The following is the exciting content of this conference: "2022 Annual Conference": The first day's wonderful review | Wonderful photo gallery | The Great Leap Forward of Technology | Perchoa on the New Long March | Li Yuanhong | He Wangxiao | Sanmu | Dong Junzi | Day and Dawn |

2025/05/0308:59:37 fashion 1689

From the perspective of dermatologists, JF Labb Skin Research's efficacy skin care is based on solving patient problems.

Source | Jumei

Author | Xiaolizi

At present, new brands are conducting research on effective skin care products from different aspects. Some brands use biotechnology to innovate raw materials, or develop new raw materials from natural plants, some brands change and improve formula design, or innovate in transportation and packaging technologies.

And JF Labb Skin Research's research and development perspective is different from most brands. uses the perspective of a dermatologist and follows the logic of "hospital-laboratory-market" to "make products", and develops skin care products from the perspective of solving the skin problems faced by patients. has embarked on a new path of effective skin care.

At the Jumei domestic new product forum not long ago, JF Labb's Vitamin A collagen essence was selected as "2022 Awesome domestic new product".

Jumei domestic new product forum site

JF Labb founder Dr. Jeff has worked in the University of California Affiliated Hospital and the Second Affiliated Hospital of Harvard University, serving as dermatologist and director of acne respectively. Jeff is currently working at the first Affiliated Hospital of Zhejiang University, , and serves as a research expert in dermatology.

Jeff has 10 years of clinical experience in dermatology. The research and development team of the brand also includes three doctors from Harvard . starts from the patient's skin problems and develops products based on scientific research and clinical experience.

At the site of the new domestic product, JF Labb brand head, Carolina Wang, Carolina Wang, took Viagra collagen essence as an example to share "the efficacy of skin care in the eyes of dermatologists."

"Being Doing" Advantages of Product Research and Development

Currently, most brands follow the "market-lab-hospital" logic when developing products. Starting from the market, conduct market research, analyze market trends, and understand popular ingredients; the brands then cooperate with scientific research institutions or laboratories to develop raw materials and design formulas; finally perform efficacy verification in the hospital. The path of

can be considered a classic model of "making products" based on the market insights and insights into consumer demand. However, as dermatologists such as Dr. Jeff have joined their own brands, the model of "making products" based on their technical background has also begun to impact the Chinese cosmetics industry.

For example, when JF Labb was developing products, it was based on the logic of "mainly making products" in "hospital-laboratory-market". After a large number of treatments, dermatologists will find common problems in the patient's skin; when solving the problem, they find that there is no suitable product on the market; therefore, they enter the laboratory for ingredients to be prepared and solve the problem in a targeted manner; if the patient has good feedback after using the laboratory formula, they will eventually launch the formula on the market.

"Hospital-laboratory-market" R&D logic has certain advantages, which is reflected in the following three aspects (analyzed with product vitamin A collagen essence as an example):

1 Based on a large number of cases, it is clear about the generality and particularity of patient problems

dermatologists have rich clinical experience and have treated a large number of patients. Based on these experiences and cases, they can better summarize the current common skin problems and the special points of the problems. When Jeff was a dermatologist at California , like local doctors, based on the skin types of people of different races, they usually prescribe tazarotine with 0.1% retinoic acid , and whites with ointment containing 0.025% retinoic acid. For Asian yellow people, adapalin with 0.1% retinoic acid.

Black, white, and Asian people have different skin types and different tolerance to retinoin

However, according to the feedback from Chinese patients on adapalin, Jeff found that Chinese people generally have symptoms of adapalin intolerance. Since dermatologists abroad can customize the formula, Jeff began to think: for all Chinese people, how should the formula for retinoids be done to avoid intolerance.

2 iterative formula can be used clinically and continuously adjusted to achieve the optimal efficacy

brands developed by traditional logic often only conduct clinical efficacy verification in the hospital's dermatology department before the product is about to be launched.Dermatologists will use it clinically during every iteration of the product formula, adjust it according to the patient's feedback, and finally develop skin care products with the best efficacy.

In 2010, Jeff's colleague Nancy shared a research result with him: the efficacy of vitamin A derivatives is basically the same as that of Retinoic Acid (also known as retinoic acid, which has the effects of removing acne, fading fine lines, and fading spots).

Based on this research result, Jeff developed the first customized vitamin A and its derivative formula suitable for Asians in 2015, adding vitamin A (retinol), vitamin A palmitate (retinyl Palmitate), and vitamin A acetate (retinyl Acetate).

After this formula was put into clinical use, the patient's feedback was less than that of adapalin, but the overall mildness was still lacking.

When working at Harvard in 2017, Jeff was exposed to HPR (Hydroxypinacolone Retinoate), a molecule with good clinical data, so he replaced vitamin A acetate in the formula with HPR and improved the ingredient concentration.

HPR molecular structural formula

This modified formula has received better feedback in clinical use, but when the formula goes from hospital to market, there is no guidance from doctors, it is necessary to consider whether the concentration of consumers when using it is still consistent with the guidance of doctors. Therefore, Jeff continued to adjust to this issue in the next two years.

According to reports, during the seven years of research and development, based on clinical use, 100 formula adjustments have been made, and the efficacy and gentleness have been continuously optimized, and finally a more tolerant, more comprehensive and more targeted Asians have been developed.

3 Classify the case manifestation problem, and then refine it and solve it targetedly

Dermatologists classify the problems shown based on a large number of patient cases, clarify the causes of this problem through surface symptoms, and solve it targetedly from the root.

