Patients with hypertension are prone to three major complications: complications of the heart, cerebrovascular and kidneys. Many patients with late hypertension experience severe renal impairment and ultimately require hemodialysis treatment. Once renal function damage occurs, it

Patients with hypertension are prone to three major complications: complications of the heart, cerebrovascular and kidneys. Many patients with late hypertension experience severe renal impairment and ultimately require hemodialysis treatment. Once renal function damage occurs, it is difficult to reverse it. Therefore, early detection and prevention can delay the further deterioration of renal function and protect renal function.

So, how can we detect renal function damage caused by hypertension in the early stage? It can be detected early from clinical manifestations and laboratory examinations.

There are few discomforts in clinical practice for early renal function problems. If the foam in the urine increases and does not fade for a long time, it may indicate an increase in protein in the urine, and sometimes it is accompanied by a darker color of the urine, which requires further examination.

Of course, in patients with severe renal insufficiency, symptoms of general fatigue and itching are mainly caused. Due to renal insufficiency, symptoms such as anemia, renal bone disease, hyperphosphatemia and other symptoms appear in the later stage;

Laboratory examination is the most reliable indicator:

First, check the routine urine test. Regular urine tests found proteinuria or red blood cells, but the probability of red blood cells is relatively low.

The second is to check for urine microalbumin. Urine microalbumin is a very sensitive indicator. When the amount of albumin in the urine is small and not enough to make urine protein positive in routine urine, it is possible to detect that microalbumin is quantitatively positive. The microalbumin in normal people is in the normal range. When renal impairment occurs, the first thing to detect is the quantification of microalbumin. As kidney damage worsens, urine protein gradually increases.

Therefore, urinary albumin is of great help in judging the severity of kidney disease, the efficacy, and the prognosis. Microalbumin is an indicator of early renal impairment. When blood pressure is not controlled well, urine microalbumin will increase, and as blood pressure decreases, this indicator may return to negative results.

The third is the change of kidney function. Generally, renal damage is less common in early renal function changes. If the examination shows that urea nitrogen and serum creatinine levels are increased, it means that hypertensive kidney damage is no longer early.

4 is the urine albumin/creatinine ratio. Detection of the ratio of urine albumin to urinary creatinine can determine whether there is microalbuminuria, that is, whether there is abnormal urinary albumin excretion. If the index is increased, it means that the albumin excretion in the urine of hypertensive patients is increased, which is mostly related to kidney changes in the early stage of hypertension. At this time, the excretion of urinary albumin increases, indicating that kidney lesions, especially endothelial cells are damaged.

is urine β2-microglobulin. Patients with hypertension can often check this indicator. If this indicator continues to increase significantly, it is a more sensitive indicator for early renal function damage.

For patients with hypertension, the above laboratory indicators are frequently checked and dynamic observations are of great significance for early detection of renal impairment. It can also guide you in the intensity of medication and the choice of medication. For people with early renal impairment, antihypertensive treatment is needed to strengthen antihypertensive treatment and control blood pressure below 130/80mmHg. It is best to choose Priligy or Sartan antihypertensive drugs with evidence-based medical evidence of renal protection.