"Chinese Guide" special report group
Japan's vaccination number has increased day by day, but ominous events have also occurred frequently.
According to data from the Ministry of Health, Labor and Welfare, the total number of deaths after vaccination in Japan has reached 1,093, and more than 1,000 people. It is unknown whether there is a causal relationship with vaccination. The United States produced Moderna vaccine mixed with foreign bodies and died after injection of related vaccines, but the causal relationship is also unknown; 80% of the 39 infected people in the Saitama Prefecture elderly facilities have been vaccinated twice, which has questioned the effectiveness of the vaccine.
On the other hand, the Japanese government claims to have prepared 220 million doses of Pfizer and Moderna vaccines, which is enough for each citizen to receive twice, but now it is extremely difficult to make a vaccination appointment, and even a long queue is required to select. Japanese archipelago is causing a wave of "vaccine panic".
Foreign objects are mixed with the Moderna vaccine
Two people were killed in the relevant vaccine
Japan's Ministry of Health, Labor and Welfare said on August 26 that due to reports from multiple vaccination centers that foreign objects were found in the unused Moderna vaccine, the Japanese government decided to suspend the use of 1.63 million doses of Moderna vaccine.
Japanese broadcaster NHK uses the Ministry of Health, Labor and Welfare as the source of the news that since August 16, 8 large-scale COVID-19 vaccination centers located in Tokyo, Saitama Prefecture, Ibaraki Prefecture, Aichi Prefecture and Gifu Prefecture have been found in 39 unused Moderna vaccine bottles, and the foreign objects found are granular.
House Affairs Bureau found 4 vaccine bottles with foreign objects mixed in, indicating that "visual confirmation was conducted, and there was a black object less than 1 mm in the bottle." At the venue in Ibaraki Prefecture, the pharmacist found black and brown particles mixed in before the injection, and at the venue in Saitama Prefecture, there was a black sediment. A cadre from the provincial government said that foreign objects may be metal sheets.
Ministry of Health, Labor and Welfare received a report from Takeda Company on the 25th on the 25th on the vaccine, and decided to suspend the use of 1.63 million doses of Moderna vaccine from the 26th. The vaccines came from the same production line at a Spanish factory, involving 3 batches, and have been distributed to 863 vaccination sites in Japan. The media said that of the 1.63 million doses of vaccine, the batches of problematic vaccines were located in total. However, for caution, two batches of vaccines similar to this batch have also been suspended.
On February 22, 2021, at the Tokyo Disaster Hospital, an independent administrative law worker health and safety agency, Yamamoto, Deputy Minister of the Ministry of Health and Labor, inspected the prevention and vaccination of the new coronavirus infection. Source: Ministry of Health, Labor and Welfare web page.
Moderna vaccine was developed by the American pharmaceutical company Moderna, and its sales in Japan were handled by the Japanese pharmaceutical company Takeda Pharmaceutical Industry Company. Takeda said it is entrusting Moderna to launch an emergency investigation and it is not yet possible to determine what the foreign object is. The vaccination certificate contains information such as the date of vaccine production, place of origin and batch number. The vaccinated person can check whether there may be problems with the vaccine he has vaccinated.
Japanese government data shows that since the Moderna vaccine obtained emergency use authorization in Japan in May, it has received more than 10 million doses of people aged 12 and above. The Japanese government has signed a contract with Moderna to receive 50 million doses of vaccines by the end of September.
The Tokyo Metropolitan Government announced that the vaccine used in large vaccination sites and professional vaccination sites in Tokyo is the same as the vaccine batch number of mixed foreign bodies. The vaccine may be contaminated by foreign bodies, and the number of vaccinated people is about 9,100.
According to the Tokyo Metropolitan Government, at the Nogizaka venue in Minami Aoyama, Minatoi, the batch numbers of all vaccines delivered are the same. From the 18th to the 25th of this month, about 2,800 people were vaccinated. In addition, since the 17th of this month, about 6,300 people have received the same batch of vaccines at the vaccination site in the Tokyo Metropolitan Government Building.
In addition, the same batch number of vaccines were also sent to the venue of the Tokyo Metropolitan South Observatory, but because they are still in a frozen state, they are not used.
It is said that the Tokyo Metropolitan Government directly contacted the vaccinator through email and other means, and guided them to the Du Consulting Center for consultation, but it has not yet been confirmed whether there are health victims.
was found in the Nogizaka venue on the 20th and 22nd in three bottles of vaccines, but it was not used for vaccination, and was taken back by vaccine supplier Takeda Pharmaceuticals.
