As the living standards improve. The lifespan of ordinary people has been greatly extended, and our country has now entered an aging society. Osteoporosis is one of the most common and frequent geriatric diseases. Osteoporosis poses a great threat to the quality of life and life of elderly patients. Due to osteoporosis, , microfracture, bone and joint degeneration, and even fractures, the patient has long-term chronic pain or joint movement disorders. It has a great impact on the mental health status of elderly patients.
Mechanism
There are some common neurobiological pathways and common chemical regulatory substances between pain and depression.
1) Due to the loss of life ability and the decline in quality of life caused by pain, fractures and complications, the risk of depression in osteoporosis patients is significantly increased;
2) Depression can also further aggravate the abnormal feelings of the patients. Depression is also a risk factor for osteoporosis, and the three can form a vicious cycle.
Patients with osteoporosis have a decline in their quality of life due to long-term chronic pain and activity disorders, which induces or aggravates the occurrence of anxiety and depression. As the anxiety and depression worsen, the quality of life decreases accordingly, which eventually leads to the decline of the patient's physical and motor function and the decline of daily life activities, indicating that mental depression may accelerate the process of osteoporosis. Depressed emotions can stimulate the sympathetic nerve system to release norepinephrine, which damages the cells that make bones. This study also shows that antidepressants can block norepinephrine and reverse its negative effects.
treatment
psychological intervention may regulate autonomic nerve , endocrine system and immune system through various functions of the brain, affecting the metabolism of the body's calcium and phosphorus metabolism system and inflammatory factors, thereby affecting the reduction of pain in patients with osteoporosis.
The quality of life of patients with osteoporosis is related to anxiety and depression. When diagnosing and treating patients with osteoporosis, if you can pay attention to the anxiety and depression emotional problems of patients on the basis of standardized anti-osteoporosis drug treatment, it will not only help psychological diseases, but also play a positive role in organic lesions.
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