Mother's Day is approaching, what should I buy gifts is a trouble for many filial children. Recently, advertisements have been urging "smeared glucosamine ", saying that they are "not strong enough". As expected, I have recently received some friends asking if "smeared glucosamine" is effective for knee pain caused by degenerative arthritis? Especially for a certain "XX Pass-through Care Soothing Cream", many people believe it because they think the spokesperson is a professional medical staff. Today, please see our compilation of relevant literature and evidence to let everyone understand how much these operators can believe!
What is glucosamine? Why is glucosamine so hot?
Why is glucosamine so red? It is mainly because glucosamine is one of the important substances in the formation of "arthritis". Chinese people have a long history of "replenishing what you eat". If glucosamine is an important substance for forming joint cartilage, then eating a little more should give you more cartilage, right? This idea is very intuitive, but it may not necessarily be like this when the body actually works.
You may think that glucosamine is glucosamine, is there anything wrong with it? Of course there are, and there are three types. Let's first distinguish the type of glucosamine.
There are three common glucosamine types:
sulfate glucosamine sulfate
hydrochloride glucosamine (glucosamine hydrochloride)
N- acetyl glucosamine (N-acetyl-glucosamine, NAG)
Many studies believe that the "sulfate" type of glucosamine is more likely to be effective. The sulfate type of glucosamine is regarded as a drug to manage. Currently, there are only oral dosage forms to relieve the pain of degenerative arthritis, and have not been made into topical dosage forms. Other types of glucosamine are so far considered "food" to manage, which means that the types other than glucosamine sulfate, whether eaten or rubbed, only need to be safe and not harm the body. It does not need to prove that it is effective, but it cannot be claimed to be effective by law. Is glucosamine rubbed by
effective?
Recently, more and more health products are called "graft glucosamine", emphasizing convenience, small molecules, and easy to absorb, but is this really the case? We searched for a long time and only found a relatively relevant clinical study. Although the experimental results pointed out that the glucosamine ointment has a more obvious pain relief effect than the placebo, other things were actually added to the ointment, such as chondroitin, camphor, and peppermint oil. I was stunned when I saw this. If you want to do an experiment, shouldn’t you reduce the interference factors?
For example, if you want to prove whether you are allergic to chocolate, and you don’t eat pure chocolate, but you bought a mint vanilla mustard lavender curry flavor chocolate, even if the final result is allergic, but how do you know if you are allergic to chocolate or the bunch of mint vanilla mustard lavender?
So although the results of this experiment seem to be effective, it is impossible to know whether it is the effect of glucosamine or the effect of other ingredients. And this is an experiment from more than ten years ago, and there has been no relevant research since then. Usually, when the effect is achieved, the manufacturer will quickly further prove that this ingredient is effective and you can make a fortune next. But this experiment has not been continued for the next ten years. What is going on? Let it be for you to see. Generally speaking, normal inferences are afraid that a glucosamine experiment will be done simply, and the result will be slap yourself in the face or be seriously questioned.
Sometimes you will see manufacturers emphasize "exclusive technology small molecule NAG" and "skin is easy to absorb." Some people may ask, is the small molecule lipophilic glucosamine (NAG) effective? It is indeed easier to absorb glucosamine into NAG types, but where does NAG go after absorption? It is currently believed that it may be related to reducing skin pigmentation, but there are no relevant research on pain relief. So if you focus on products that are more "effective" in NAG, you should basically have doubts about it.
Is glucosamine what helps you relieve pain? Or other ingredients in the cream?
If you look carefully at the full ingredients of the related products, you will find that in recent years, the creams that focus on "glucosamine" are actually "not only" one ingredient of glucosamine, but also have many substances that are considered to be able to relieve pain, such as camphor, capsaicin, etc. So the question is the same as in the previous article. There is no way to determine what is playing a role.
This method is similar to many skin care products that focus on magical whitening effects. If you are selling a whitening product that contains evidence-based whitening ingredients such as vitamin C, then of course you will have a chance to whiten it, but you can only sell it cheaper. At this time, if you think about whether we have added precious "XX protein" or "XX peptide", it can be very expensive, but whether the whitening effect comes from vitamin C or these so-called proteins or peptides can only be guessed.
summarizes the conclusion: According to the current data, the evidence related to pain relief by applying glucosamine is very limited, and almost all glucosamine creams contain other ingredients, which are often found in general pain relief ointments. If you want to relieve pain, just buy cheap and evidenced pain relief ointment. Don’t think that you can really rely on this "grabbed" small molecule glucosamine to "maintenance" or even "relieve pain".
"XX Pass-through Nursing Soothing Cream" Skill
After reading these, let's crack the relevant Skills.
on the purchase page of similar products, it clearly implies that the patient can use "soothing" and "maintenance" locally if the patient is in pain.
If they really made small molecule glucosamine that could really relieve pain, the whole world would have been rushing to buy patents.
This time the team doctors and pharmacists sorted out the relevant data together. We asked three questions directly: The small molecule glucosamine that is advertised as easy to absorb, but do you know that paper is talking about "pigmentation" and isn't it about pain?
Is there any way to relieve pain in small molecule glucosamine? If not, why hint in the ad?
Could you please ask where your small molecule glucosamine is absorbed? Subcutaneous or blood circulation?
dare not say it explicitly in the advertisement, probably because he is afraid of being fined. However, after reading the entire advertisement, he also recommends "after exercise" or "local use". People without relevant professions can easily be induced to think that using "graft glucosamine" can relieve pain.
knowledge is for sharing, not for plundering. If you want to be a famous person and talk nonsense, please do not wear that "experimental clothing" every time to pretend to be a white robe or a professional. Professional medical personnel must come out to condemn such behavior.
Today, in addition to slapping the face, we are more important to make scientific, logical and empirical research to let everyone clearly understand what the "small molecule glucosamine" is. Please spend a few minutes reading this article together and share it with all your friends, don’t be fooled by such fake professionals and advertisements. "Maintenance is science, not rituals." Only by establishing correct knowledge can you not spend money all the time to worry about your heart or even spend money to harm your body.
