Seborrheic dermatitis(SD) is a chronic, relapsing inflammatory skin disease. Symptoms are characterized as follows: on the basis of erythema , it is often accompanied by desquamation and itching . Predisposing areas are: scalp, face, chest, back, armpits and groin area.
Seborrheic dermatitis is incurable, and treatment focuses on removing signs of the disease; improving associated symptoms; and maintaining remission with long-term treatment. Treatment methods are mainly three aspects: anti-inflammatory, anti-fungal and anti-keratin .
1. Treatment of scalp seborrheic dermatitis
The scalp is inconvenient to use ointment because of the hair. Of course, if you have a bald head, you can enjoy more abundant treatment methods. For details, please refer to the body part seborrheic dermatitis introduced later. treat. The treatment of scalp seborrheic dermatitis is based on various lotions.
, 2%ketoconazole lotion
Mechanism of action: antifungal, inhibits Malassezia cell wall synthesis.
Usage: As a shampoo, it should be left on the hair for 5-10 minutes before rinsing; use it at least 2-3 times a week or every day. It may take several weeks to see visible results.
Side effects : rare, less than 1% of patients have contact dermatitis, which is manifested as a certain degree of itching and burning; about 3% of patients have dry hair and scalp, if it occurs, you can use conditioner .
, 2.5% selenium disulfide lotion
Mechanism of action: anti-keratin, also has a certain anti-fungal effect.
Usage: Same as Ketoconazole Lotion.
Side effects: Contact dermatitis occurs in about 3% of patients.
Seborrheic dermatitis(SD) is a chronic, relapsing inflammatory skin disease. Symptoms are characterized as follows: on the basis of erythema , it is often accompanied by desquamation and itching . Predisposing areas are: scalp, face, chest, back, armpits and groin area.
Seborrheic dermatitis is incurable, and treatment focuses on removing signs of the disease; improving associated symptoms; and maintaining remission with long-term treatment. Treatment methods are mainly three aspects: anti-inflammatory, anti-fungal and anti-keratin .
1. Treatment of scalp seborrheic dermatitis
The scalp is inconvenient to use ointment because of the hair. Of course, if you have a bald head, you can enjoy more abundant treatment methods. For details, please refer to the body part seborrheic dermatitis introduced later. treat. The treatment of scalp seborrheic dermatitis is based on various lotions.
Mechanism of action: antifungal, inhibits Malassezia cell wall synthesis.
Usage: As a shampoo, it should be left on the hair for 5-10 minutes before rinsing; use it at least 2-3 times a week or every day. It may take several weeks to see visible results.
Side effects : rare, less than 1% of patients have contact dermatitis, which is manifested as a certain degree of itching and burning; about 3% of patients have dry hair and scalp, if it occurs, you can use conditioner .
Mechanism of action: anti-keratin,At the same time has a certain antifungal effect.
Usage: Same as Ketoconazole Lotion.
Side effects: Contact dermatitis occurs in about 3% of patients. Some degree of scalp staining may occur.
Other lotions that have a certain effect include: 1% zinc pyrithione, 4% coal tar, 1.5% ciclopirox amine, etc. Among them, may be the most effective ketoconazole lotion , but the effect of the same lotion may decrease after long-term use. You can replace every month and use alternately to maintain the effect. When the treatment effect is good, gradually reduce the frequency of lotion use and maintain the improvement.
For more severe scalp seborrheic dermatitis , you can use compound lotion , such as Kangwang which contains both ketoconazole and glucocorticoid .
or more effective alone with topical corticosteroids, such as Hasinide solution , apply to the most severe part of the local rash, twice a day, stop after symptoms are relieved.
Note that hormones should not be used for too long. In addition, if the scalp scabs are thick, you can use salicylic acid lotion on the basis of the above treatment to soften the scalp and increase the curative effect.
Second, the treatment of facial seborrheic dermatitis
is common in cheeks, nose, eyebrows parts, manifested as desquamation based on erythema , may be accompanied by itching .