Tokyo Metropolitan Government will stop using the remaining 30,000 vaccines that have not been used yet.
In view of the news released by the Ministry of Labor and Labor in the early morning of the 26th, the Department of Culture suspended workplace vaccination targeting people related to culture and art. The all-Japanese air transportation company said it will stop vaccination at Tokyo Haneda Airport on August 26 and 27. Japan Airlines canceled the vaccination of some employees, and Tokyo Metro also canceled the vaccination on the 26th. Okinawa Prefecture suspended the vaccination at the prefecture wide-area vaccination center that day.
43% of Japan's population has completed two doses of vaccination cycles, but cases are increasing due to the spread of the delta variant virus . In other parts of Asia, only Singapore , Bhutan and Maldives were vaccinated at higher rates, with 76%, 63% and 55% of the population receiving two doses, respectively.
January 27, 2021 at Kanagawa Prefecture Kawasaki City Care Short-term University for hearing about vaccine injections. Photo source: Ministry of Health, Labor and Welfare web page.
According to AERAdot on the 27th, Hiroyuki Moriuchi, a professor at Nagasaki University who serves as the director of the Japanese Vaccine Society, pointed out: "Although it is not a novel coronavirus vaccine, foreign matter is occasionally mixed in previous vaccines."
According to Professor Moriuchi, there have been cases of mixed plastic and rubber fragments in vaccines in Japan and overseas in the past. About 10 years ago, there was a case in Japan where a mixture of nylon-like chemicals and glass fibers were incorporated into the "Hib vaccine" that prevents infant infectious diseases.
Professor Morinaga pointed out: "Because of these situations in the past, the instructions for the vaccine also said, 'You need to check visually.' Maybe a foreign object was found before vaccination. Since the injection is made in a sterile environment, there is no need to worry about germs. Moreover, the injection needle of this new crown vaccine is very thin, and foreign objects are not easy to enter. Even if it is in, it is very small, so it can be inferred that there is almost no impact on the human body.
. According to Kyodo News on August 29, Japan's Ministry of Health, Labor and Welfare released a news report on August 28 that two men in their 30s who died after receiving the new crown vaccine were vaccinated with the vaccine from Moderna, the United States, which was produced in the same factory and became the target of suspension of use. No foreign body was found in the vaccine used in the use of the vaccine, and the causal relationship between the vaccination and death is unknown.
is responsible Takeda Pharmaceutical Industry, which is sold and distributed in Japan, announced on the same day that it would investigate whether there is a causal relationship. The deaths were men aged 38 and 30, who had no history of underlying diseases and allergies, and died after completing two vaccinations.
, President of the Ministry of Health and Labor Special Investigation Association and Nagaoka Akira, Saitama Prefectural Children's Medical Center Hospital, pointed out that "it is necessary to discuss it by experts" on the causal relationship. He said that for products with foreign bodies, "it is necessary to pay careful attention to reports of suspected adverse reactions." He said that "it is necessary to pay attention to reports of suspected adverse reactions when mixed with foreign bodies. He said that "it is necessary to pay attention to reports of suspected adverse reactions with causality." ”.
The cumulative number of people who died after receiving the new crown vaccine in Japan has exceeded 1,000. So far, no cases of experts assessing and determining that vaccination is causal and related to death.
According to the Ministry of Labor and Labor, it was previously announced that the discontinued vaccine was delivered to 863 vaccination venues, but the results after detailed inspection were 889. The province also disclosed on its homepage that the venue has been confirmed to be used.
On January 27, 2021, Yamamoto's Deputy Minister of Health, Labor and Workers, who were inspected on vaccine injections at the Tokyo Medical Center, an independent administrative legal person, institution. Photo source: Ministry of Health, Labor and Welfare web page.
The prevention effect of the new crown vaccine was questioned
htmlOn August 26, 1,709 confirmed cases of novel coronavirus infection in Saitama Prefecture, and 5 men and women in their 40s and 80s died. The infection after two vaccinations is also obvious.
Among the 1,709 people found on the 26th, 40 men and women in their 30s and 90s have received the vaccine twice.
In addition, there are 6 men and women in their 50s and 90s who are staff and residents of the county's elderly facilities. The total number of infected people at the facility is 39, with about 80% of whom have completed two vaccinations.
The county’s infectious disease control department said, “In an environment where people are close to each other, such as at home or in facilities, the delta strain is highly contagious enough to get infected even if vaccinated.”
