vaccination can "destroy" cancer cells. Do you believe it?
Recently, the co-founder of the German biotech company BioNTech said in an interview with BBC that the cancer vaccine based on based on mRNA may be released by 2030.
It will take more than ten years before the vaccine is launched. What is the difficulty in developing cancer vaccines? Is there really a cancer vaccine?
1. A man tried medicine with his body. Can cancer vaccines really eliminate cancer cells?
Cancer has always been one of the diseases that humans cannot overcome. The development history of cancer vaccines is even more tragic. It has been difficult for decades. Only one product is launched in the United States and is still unpopular after it is launched. It is very sad.
Tom Marcia is a cancer scientist, and he is also a cancer patient who has been fighting cancer all his life. In 1999, Marcia's mother was diagnosed with advanced pancreatic cancer and later died unfortunately.
After experiencing the death of his mother, Marcia made up her mind to develop a drug that could treat cancer. After hard work, Zykadia, a cancer drug that Malaysia participated in the research, made a major breakthrough.
But unfortunately, Marcia was also diagnosed with stage 3 colon cancer.
Macia knew very well that the tumor in her body would explode sooner or later, but before the outbreak, he still had a chance to fight.
So, after the diagnosis, Marcia quickly adjusted her lifestyle. He put on running shoes, ran 6 miles a day to enhance his immunity, and also shared his treatment experience with other colon cancer patients.
During the battle with colon cancer, unfortunate news came again, and Marcia was found to have melanoma again, so he lost the opportunity for clinical trials.
Macia did not give up, has won the opportunity to participate in the clinical trial of personalized vaccines . Unfortunately, due to the worsening of his condition, he failed to participate in clinical trials and died in 2017 after he died ineffectively.
2. Is the cancer vaccine going to be released before 2030? Is it reliable?
Many people ask: What does an ideal cancer vaccine look like? An ideal cancer vaccine needs to meet the following conditions: eliminate tumors and eradicate residues as much as possible, establish lasting anti-tumor memory, and avoid non-specific or adverse reactions.
As the largest biotech company in Europe, BioNTech has been studying mRNA cancer vaccines before the outbreak of COVID-19 .
Although after the global outbreak of the new crown epidemic, BioNTech will shift its focus to the development of the new crown vaccine , and successfully developed the new crown vaccine with Pfizer , , but it also promoted the progress of cancer vaccine research and development work .
Just a while ago, Moderna and Msodone jointly announced a cooperation in the development of cancer vaccines.
Currently, the cancer vaccine is being evaluated in combination with Merck's anti-PD-1 therapy KEYTRUDA as an adjuvant treatment for patients with high-risk melanoma in Moderna's ongoing Phase 2 clinical trial.
And at present, the cancer vaccine being developed by companies such as BioNTech and Moderna is a therapeutic vaccine. After receiving the cancer vaccine, the body's immune system can be activated and attack tumor cells.
However, unlike the common vaccine to prevent diseases, the therapeutic cancer vaccine of only plays a therapeutic role and can prevent tumor recurrence .
Although judging from the current situation, the development of cancer vaccines is still very difficult, and major difficulties need to be overcome, such as the effect of protecting immune systems may be weak and the lethality of tumors may not be strong enough.
However, it is of great significance to prevent recurrence after surgical radiotherapy and chemotherapy.
3. 2 vaccines that can prevent cancer, have you been given it?
Although the cancer vaccine has not yet been determined, the hepatitis B vaccine, HPV vaccine, and other vaccines can indirectly prevent cancer. Vaccination should be given in time to reduce risks.
- hepatitis B vaccine
hepatitis B is closely related to liver cancer . Liver cancer is a step-by-step chronic disease process and will go through trilogies: hepatitis B → cirrhosis → liver cancer.
That is to say, if hepatitis B is not effectively controlled, hepatitis B virus will continue to replicate in stem cells . In order to resist the hepatitis B virus, the liver will produce some fibrous tissue hyperplasia, leading to liver fibrosis, that is, cirrhosis. The further development of cirrhosis will lead to liver cancer.
So is there any way to prevent hepatitis B? vaccination with hepatitis B vaccine is the best method .
After receiving the hepatitis B vaccine, the body will produce effective hepatitis B surface antibodies to reduce or avoid hepatitis B infection. However, it should be noted that as time goes by, the protection of hepatitis B surface antibodies will also decrease.
reminds everyone that when vaccinating hepatitis B vaccine, you should pay attention to the following two points:
, the vaccination targets of hepatitis B vaccine
mainly includes newborns, infants, unimmunized people under the age of 15, as well as high-risk groups such as medical staff, organ transplants, and people with low immunity.
is not suitable for pregnant women, people who are allergic to hepatitis B vaccine components, people who are allergic to and have constitution , people who are infected with hepatitis B virus, patients with venereal diseases, patients with severe chronic diseases, etc.
. Regular tests for high-risk groups
For high-risk groups, regular tests should be carried out. If abnormalities are found, it is recommended to receive one dose of hepatitis B vaccine. For children and adults with normal immune function, routine antibody testing is not necessary.
- HPV vaccine
HPV is human papillomavirus , which is closely related to the occurrence of cervical cancer , anal cancer, vulva cancer and some skin diseases. HPV vaccine is a vaccine that can prevent cervical cancer, also known as cervical cancer vaccine .
clinical research results show that and HPV vaccine prevent precancerous lesions are close to 100% . After receiving the HPV vaccine, the protection obtained can last for at least 8-10 years, and there is currently no evidence that the protection will disappear.
Currently, HPV vaccines have three types: bivalent, tetravalent and nine-valent. The main difference is that the types and quantities of vaccine prevent viruses are different. The higher the price, the more types and quantities of viruses that can be prevented.
Generally speaking, my country's bivalent HPV vaccine is suitable for women aged 9-45 years old, quadrivalent HPV vaccine is suitable for women aged 20-45 years old, and nine-valent HPV vaccine is suitable for women aged 9-45 years old.
So, no matter what vaccine it is, it will be effective in reducing the risk of disease to a certain extent. Although cancer vaccines have not been developed yet, we still have to take relevant vaccines that can indirectly reduce cancer risk.
Reference
[1] "Cancer vaccine is not reliable? In fact, this is a history of struggle that has repeatedly failed.》Guoke. 2021-07-21
[2] "Technology Frontiers丨Cancer vaccine may be released before 2030? 》. Sichuan Anti-Cancer Association.2022-10-18
[3] "After getting hepatitis B vaccine = won't you get hepatitis B? Please keep this vaccination guide! 》. Medical Digestive Liver Disease Channel.2022-09-16
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