Common treatment methods include:
Mechanism of action: Powerful anti-inflammatory.
usage: 2 times a day, for the affected area, generally no more than 1-2 weeks of continuous use.
side effects: long-term use can cause skin atrophy , telangiectasia, folliculitis, hirsutism and hypopigmentation.
commonly used is pimecrolimus cream or tacrolimus ointment .
Mechanism of action: Inhibits the production of cytokines by T lymphocytes , thereby playing an anti-inflammatory effect. Usage of
: 2 times a day for the affected area, those with severe symptoms may need to use it continuously for more than 4 weeks to see obvious effect. It has basically the same effect as topical hormones, but the side effects are rarer and can be used for a longer time.
side effects: There may be discomfort such as itching, burning, and irritation in the initial stage of use. Long-term use may increase the risk of skin malignancies and lymphoma , but this side effect has not been fully proven, especially for the treatment of seborrheic dermatitis, which may not be sufficient to cause serious consequences when used on a small area.
commonly used such as 2% ketoconazole ointment , or miconazole, Be careful not to buy with compound ingredients, compound ingredients generally contain strong hormones and are not suitable for use on the face.
Mechanism of action: Antifungal.
usage: 2 times a day,Apply to the affected area. The effect may be weaker than topical corticosteroids and calcineurin immunosuppression. Suitable for mild facial seborrheic dermatitis.
Side effects: Contact dermatitis.
Other drugs that may be effective include topical metronidazole gel , topical benzoyl peroxide, topical non-steroidal anti-inflammatory drugs, etc., but the effects are not as precise as those described above.
In addition, Long-term seborrheic dermatitis may promote local vascular hyperplasia, forming persistent erythema or red blood , especially near the nasolabial fold. Such erythema drugs cannot achieve the effect of complete removal, and further treatment needs to be combined with photoelectric therapy for blood vessels.
3. Seborrheic dermatitis on body parts
The chest, back, armpits and groin are also prone to seborrheic dermatitis. Treated differently, the armpits and groin belong to the skin folds, and the medication is exactly the same as the face.
The skin on the chest and back is thicker. The only difference from facial treatment is that some more potent hormones can be used, which will take effect faster, such as topical mometasone furoate or compound flumetasone , etc. Pay attention to the use of hormones Time should not be too long .
Fourth, severe refractory seborrheic dermatitis
Severe refractory seborrheic dermatitis
The seborrheic dermatitis that cannot be controlled by topical medication, or combined with HIV-positive immunocompromised patients can try oral medication for seborrheic dermatitis. Commonly used antifungal itraconazole, terbinafine; and oil control and anti-keratinization isotretinoin.
The usage is oral 200mg per day,Taking for 1-2 weeks in a row may have better effect; some patients can appropriately extend the course of treatment or discontinue medication according to the situation to maintain the improvement. Itraconazole needs to be taken with meals, and there is a certain risk of causing abnormal liver function , and liver function needs to be monitored when taking it.
2, Oral Terbinafine Hydrochloride Tablets
The usage is 250 mg orally per day for 4-6 weeks. Or use the method of intermittent medication, taking 12 days a month for 3 consecutive months. Also pay attention to monitoring liver function .
The usage of is 10-20mg per day at the beginning, and the amount of is reduced as appropriate after symptoms improve. Because of the risk of side effects, it is less used to treat seborrheic dermatitis alone, and it is mostly used in combination with acne or rosacea .
There is no cure for seborrheic dermatitis, a once-and-for-all treatment method often requires maintenance therapy to reduce recurrence, or timely medication if there is recurrence. Drinking, dryness, stress, etc. are common predisposing factors, cultivate a healthy lifestyle, and usually pay attention to skin moisturizing, which can reduce recurrence.
In addition, the above-mentioned drugs are recommended based on the actual domestic situation of existing drugs, many of which are prescription drugs, which need to be combined with personal practical application under the guidance of doctors.
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The data of this article was updated on June 01, 2021 skin problems,Please consult your doctor in time.
