Mr. Liu is a math teacher, he is 34 years old this year. Although the teacher can't make much money in this job, he lives a relatively comfortable life.
Some time ago, when he woke up in the morning, he felt obvious pain in his throat, and it was also more obvious when he swallowed. In desperation, he went to the clinic for treatment. After arriving at the clinic, the doctor diagnosed acute tonsillitis , and prescribed a little cephalosporin for Mr. Liu, and told him not to drink alcohol recently. After returning home, Mr. Liu kept in mind the doctor's instructions.
In the past two days, Teacher Liu’s good friend has returned from another place and insisted on treating him to drink. There was no choice but to bite the bullet and drink. However, drinking was a good time. After about 20 minutes, Teacher Liu suddenly developed symptoms of fatigue, headache, dizziness, and blurred vision. When my friend saw that the situation was wrong, he quickly sent Mr. Liu to the hospital.
After Mr. Liu arrived at the hospital, the doctor asked about the situation and initially considered the disulfiram reaction. After listening to the doctor's statement, Mr. Liu's friend looked confused and confused. Because of the timely treatment, Mr. Liu was eventually out of danger.
In real life, many friends know that they cannot drink alcohol during cephalosporin. In fact, in addition to cephalosporin, there are 6 other drugs that cannot be mixed with alcohol. In order to let everyone have more understanding and understanding of it, today the doctor will have a good idea to talk to you about the relevant knowledge.
1.What changes will happen after the wine is drunk?
When a person drinks, it enters the esophagus through the mouth, and then into the stomach and intestines. When alcohol passes through the mucous membrane, it may also enter the blood. Since alcohol has a certain excitatory effect on the brain, it may be exciting in the short term.
Although the amount of alcohol consumed increases, the heartbeat of a person will also increase accordingly, and due to the increase in heat production, some people will secrete more sweat.
Our digestive tract secretes a lot of digestive juices under the stimulation of alcohol. The secretion of digestive juices can help digestion. However, if the digestive juice is secreted too much, it may make the abdomen feel uncomfortable, and the digestive juice may be refluxed.
The alcohol that is drunk will be excreted from the body through the respiratory tract and sweat, and most of the alcohol will enter the liver for metabolism. There are three main steps in the liver to decompose alcohol, namely alcohol → acetaldehyde → acetic acid → carbon dioxide and water.
If the liver wants to metabolize alcohol, it needs the catalysis of relevant enzymes, such as ethanol dehydrogenase , acetaldehyde dehydrogenase , etc. If the human body lacks acetaldehyde dehydrogenase, the amount of acetaldehyde in the body will increase. Acetaldehyde itself dilates capillaries, which in turn causes symptoms of blushing. If too much acetaldehyde accumulates in the body, it may lead to alcohol poisoning, which in turn induces symptoms such as nausea, vomiting, headache, etc.
2. Why do you say cephalosporin just drink and leave when you say it?
Many friends may hear that eating cephalosporins will cause death, and they all say that they are unreliable. In fact, this statement is not without scientific reason.
Drinking alcohol during cephalosporin will easily cause disulfiram reaction. The disulfiram reaction was first discovered in 1948. People with disulfiram reactions will have symptoms such as flushing, headache, abdominal pain, nausea, palpitations, palpitations, and difficulty breathing.
Maybe you don’t understand what the essence of disulfiram is, so I will explain it here. Through the above introduction, I think you should be able to see that alcohol will undergo some changes after entering the human body, and the disulfiram reaction is mainly because a lot of acetaldehyde accumulates in the bodies of this type of people, which eventually leads to acute acetaldehyde poisoning.
When a person takes cephalosporin while drinking, cephalosporin will inhibit the activity of acetaldehyde dehydrogenase. The main function of acetaldehyde dehydrogenase is to decompose acetaldehyde. If its activity is inhibited, a lot of acetaldehyde will accumulate in the human body. Therefore, relatively speaking, eating cephalosporin during drinking is more likely to have disulfiram reactions.
Speaking of this, a friend may say, how long will it take for me to drink after taking cephalosporin? For most people, it takes 4 to 5 days to restore normal acetaldehyde dehydrogenase inhibited by cephalosporin. For safety reasons, you should drink alcohol after 7 days after taking cephalosporin. Some people cannot take cephalosporin in the short term after drinking. If you take cephalosporin, it is best to have a spacing of 4 days or more.
Certain sedative hypnosis drugs, such as phenobarbital, halidine, lemianning , etc. After being taken by people, this type of drug will affect the activity of liver drug enzymes and thus increase the concentration of drugs in the blood.
If the concentration of sedative hypnosis drugs in the blood increases, its inhibitory effect on nervous system will be enhanced, so it can cause symptoms such as drowsiness and coma.
❸ antipyretic analgesics:
Some antipyretic analgesics we usually take, such as aspirin, paracetamol , ibuprofen , etc. This type of drug itself has a considerable damage to the gastric mucosa. If you drink some alcohol while taking these medicines, it may damage the gastric mucosa, which will lead to gastric ulcers, , stomach bleeding, and even gastric perforation.
For most antihypertensive drugs, they are mainly metabolized in the liver. If you drink alcohol while taking antihypertensive medication, it may damage the liver.
At the same time, drinking itself may affect the efficacy of antihypertensive drugs, so blood pressure may not meet the standards. In the long run, drinking itself increases the risk of arteriosclerosis, which in itself is not conducive to blood pressure control. #Health 2022#
