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Cough is an advanced symptom of many respiratory diseases and is also a follow-up disturbance of many diseases. In particular, has a stubborn dry cough at night. In mild cases, it disturbs people's dreams, and in severe cases, it even causes complications such as chest pain, , lung vesicular, pneumothorax . How to deal with night cough and dry cough? Let’s learn about this issue together.
▌1. Why is the stubborn dry cough worsening at night?
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Nighttime Due to the increased excitability of the vagus nerve, under the action of acetylcholine , the respiratory smooth muscle tone increases and the tube diameter becomes smaller, which speeds up the airflow through the speed, and impacts the exposed nerve endings and the receptor organs in epithelial cells with increased sensitivity after inflammation, and has severe dry cough, which is high at night.
▌2. Selection of medication for stubborn dry cough at night?
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For stubborn dry cough at night, anti-infection treatment is often given clinically, which is expensive and has little effect. It has to be given central antitussive medicine , but is very easy to addictive .
Compound bromopropylamine Tailin Tablets The core of the tablet is made of bromopropylamine Tailin, chlorphenamine maleate , Ganoderma lucidum powder and auxiliary materials, and the auxiliary materials are composed of starch and magnesium stearate. This drug belongs to antitussive expectorant , and its effects are:
1, competitively blocking the excitatory effect of acetylcholine on the M receptor, relieving respiratory cramps and inhibiting gland secretion.
2, H1 receptor blocking effect can combat allergic symptoms caused by histamine , relieve respiratory cramps and inhibit gland secretion, and also have a mild sedation effect.
3. Adding Chinese medicine Ganoderma lucidum powder has a certain immune regulation effect.
Compound bromopropylamine Tailin Tablets are suitable for the treatment of night cough, dry cough, and irritating cough.
▲ For medical professional reading reference only, use
Clinical study of the use of bromopropylamine Tailin tablets in the selection literature in this issue for the treatment of nighttime refractory dry cough , for medical reference only.
▌3. Treatment of 283 cases of stubborn dry cough at night with stubbornness in the treatment of 283 cases of
☉ Case data :
The 8th Hospital of the People's Liberation Army used bromopropylamine to treat nightly stubborn dry cough 283 patients, acute upper respiratory tract infection still had dry cough (21.56%); acute bronchitis nightly stubborn cough 169 cases (59.72%). Among them, 114 cases of asthma were combined with at night, ; 313 cases of asthma were still dry cough at night (4.59%); 18 cases of chronic bronchitis (6.36%); 22 cases of unknown cause (7.77%).
☉ Treatment methods :
In addition to the short-term (less than one week) antibiotics, all of them were given oral premature pyramidine bromide tablets alone, 15mg to 30mg for adults, 0.5mg per kilogram of weight per kilogram of children, and the maximum amount generally does not exceed 30mg. It is taken orally once before going to bed for 3 days, generally does not exceed 5 days. Otherwise, choose another method or use it in combination.
☉ Treatment data :
☉ Treatment results : 232 cases (81.98%) were taken
for three consecutive times to stop the medication and relieve cough. Among them, 114 cases with combined with nocturnal asthma, all of which were relieved asthma and relieve cough. 40 cases (14.13%) were taken 5 times to stop the medication and relieve cough. Only 11 cases (3.89%) were used in combination or alternative methods.
☉ Treatment conclusion:
From the treatment situation of 283 cases, the efficacy is 96.11%. Propylamine bromide Tailin is particularly suitable for the treatment of patients with cough and nighttime asthma ; it is convenient to use, has a wide source of medicine, is low-priced, and has no addiction. and has no addiction. Except for some cases where there are mild dry mouth , no other toxic side effects are seen, and it is particularly suitable for the promotion and use of primary medical units .
This paper explains the mechanism of action of compound bromopropylamine Tailin Tablets in the treatment of nighttime stubborn dry cough and typical clinical studies. In addition to treating night dry cough , this product can also treat dry cough and irritating cough caused by other reasons. The introduction will continue in the future, so stay tuned.
References:
[1] Shen Weiyi, Fan Xuehui, Wu Hongliang, et al. 283 cases of night-stubborn dry cough treated with tailin from propylamine bromide [J]. Southwest National Defense Medicine, 2002, 12(2):173-174.