Tochigi Prefecture and Utsunomiya City, Japan announced on August 7 that 164 new people were infected with the novel coronavirus. There are 9,216 infected people in the county. 28 residents, including elderly people in an elderly facility in , Sakura City, were confirmed to be infected, and their age ranged from their 70s to their 90s. The county government identified it as a mass infection.
occupants in these elderly facilities have been vaccinated twice. According to the county government, as of the 7th, a total of 31 people were infected at the facility, with 28 elderly people staying in the facility and three staff members in the facility. All 68 elderly people living in the facility have completed the second vaccination, and except for the 28 infected, the other 40 were negative. If
28 out of 68 people were infected, the infection rate of the vaccine after two vaccination would be quite high, as high as 41%.
The vaccines currently used in Japan are mainly Pfizer and Moderna, and recently, the AstraZeneca has been added.
Various data reactions, the Pfizer vaccine is 95% effective in preventing COVID-19 infection, while Moderna is about 94.1%. However, the validity period is usually only about half a year, and the antibodies will continue to decline after that.
5 htmlOn May 24, the Prime Minister of Suka Yoshihide Hika inspected Self-Defense Force Tokyo Massive Vaccination Center. Source: Prime Minister’s Residence Webpage.
According to Reuters , a study conducted by the authoritative American medical institution Mayo Clinic on more than 50,000 coronavirus patients showed that the effectiveness of Moderna's vaccine to prevent coronavirus was 86% at the beginning of this year. By July, when the epidemic became mainstream with the Delta strain, it dropped to 76%; the effectiveness of the Pfizer vaccine dropped from 76% to 42%. The high reinfection rate after vaccination in the elderly facilities in Sakura City, Japan may also be related to the Delta strain.
According to a study on the effectiveness of the new crown Pfizer vaccine, three months after the first vaccination, the amount of virus antibodies dropped to about one-quarter of the time after two vaccinations.
located in Toyoaki City, Aichi Prefecture, Fujita Medical University investigated the antibody content of 209 faculty and staff who received the Pfizer vaccine twice. The results showed that 3 months after the first vaccination, the antibodies decreased by about 1/4 compared with those 2 weeks after the second vaccination.
On the other hand, Professor Yohei, who conducted the investigation, predicted that two vaccinations can suppress the risk of worsening of the disease for a long time. Even if the antibody drops to about 1/4, the prevention effect will exceed 1/4.
The US Centers for Disease Control and Prevention (DCD) pointed out that although the COVID-19 vaccine works well, some COVID-19 full doses of vaccinated people will still get sick because no vaccine will be 100% effective. This situation is called a vaccine breakthrough case. However, the data suggest that immunization can make symptoms less severe in people who are still infected with COVID-19 after immunization.The mRNA COVID-19 vaccine has been shown to provide critical illness and hospitalization protection for all ages who meet vaccination conditions, including those at high risk for severe COVID-19 disease age 65 and older. After immunization, the human body usually needs about 2 weeks to establish protection. Two weeks after receiving the second dose of Pfizer-Biotech or Moderna vaccine or receiving a single dose of Johnson & J&J/Janssen vaccine, you will become a full-dose immunizer. Shortly after immunization, you may still be infected with COVID-19 because your body does not have enough time to establish protection. Keep taking preventive measures before you get full dose immunization.
Japan vaccination is still in short supply
With the opening of the 2020 Tokyo Paralympic Games , the world once again set its sights on Tokyo, Japan, which insists on holding large-scale events under the rapid spread of the new crown epidemic. Faced with the fierce mutant virus, a large number of foreign sports people entering the country and the high number of infections every day, Tokyo urgently took two measures in August to protect the health of the people:
one was to open the first oxygen station for new crown patients on August 23, providing auxiliary treatment for mild patients who cannot find the hospital to receive oxygen;
one was to open the first unavailable vaccination center for young people on August 27, which can save reservations and waiting time and quickly help young people with surges in infections complete vaccination.
On August 27, Tokyo opened a non-appointment vaccination center specially set up for young people in the Qurei Labor Welfare Hall in Shibuya District. Given that young people are currently a high incidence of infection, and all districts in the capital are in a state of extreme tension in vaccine appointments, this vaccination venue is specially opened for young people aged 16 to 39, which can be directly vaccinated on site without reservation.
