Tail gland hyperplasia is generally only observed in the back of the tail. The area and local hair are seborrheic and scabs can be seen on the skin surface. Local hair removal, roughening and loss of luster, and hyperpigmentation were observed, which was caused by excessive seborrheic substances covering the skin. As dust, dander, etc. stick to the seborrheic area, dark, dirty patches have attracted people's attention.
In addition, it seems that an increase in sexual desire and aggressive behavior can be observed in cats with caudal hyperplasia.
It is reported that clinical symptoms may lead to suspicion of the disease, but some diagnoses were made histopathologically. In this case, no samples were taken for histopathological examination, so he could only be initially diagnosed with tail gland hyperplasia through medical history and physical examination.
According to relevant human diseases reports, androgens have an effect on the hair follicles and sebaceous glands on the skin, and can lead to the formation of seborrheic glands and the increase of secretions. Previous studies in humans reported that androgens are the cause of acne . After treatment, androgen levels declined and attention was paid to hormone disorders associated with the disease.
According to previous reports, tail gland hyperplasia in uncastrated male cats will be more severe, while tail gland hyperplasia in female and castrated male cats will be only mild or moderate. In several other studies, an increase in androgen levels may be associated with caudal hyperplasia. Conversely, the occasional occurrence of this disease in castrated males and females means that the relationship between caudal hyperplasia and hormone balance has not been resolved. The role of breed susceptibility in disease formation is not known, although it has been reported that the disease is common in adult cats. It is certain that the disease is an important issue for male animals and develops severely during and after mating season.
To sum up, tail gland hyperplasia is more important in cats. It often occurs during and after the mating season in adult males, and the development of the disease may be associated with an increase in testosterone. Due to limited reports on the disease of cats, we will need some more detailed, large, controlled studies to reveal the causes and hormonal links of the disease.