Currently, the new crown special medicine on the market, and mainly includes the oral special medicine of Merck, the oral special medicine of Pfizer, and the oral special medicine of Shinoyi, Japan. Among them, Pfizer oral special drugs have obtained the import license of in my country, and are represented by China Medical .
According to relevant news, Pfizer's oral special medicine for the new crown is 2,300 yuan per box of
According to relevant news, Pfizer's oral special medicine is 2,300 yuan per box, and one box can be taken for 5 days. Although it has been included in the medical insurance, I believe that this fee is relatively expensive for most people. , so everyone put their hopes on the domestic COVID-19 special medicine . At present, the main things that are progressing faster in my country are Junshi Bio VV116 and real creature Azvding .
Recently, there has been a lot of news about Azvding. On March 10, Zhenbi applied for a Class II communication meeting to the Drug Review Center of the State Drug Administration, and on April 2, he applied for a Class III communication meeting. At the China Medical Development Conference held in Beijing on April 16, Academician of the Chinese Academy of Engineering Jiang Jiandong reported the latest R&D status and progress of Azfuding. According to relevant information, Azfuding is getting closer to its listing.
1. Understand Azvdine
We opened a certain encyclopedia and saw the introduction of Azvdine. Azvdine is an HIV reverse transcriptase inhibitor that can effectively inhibit the reverse transcription and replication of HIV in the body. You will definitely be a little confused. Are you mistaken? Are Azfuding, who treats AIDS and Azfuding, who treats , the same thing as Azfuding, who treats the new coronavirus?
Azfuding's encyclopedia introduction
This is actually a thing. As early as 2013, real creatures began researching Azfuding. At that time, it was , a drug used for AIDS, which had a relatively good therapeutic effect on anti-Azfuding treatment, and was approved for marketing in my country in July 2021.
The outbreak of the new coronavirus in 2020, real creatures discovered that Azvdine can also be used for the treatment of the new coronavirus. In clinical trials, Azvdine can quickly turn negative. And judging from the current research progress, Azvdin's stage is not only in the field of AIDS, but also in the treatment of the new coronavirus and hand, foot and mouth virus .
2, Principle of Azfuding
Academician Jiang also introduced the pharmacological mechanism of Azfuding for the treatment of the new coronavirus. Compared with other drugs, Azfuding only triphosphorylated in thymus , clearing the virus in the thymus, protecting the immune system, thus producing an antiviral effect, which not only treats the symptoms (antiviral) but also treats the root cause (thymus protection).
3. The effect of Azfuding
According to Academician Jiang’s speech, the clinical effect of Azfuding is like this: generally taking oral medicine for 3-4 days to turn negative nucleic acid. There were about 300 to 400 cases in the second phase clinical trial, and more than 800 cases in the third phase clinical trial. From the results of the second phase clinical and part of the third phase clinical clinical results, nucleic acid turns negative in about 3-4 days. You can stop taking the medicine for 6-7 days and usually discharged from the hospital in 9 days. At the cellular level, although the antiviral strength of is slightly worse than that of remdesivir , it is significantly better than that of remdesivir in terms of clinical effects.
4, Azfuding related supply chain
Azfuding was developed by Henan Real Bio, but because Real Bio is not listed, in A-share market , it is more about Azfuding's raw materials and intermediate supply chain companies.
Tuxin Pharmaceutical : Like real creatures, it is also located in Henan, and has strong strength in the development and production of domestic nucleoside (acid) pharmaceutical intermediate products. Subsidiary Xinxiang Pharmaceutical is a manufacturer of Azfuding raw materials. can be said that Tuoxin Pharmaceutical is a company deeply bound to Real Bio, and it is relatively certain as a supplier of Azfuding raw materials.The stock's trend is also very strong. From 25 yuan to 25 yuan, it almost didn't adjust much, and it rose to 230 yuan. A few days ago, under the influence of the sharp drop in the special drug sector and the sharp drop in market , it finally ushered in an adjustment. The rise has increased again in the past three days, and it is about to recover the lost land and launch another attack on the high point of 230.
Aoxiang Pharmaceutical : The company is located in Zhejiang, mainly engaged in the research and development, production and sales of pharmaceutical preparations, specialty raw materials, and key pharmaceutical intermediates, as well as providing customers with customized processing and R&D business. As one of the company's top 5 customers, Peking Union Medical College Pharmaceutical Factory is a manufacturer of Azfuding, so Aoxiang Pharmaceutical is also very likely to enter Azfuding's supply chain. At the same time, Aoxiang Pharmaceutical may also be the raw material supplier of Kaituo Pharmaceutical, so during this period, Aoxiang Pharmaceutical's trend has been very strong.
China Resources Double He : The company's main business covers new drug research and development, preparation production, drug sales, pharmaceutical equipment and raw material production. In the secondary market, the company has risen sharply recently and its stock price has also changed significantly. The reason is a rumor in the market. According to the rumor, China Resources Shuanghe will sign an Azfuding agency production and sales agreement with Real Bio. Although China Resources Double Crane releases an announcement denies the rumor. You should know that at the beginning, the market was also rumored that China Pharmaceutical would be a proxy for Pfizer special medicine. China Pharmaceutical also denied it. After a few days, it issued an official agency announcement. , so in the capital market, it is often not groundless. If the agency agreement is really signed later, what will happen? You can take a look at the trend after China Pharmaceutical signs the agreement.
Because of the huge market demand for special drugs, if domestically produced new crown drugs are successfully developed and launched, it will not only bring hope to end the epidemic, but also related supply chain listed companies will also perform in the capital market. On December 25, 2021, Kaituo Pharmaceutical, listed in Hong Kong, failed to unblindly in the progress of the new coronavirus specific drugs, and its stock price fell from a high of 45 yuan to a low of 6.9 yuan in one day. On April 6, 2022, Kaituo Pharmaceutical disclosed its latest progress, which had good clinical results in the third phase, and then the stock price rose by 200% in one day.
So if Azfu can definitely win the lead in the market for the domestically produced new crown special-effect oral medicine, it will definitely have a good increase. If the progress is less than expected, it will be the same as Kaituo Pharmaceutical on December 25. No matter what, I still hope that Azvding can be successfully developed and launched as soon as possible. The current epidemic has not only affected the economy, but also brought great inconvenience to people's lives. I also really hope that Azvdin can become the endorseor of the new coronavirus epidemic.