The newly established vaccination center is planned to be open for six days a week from August 27 to October 8 except Monday. In principle, vaccination will be conducted from 12 noon to 8 pm every day (the final acceptance time is 7:30 pm). The vaccine used is the Pfizer vaccine in the United States, and about 200 people are scheduled to be vaccinated every day. As long as people aged 16 to 39 who live or work or school in Tokyo, they can receive the Pfizer vaccine on site with the vaccination voucher and identity documents received from the district office on the same day. The identity certificate includes driver's license, personal number card, health insurance certificate, passport, student ID, etc. After vaccination, you can make an appointment for the second vaccination on the spot, which is very convenient.
However, there is a shortage of supply in Shibuya and other places. Tokyo has expanded the scope of vaccination to three venues: Prospect room venues and Nogizaka venues on the south and north of the Tokyo Metropolitan Government Building to promote vaccination for young people.
The third shot of the new crown vaccine
Since data shows that Delta variant virus has become stronger in its ability to break through the existing vaccine protection, the debate over whether it should be vaccinated and whether it is necessary to get the third shot (enhanced shot). The answer to the question of whether
should be vaccinated is actually yes.
According to the comprehensive opinions of relevant authoritative persons and vaccine manufacturers, no vaccine can prevent viral infection by 100%. The situation of being infected after being vaccinated is medically called a "breakthrough case." Breakthrough cases is normal, not an exception. Although the protection rate of the US Pfizer vaccine for the Delta variant virus has dropped from 76% in the early stage to 42%, and the effectiveness of the Moderna vaccine has dropped from 86% to 76%, according to previous studies, the effectiveness of the Pfizer vaccine to avoid severe illness and hospitalization after infection with the Delta variant strain is still 93%. So even if Delta virus is coming in full force, vaccination is still the only way to effectively resist the invasion of viral invasion and cause serious illness.
Next, let’s talk about the third needle, which is what everyone calls the enhancement needle.
In the public eye, the earliest information about the third shot should come from an elderly male from Hokkaido, Japan. It is reported that he received four doses of the US Pfizer COVID-19 vaccine between April and July. The reason is that he believes that a few more vaccinations can "improve immunity."
Not long after, the discussion on the official launch of the third dose of the new crown vaccine worldwide has gradually been raised by some countries with a high vaccination rate.
Among them, the country that took the lead in the third dose of inoculation was Israel. According to reports, Israeli President Herzog, 61, became the first person to inoculate the shot on July 30, and vaccination for ordinary people began on August 1.
htmlOn August 22, the Israeli Ministry of Health released data showing that after people aged 60 and above received the Pfizer COVID-19 vaccine, the protection effect was significantly better than after receiving two doses of the vaccine. Reuters quoted data and reported that compared with the overall protection effect after 10 days of receiving two doses of vaccine, the overall protection effect of people aged 60 and above in Israel after 10 days of vaccination with enhanced injections is 4 times higher; in terms of preventing and treating severe cases and hospitalized cases, the effect is 5 to 6 times better.
Israel's experience has prompted many countries to provide enhanced vaccine injections to the people.
According to the information we have, at least the United States and France have begun to vaccinate the third shot. The United States plans to provide booster shots for the new crown vaccine to all American adults starting September 20. France will be injected with the third dose of the new crown vaccine from September 1 to strengthen protection, and the third dose of the vaccine will be extended to those over 65 years old and high-risk groups. It is estimated that a total of 18 million people in France will receive the third dose.
Japan also considered the third shot inoculation. Minister for the promotion of COVID-19 vaccination in Japan Taro Kono said on August 19 that "in order for medical staff who are responsible for COVID-19 treatment to carry out additional vaccination, relevant preparations are being promoted."
However, there are still disagreements in the vaccination of the third dose, and some main arguments focus on it having no scientific basis. More out of the mentality of "being in case of external ones".
WHO senior official said at a previous press conference that there is no sufficient evidence to prove that the third dose of the new crown vaccine is needed.
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British researchers found that the protection effect provided by vaccinating two doses of Pfizer and AstraZeneca began to weaken after 6 months, but it does not mean that the vaccine is ineffective. In fact, the vaccine can still provide efficient protection, including immune protection against the Delta strain.
WHO Director-General Tedros Adhanom Adhanom Adhanom from the perspective of reducing global vaccine inequality, he said that he was "very disappointed" with the uneven distribution of vaccines worldwide. Vaccine stocks in wealthy countries are increasing, while many countries can only provide the first and second doses of vaccines to some of the population. In response, Tedros called on countries that are preparing to receive enhanced shots to share vaccines with other countries to increase coverage of their first and second doses.
