iPSCs were successfully induced to generate DA neurons. Recently, SQZ Biotechnology Company published medical data on reprogramming induced stem cells. Data show that the addition of non-viral, self-amplifying RNA enhances and prolongs the expression of transcription factors and

2024/04/1601:51:33 science 1779

iPSCs were successfully induced to generate DA neurons

Recently, SQZ Biotechnology Company published medical data on reprogramming induced stem cells. Data show that addition of non-viral, self-amplifying RNA enhances and prolongs expression of the transcription factor and supports the development of DA neurons . The company's proprietary cell Squeeze® technology enables the efficient generation of dopaminergic (DA) neurons from human induced pluripotent stem cells (iPSCs) through a single-step delivery of six RNAs encoding specific fate-determining transcriptional factors.

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