It has been more than two years since the outbreak of the new crown epidemic in 2020. Moreover, the COVID-19 pandemic is not over now, and there are still many confirmed cases in the world every day. This pandemic has had a huge impact on the world, and it has triggered a severe social and economic recession (this recession is the largest global recession since the Great Depression). So when will the COVID-19 pandemic end? It has become a voice of everyone. Anand, known as an Indian prodigy, has brought a prophecy to everyone about when the pandemic will end.
Anand's prediction video screenshot on June 30
Indian prodigy Anand's prediction
Indian prodigy Anand predicted in a video on June 30 that although the problem of the epidemic still exists so far, the epidemic problem after 2023 will not be a problem that bothers people. Here you can know that Anand predicts that the epidemic problem will be solved after 2023 and will no longer become a problem that troubles people. Although everyone hopes that the sooner the pandemic will end, the better, the facts may not be ideal. Because the new coronavirus is still mutating, from the original primitive strain to the delta and then to the current omickron and its sub-variants, the virus mutation seems to have not stopped.
Why does the virus mutate
There is no gene mutation, and there may be no world we are familiar with now. These tiny errors can occur randomly at each time the cell or the virus itself, providing raw materials for evolution. Mutations can mutate in the population, which allows natural selection to amplify features that help the creature thrive—showing the long neck of a giraffe onto tall leaves, or caterpillars disguised like feces to escape bird attention.
However, in a pandemic, the word "mutation" appears ominous. Although viruses are not technically alive, they can mutate and evolve when they infect host cells and replicate. The resulting tweak to the genetic code of virus can help it spread between humans more easily or escape the defense of the immune system. Viruses evolve and obtain mutations are something that happens naturally, and when people get infected, the virus replicates itself by hijacking people’s cells and attempts to spread to others. But not every copy is perfect. Sometimes the virus goes wrong, and the genome of the new copy looks slightly different from the original one. In fact, the vast majority of these mutations either do not alter the way the virus behaves (null mutations) or have a negative impact on the virus’s ability to replicate or infect the host (harmful mutations).
Most importantly, these mutations occur randomly, but the speed of their occurrence depends on the virus. The enzyme that replicates DNA viruses, called DNA polymerase , can proofread and repair genetic errors generated, leaving few mutations in each generation of copies. However, RNA virus , such as SARS-CoV-2, RNA polymerase , which replicates viral genes, usually lacks proofreading skills, which makes RNA virus prone to high mutation rates (about one million times higher than the host DNA-containing cells). As time goes by, the number of people spreading the virus continues to increase, and the chances of giving it mutation are also increasing.
It is very difficult to completely eliminate the new coronavirus
The only human disease we humans eliminate is smallpox, but the host of smallpox is very single. Moreover, the degree of mutation of smallpox virus is incomparable to some RNA viruses. In contrast, the current new coronavirus has not a single host. It is a zoonotic disease (an infectious disease that spreads from animals to humans or from humans to animals) between species. Zoonosis is World Health Organization (WHO) The Zoonotic Expert Committee defined in 1951 as “diseases and infections that are naturally transmitted between vertebrates and humans, 75% of new human diseases are zoonotic. Some zoonotic diseases also include AIDS , avian influenza or rabies , which can be very dangerous to humans and can lead to death.
Zoonosis is increasingly linked to environmental changes and human behavior.Logging, mining, road construction in remote areas, rapid urbanization and population growth have led to the destruction of virgin forests, which has given people closer contact with animal species that may have never been exposed to before. There is evidence that the reduction of biodiversity can have an impact on host diversity and the frequency of human-animal interactions and may lead to pathogen spillover.
Global climate change will also increase the risk of disease pandemics! is now . The extent of global warming is increasing, and it has a direct impact on human health. Climate change also affects the growing season and pollen because the number, sensitization and spatial distribution of pollen increases as the growth season begins or durations increases. Climate change affects vector-borne diseases by affecting the survival, distribution and behavior of vectors such as mosquitoes, ticks and rodents. Viruses, bacteria and protozoa are carried by these vectors and transferred from one vector to another.
vectors and pathogens can adapt to climate fluctuations by changing and expanding their geographical scope, which can alter the incidence of new cases based on vector-host interactions, host immunity and pathogen evolution. This means that climate change affects infectious diseases by affecting the length and geographical extent of the seasons that are spreading infectious diseases. Vector-borne diseases are a concern because they play an important role in human history and determine the rise and fall of civilizations. This is why the World Health Organization believes that climate change is one of the greatest threats to human health.
In short, the new coronavirus is not only a zoonotic disease, but its continuous mutations also increase uncertainty in the future. Finally, I hope the COVID-19 pandemic will end soon. The above is what we have today. I am Huo Zongjun, see you next time.