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side effects: long-term use can cause skin atrophy , telangiectasia, folliculitis, hirsutism and hypopigmentation.
, topical calcineurin immunosuppression
commonly used is pimecrolimus cream or tacrolimus ointment .
Mechanism of action: Inhibits the production of cytokines by T lymphocytes , thereby playing an anti-inflammatory effect. Usage of
: 2 times a day for the affected area, those with severe symptoms may need to use it continuously for more than 4 weeks to see obvious effect. It has basically the same effect as topical hormones, but the side effects are rarer and can be used for a longer time.
side effects: There may be discomfort such as itching, burning, and irritation in the initial stage of use. Long-term use may increase the risk of skin malignancies and lymphoma , but this side effect has not been fully proven, especially for the treatment of seborrheic dermatitis, which may not be sufficient to cause serious consequences when used on a small area.
, topical antifungal ointment
commonly used such as 2% ketoconazole ointment , or miconazole, Be careful not to buy with compound ingredients, compound ingredients generally contain strong hormones and are not suitable for use on the face.
Mechanism of action: Antifungal.
usage: 2 times a day for the affected area. The effect may be weaker than topical corticosteroids and calcineurin immunosuppression. Suitable for mild facial seborrheic dermatitis.
Side effects: Contact dermatitis.
Other drugs that may be effective include topical metronidazole gel , topical benzoyl peroxide, topical non-steroidal anti-inflammatory drugs, etc., but the effects are not as precise as those described above.
In addition, Long-term seborrheic dermatitis may promote local vascular hyperplasia, forming persistent erythema or red blood , especially near the nasolabial fold. Such erythema drugs cannot achieve the effect of complete removal, and further treatment needs to be combined with photoelectric therapy for blood vessels.
3. Seborrheic dermatitis on body parts
The chest, back, armpits and groin are also prone to seborrheic dermatitis. Treated differently, the armpits and groin belong to the skin folds, and the medication is exactly the same as the face.
The skin on the chest and back is thicker. The only difference from facial treatment is that some more potent hormones can be used, which will take effect faster, such as topical mometasone furoate or compound flumetasone , etc. Pay attention to the use of hormones Time should not be too long .
Fourth, severe refractory seborrheic dermatitis
Severe refractory seborrheic dermatitis The seborrheic dermatitis that cannot be controlled by topical medication, or combined with HIV-positive immunocompromised patients can try oral medication for seborrheic dermatitis. Commonly used antifungal itraconazole, terbinafine; and oil control and anti-keratinization isotretinoin. 、Oral Itraconazole capsules
The usage is 200 mg orally every day, and continuous taking for 1-2 weeks may have better effects; some patients may appropriately extend the course of treatment or intermittently take medication according to the situation to maintain improvement. Itraconazole needs to be taken with meals, and there is a certain risk of causing abnormal liver function , and liver function needs to be monitored when taking it.
2, Oral Terbinafine Hydrochloride Tablets
The usage is 250 mg orally per day for 4-6 weeks. Or use the method of intermittent medication, taking 12 days a month for 3 consecutive months.Also pay attention to monitoring liver function .
, Oral isotretinoin
The usage of is 10-20mg per day at the beginning, and the amount of is reduced as appropriate after symptoms improve. Because of the risk of side effects, it is less used to treat seborrheic dermatitis alone, and it is mostly used in combination with acne or rosacea .
There is no cure for seborrheic dermatitis, a once-and-for-all treatment method often requires maintenance therapy to reduce recurrence, or timely medication if there is recurrence. Drinking, dryness, stress, etc. are common predisposing factors, cultivate a healthy lifestyle, and usually pay attention to skin moisturizing, which can reduce recurrence.
In addition, the above-mentioned drugs are recommended based on the actual domestic situation of existing drugs, many of which are prescription drugs, which need to be combined with personal practical application under the guidance of doctors.
[Disclaimer]
The data of this article was updated on June 01, 2021 For skin problems, please consult a doctor in time