Jeff and colleagues statistically classified the adverse reactions of Asians to retinoic acid, and finally divided them into three situations, and solved them one by one:

The method of validation of efficacy is more scientific and

The method of validation of efficacy of dermatologists is more scientific, mainly manifested in:

1 Selecting ingredients supported by a large number of papers and clinical data

Some brands will consider some new ingredients when selecting ingredients. The new ingredients have certain innovative value, but they are controversial. The number of clinical test data or related papers will be relatively weak, the number of some ingredient papers is less than 5, and the human body efficacy test may be less than 100 cases.

. Dermatologists prefer ingredients to have a large number of papers and clinical experimental data to support ingredients. For example, there are 742 clinical research papers related to vitamin A and skin. Its efficacy is clear, which is equivalent to improving or appropriate formula design on the shoulders of giants, which is more scientific and convincing.

2 Blind testing for various formulas to verify

's efficacy verification When the tester does not know the specific formula, let the tester give the most fair and truest feedback in terms of efficacy, skin feeling, fragrance, etc. This method is rarely used by brands in the efficacy verification of skin care products.

Jeff is a dermatologist and a skin care blogger. Several product formulas finally determined during the development of JF Labb were blindly tested among 2,000 fans, and the best formula was selected for the market.

Dimensional A Collagen Essence Efficacy Verification

has undergone multi-dimensional efficacy verification. This vitamin A Collagen Essence has a ratio of intolerance in clinical experiments <0.1%,>

is based on the professional perspective of dermatologists. The first product of JF Labb brand launched this year, Viagra Collagen Essence, its link-type anti-aging essence, collagen promotion, antioxidant and anti-sugar, and it won praise as soon as it was released.

JF Labb Vita A Collagen Essence

Different Skin Care concepts

From the perspective of a dermatologist, it is more rational and objective to look at the skin care process and skin care products.

Jeff believes that the purpose of medical methods and the use of skin care products are the same - improving the skin condition, and is a long process. When Jeff solves the acne problem for patients, each patient has at least three interviews, and the dosage and solution are not the same as the solution.

So one product cannot solve all problems in the entire process, and one product cannot solve all problems of all consumers. When choosing skin care products, consumers should also choose the skin care products they need based on their own situation.

In addition, compared with the more popular skin care concept of "morning C and late A" on the market, Jeff advocates the concept of "BCA": If the skin barrier of the stratum corneum is damaged, first use vitamin B to treat it; after the skin barrier is repaired, then consider using vitamin C to solve the acne and other problems in the epidermis; finally, use vitamin A to solve the problem of collagen loss in the dermis.

In order to better spread the scientific skin care concept to the public, Jeff is a dermatologist and also a Douyin celebrity named "Harvard No. 1-Dr. Jeff".

on Douyin , Jeff has about 810,000 fans and has released 205 videos, conveying scientific skin care methods to people through short videos, such as how to remove acne marks and how to quickly brighten the skin tone. The maximum number of likes in skin care videos reaches 230,000.

Dr.Jeff TikTok account

It is understood that in addition to Vitamin A collagen essence, JF Labb has currently launched Niacinamide three-dimensional essence, Vitamin C morning gloss essence, Vitamin C collagen ampoule and other products.

Dermatologist Jeff and his team use objective skin care concepts and based on the R&D logic of "hospital-lab-market", adopt scientific efficacy verification methods to develop skin care products for patients to solve skin problems. These advantages are also the reason why JF Labb's skin research's Viagra Collagen Essence was selected as a new domestic product in Jumeirah. In the future, JF Labb will continue to bring consumers better skin care products.

Related link: Dr.Jeff: Former Harvard dermatologist, how do you view the research and development of skin care products?

From "Global New Product" to "Houlang Special" , has been updated in in nearly 200 issues in in 34 years, Jumei is continuing to pay attention to the development of new brands.

On August 17 this year, the 2022 Jumei Conference "Amazing New Domestic Products" branch venue showed off the representatives of excellent beauty products that Jumei believes are worthy of attention. This article is one of the series of reports on the brands on the list.

▷ Wonderful review:

Visual design: Lele

WeChat typeface: Gaogao

Editor: @Summer Children's Shoes

—— “Endless Frontier” Industry Conference——

The 2022 Jumei Conference, sponsored by “Baizhicui”, came to an end in Hangzhou. The theme of this conference is “Endless Frontier”. Jumei believes that the next stage of brand competition will be based on the upgrading of R&D technology-driven products and marketing. The following is the exciting content of this conference:

"Awesome New Domestic Products": Talk about the Future of Chinese Products | 13 New Product Cases (Part 1) (Part 2) |

fashion

Everyone has their own unique label, but when it comes to the unique representative female stars in the entertainment industry, it is Liu Yifei. After all, her title as the "fairy sister" is not for nothing. Her temperament is basically unique. So I always feel that Liu Yifei's a

The most bold outfit of "Sister Fairy" is to wear "Polka dot translucent" as clothes, attracting attention

05/03 1553

For the south, the temperature difference is not obvious. You don’t need to consider the issue of keeping warm when wearing it. In fact, this also adds more possibilities for girls to match. This year, a way of wearing is popular called "short front and long back". Such items hav

This fall, a way of wearing is popular, called "short front and long back", which is high-end and fashionable

05/03 1134

Everyone knows that women's skirts are rich, so rich that they don't repetitively when changing clothes for 365 days a year. However, modern women seem to prefer skirt dresses when choosing skirts. Compared with traditional dresses, skirt styles are also rich, and in terms of fas

Carina Lau took her mother to see the sea in Busan and couldn't see Tony Leung. She wore a jacket and skirt, and her mother and daughter's facial features were like pancakes.

05/03 2000