forming differentiated cells and losing their ability to divide. While certain cells called adult stem cells and are latent in various tissues, committed stem cells can be activated to divide in response to the body's needs. These adult-committed stem cells provide cellular supply and repair for physiological functions. Under carcinogenic conditions, for example, carcinogens induce stem cell gene mutations, causing stem cells to enter the cell division cycle unregulated, which can lead to cancer.

It can be seen from the above that malignant tumors originate from cells with the ability to divide and differentiate, and the heart is composed of cardiomyocytes. Cardiomyocytes are non-regenerable cells and do not have the function of division and differentiation, so they will not become cancerous. In addition, the blood flow rate in the heart is too fast, and cancer cells cannot colonize in the heart.

References:

1, Oncology, Jiang Guoliang, Du Xiang, Fudan University Press, 2005

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